The role of exogenous growth-promoting factors and their receptors in organogenesis

International Journal of Developmental Biology

Volumn 41, Issue 2, 1997, Pages 319-328

  Pratten, Margaret K ^a  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

Author keywords

embryo culture; growth factors; microcannulation; yolk sac

Indexed keywords

EPIDERMAL GROWTH FACTOR; GROWTH FACTOR RECEPTOR; INSULIN; SOMATOMEDIN C;

ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; GROWTH REGULATION; HORMONE RECEPTOR INTERACTION; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; RAT; YOLK SAC;

ANIMALS; CULTURE TECHNIQUES; EMBRYONIC AND FETAL DEVELOPMENT; EPIDERMAL GROWTH FACTOR; FEMALE; GROWTH SUBSTANCES; INSULIN; PREGNANCY; RECEPTORS, GROWTH FACTOR; YOLK SAC;

EID: 0030910227     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (108)

1. ABBOTT, B.D. and PRATT, R.M. (1991). Retinoic acid alters epithelial differentiation during palatogenesis. J. Craniofac. Genet. Dev. Biol 11: 315-325
2. ABELEV, G I. (1971). Alphafetoprotein in ontogenesis and its association with malignant tumors Adv Cancer Res. 14: 295-358.
3. ADAMSON, E.D. (1983). Growth factors in development. In The Biological Basis of Reproductive and Developmental Medicine (Ed. J B. Warshaw). Edward Arnold, London, pp 307-336
4. ADAMSON, E D. (1990). EGF receptor activities in mammalian development. Mol Reprod. Dev 27: 16-22.
5. ADAMSON, E D (1993a). Two proto-oncogenes that play dual roles in embryonal cell growth and differentiation. Int. J. Dev Biol. 37: 111-116.
6. ADAMSON, E.D. (1993b) Growth-factors and their receptors in development. Dev. Genet. 14: 159-164.
7. ADAMSON, E D and MEEK, J. (1984). The ontogeny of EGF receptors during mouse development. Dev. Biol 103: 62-70.
8. ADAMSON, E.D., DELLER, M.J. and WARSHAW, J B. (1981). Functional EGF receptors are present on mouse embryo tissues. Nature 291: 656-659.
9. ANDREWS, K.E., PRATTEN, M.K. and BECK, F. (1987) Epidermal growth factor: pinocytosis and effect on embryonic development Biochem Soc Trans. 15: 920-921
10. ANWAR, M and BECK, F (1988). The evaluation of human serum as a culture medium in rat embryo culture studies. Reprod. Toxicol. 2: 135-140.
11. ANWAR, M., MACVICAR, J and BECK, F. (1987). Evaluation of the teratogenicity of serum from patients with histories of recurrent miscarriages using an in-vitro whole embryo culture technique. Br J Obstet. Gynaecol. 94: 918
12. ANWAR, M., MACVICAR, J. and BECK, F. (1989). Serum from pregnant women carrying a fetus with a neural tube defect is teratogenic for rat embryos. Br. J. Obstet. Gynaecol 96: 33-37.
13. ANWAR, M., MACVICAR, J and BECK, F (1990). Teratogenicity of valproic acid in rats and humans Contemp. Rev. Obstet. Gynaecol. 2: 5-10.
14. BAKER, J., LIU, J P , ROBERTSON, E.J and EFSTRADIADIS, A. (1993). Role of insulin-like growth factors in embryonic and post-natal growth. Cell 75 73-82.
15. BASEGRA, R. and RUBIN, R. (1993) Cell cycle and growth control Crit. Rev. Gene Expression 3: 47-61.
16. BECK, F , MENSAH-BROWN, E. and PRATTEN, M.K. (1987a). Development of a method for assessing the acute toxicity of chemicals on early post-implantation embryos. Arch. Toxicol. 11 (Suppl.). 155-158.
17. BECK, F., SAMANI, N.J , PENSHOW, J.D., THORLEY, B., TREGEAR, G.W. and COGHLAN, J P. (1987b). Histochemical localization of IGF-I and -II mRNA in the developing rat embryo. Development 101: 175-184
18. BROWN, N. A. and FABRO, S (1981). Quantitation of rat embryonic development in vitro: A morphological scoring system. Teratology 224. 65-78.
19. BROWN, N A. and FABRO, S.E (1982). The in vitro approach to teratogenicity testing. In Developmental Toxicology (Ed. K. Snell). Croom Helm, London, pp. 33-57
20. BROWN, N.A., GOULDING, E.H. and FABRO, S. (1979). Ethanol embryotoxicity: direct effects on mammalian embryos in vitro. Science 206: 573-575.
21. BRUNET, C L, SHARPE, P.M and FERGUSON, M.W J. (1993). The distribution of epidermal growth factor binding sites in the developing mouse palate. Int. J. Dev. Biol. 37: 451-458.
22. CHATOT, C L, KLEIN, N.W., PIATEK, J. and PIERRO, L.J (1980). Successful culture of rat embryos in human serum, use in detection of teratogens Science 207. 1471-1473.
23. CICUREL, L and SCHMID, B P. (1988). Postimplantation embryo culture for the assessment of the teratogenic potential and potency of compounds Experientia 44: 833-840.
24. CLODE, A M., PRATTEN, M.K. and BECK, F. (1987). A stage- dependant effect of ethanol on 9.5 day rat embryos grown in culture and the role played by the concomitant rise in osmolality. Teratology 35: 395-403.
25. COCKROFT, D.L. (1984) Abnormalities induced in cultured rat embryos by hyperglycaemia. Br J Exp. Pathol. 65:625-636.
26. COCKROFT, D L. (1988) Changes with gestational age in the nutritional requirements of postimplantation rat embryos in culture. Teratology 38: 281-290
27. COHEN, S. (1962) Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. J Biol Chem 237: 1555-1562.
28. COWLEY, E.A. and PRATTEN, M.K. (1992) Analysis of the receptor complement for insulin and insulin-like growth factor I (IGF-I). in the rat visceral yolk sac placenta Biochem Soc. Trans. 20: 280.
29. COWLEY, E.A. and PRATTEN, M.K. (1996). Processing of fluorescently labelled insulin and insulin-like growth factor-I by the rat visceral yolk sac Placenta 17: 321-327.
30. CUMBERLAND, P F.T and PRATTEN, M.K (1993) Differences in binding characteristics of rat and human transferrin by rat visceral yolk sac placenta Placenta 14: 287-307.
31. CUMBERLAND, P.F T and PRATTEN, M.K (1995) Teratogenicity of thalidomide-related compounds in vitro. Teratology 51: 22A.
32. CUMBERLAND, P.F.T., RICHOLD, M , PARSONS, J. and PRATTEN, M.K (1992a). Intravitelline injection of cultured rat embryos: an improved method for the identification of cytotoxic and non-cytotoxic teratogens Toxicol. In Vitro 6: 503-508.
33. CUMBERLAND, P.F.T., RICHOLD, M., PARSONS, J. and PRATTEN, M.K (1992b) Intravitelline injection of rodent conceptuses an improved in vitro developmental toxicity screen. Toxicol. In Vitro 8: 731-733
34. CUMBERLAND, P F.T , RICHOLD, M , PARSONS, J and PRATTEN, M.K. (1994). Further evaluation of a teratogenicity screen using an intravitelline injection technique Toxicol. In Vitro 8. 153-166
35. DEALY, C N. and KOSHER, R A. (1996). IGF-I, insulin and FGFs induce outgrowth of the limb buds of amelic mutant chick embryos. Development 122: 1323-1330.
36. DICKSON, M.C., MARTIN, J S , COUSINS, F M., KULKARNI, A.B., KARLSSON, S. and AKHURST, R.J. (1995) Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice. Development 121 1845-1854.
37. DUNCAN, R. and LLOYD, J B (1978). Pinocytosis in the rat visceral yolk sac: effect of temperature, metabolic inhibitors and some other modifiers. Biochim Biophys Acta 544: 647-655
38. DUNCAN, R. and PRATTEN, M.K. (1985). Pinocytosis: mechanism and regulation In Mononuclear Phagocytes, Physiology and Pathology (Eds. R T. Dean and W. Jessup). Elsevier Scientific Publishers BV, London, pp. 27-51.
39. DUNTON, A., AL-ALOUSI, L.A., PRATTEN, M.K. and BECK, F. (1986). The giant yolk sac: a model for studying early placental transport. J. Anat. 145: 189-206.
40. 125I-labelled bovine serum albumin by the rat visceral yolk sac cultured in vitro as a closed vesicle. Placenta 9: 303-311.
41. FERGUSON, M.W.J., SHARPE, P.M., THOMAS, B.L. and BECK, F. (1992). Differential expression of insulin-like growth factors i and ii (IGF I and II), mRNA, peptide and binding protein 1 during mouse palate development: comparison with TGF beta peptide distribution. J. Anat. 181: 219-238.
42. FLORANCE, R.S.K., SENIOR, P.V., BYRNE, S. and BECK, F. (1991). The expression of IGF-II in the early post-implantation rat conceptus. J. Anat. 175: 169-179.
43. FRANCIS WEST, P and TICKLE, C. (1996). Limb development Curr. Top. Microbiol Immunol. 212: 239-259
44. FREEMAN, S J , BECK, F. and LLOYD, J.B. (1981). The role of the visceral yolk sac in mediating protein utilisation by rat embryos cultured in vitro. J Embryol Exp. Morphol 66: 223-234.
45. GAZIT, A., YAISH, P., GILON, C. and LEVITZKI, A. (1989). Tyrphostins 1. Synthesis and biological activity of protein tyrosine kinase inhibitors. J. Med. Chem. 32: 2344-2352.
46. GLUCKMAN, P.D. (1986). Role of pituitary hormones, growth factors and insulin in regulation of fetal growth. Oxford Rev. Reprod. Biol. 8: 1-60.
47. GULAMHUSEIN, A P , PRATTEN, M.K., WILLIAMS, C A. and BECK, F. (1990). The effect of macromolecular rat serum fractions on conceptuses cultured in human serum, role of transferrin. J. Anat. 168: 113-121.
48. HAN, V.K.M., D'ERCOLE, A.J. and LUND, P K. (1987) Cellular localisation of somatomedia (insulin-like growth factor) messenger RNA in the human fetus. Science 236: 193-197
49. HILL, W.C , PELLE-DAY, G., KITZMILLE, J.L. and SPENCER, E.M. (1989) Insulin-like growth factors in fetal macrosomia with and without maternal diabetes Hormone Res. 32: 178-182.
50. HORTSCH, M , SCHLESSINGER, J , GOOTWINE, E. and WEBB, C.G. (1983). Appearance of functional EGF receptor kinase during rodent embryogenesis. EMBO J. 2: 1937-1941
51. HUANG, L , SOLURSH, M. and SANDRA, A. (1996). The role of transforming growth factor alpha in craniofacial development and chondrogenesis. J Anat. 189: 73-86.
52. HUET-HUDSON, Y.M., ANDREW, G.K and DEY, S K. (1990). Epidermal growth factor and pregnancy in the mouse. In Early Embryo Development and Paracnne Relationship (Eds S. Hener and L M. Wiley) Wiley -Liss, New York, pp. 125-136
53. HUXHAM, I M and BECK, F. (1981). Receptor mediated coated vesicle transport of rat IgG across the 11.5 day in vitro rat yolk sac Cell Biol Int. Rep 5: 1073-1081.
54. HUXHAM, I.M. and BECK, F (1984). Characterisation of exocoelomic fluid protein from rat conceptuses cultured in rat and human sera: a measure of yolk sac activity during organogenesis. J. Embryol. Exp. Morphol 84: 203-215.
55. HUXHAM, I.M and BECK, F. (1985). Maternal transfernn uptake by and across the visceral yolk sac of the early postimplantation rat conceptus in vitro Dev. Biol. 110: 75-83.
56. KITCHEN, K T., SCHMID, B P and SANYAL, M K (1986). Rodent whole-embryo culture as a teratogen screening method. Methods Finds Exp. Clin Pharmacol. 8: 291-301
57. KLEIN, N.W., CAREY, S.W , CHATOT, C.L., FISH, H.W , GAMETT, D.C., HAINES, J S , PIERRO, L.J., PLENEFISCH, J.D. and YOUNG, M.F (1983). The use of cultured rat embryos to detect teratogens in serum from rats, humans and monkeys In In Vitro Testing of Environmental Agents (Eds. A.R. Kolber, T.K Wong, L.D Grant, R.S. Dewoskin and T.J. Hughes). Plenum Press, New York-London, pp 209-230
58. KLEIN, N.W., MINGHETTI, P.P., JACKSON, S.K. and VOGLER, M A. (1978). Serum depletion by cultured rat embryos. J. Exp. Zool. 203: 313-318.
59. KLUG, S , LEWANDOWSKI, C., WILDI, L. and NEUBERT, D (1989). All-trans retinoic acid and 13-cis-retinoic acid in the rat whole-embryo culture abnormal development due to the all-trans isomer. Arch. Toxicol. 63 440-444.
60. LASSARE, C., HARDOUIN, S., DAFFOS, F., FORESTIER, F., FRANKENNE, F. and BINOUX, M (1991). Serum insulin-like growth factors and insulin-like growth factor binding proteins in the human fetus: relationship with growth in normal subjects and in subjects with intra-uterine growth retardation. Pediatr. Res. 29: 219-225
61. LEVITZKI, A (1992). Tyrphostins tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction. FASEB J. 6: 3275-3282
62. LEVITZKI, A and GILON. C. (1991). Tyrphostins as molecular tools and potential antiprohferative drugs. Trends. Pharm. Sci. 12: 171-174
63. LIU, J P., BAKER, J., PERKINS, A S., ROBERTSON. E.J. and EFSTRATIADIS, A. (1993). Mice carrying null mutations of the genes encoding insulin-like growth factor I (IGF-I) and type 1 IGF receptor (IGF1r). Cell 75: 59-72.
64. 125I-labeled protein by rat yolk sacs (Evidence for intracellular degradation within lysosomes). Biochem. J. 184: 519-526.
65. LUETTEKE, N.C., PHILLIPS, H.K., QIU, T.H., COPELAND, N.G., EARP, H.S., JENKINS, N.A. and LEE, D.C. (1994). The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase. Genes Dev. 8: 399-413.
66. LUETTEKE, N C., QUI, T.H., PEIFFER, R.L , OLIVER, P., SMITHIES, O. and LEE, D.C. (1993). TGFalpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice. Cell 73: 263-278
67. MACIAS, D., GANAN, Y., ROS, M.A. and HURLE, J.M. (1996). In vivo inhibition of programmed cell death by local administration of FGF-2 and FGF-4 in the interdigital areas of the embryonic chick leg bud. Anat. Embryol. 193: 533-541.
68. MANN, G.B., FOWLER, K J., GABRIEL, A., NICE, E C., WILLIAMS, R.L. and DUNN, A R. (1993). Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair and curly whiskers and often develop corneal inflammation. Cell 73: 249-261.
69. MCARDLE, H.J and PRISCOTT, P.K (1984). Uptake and metabolism of transferrin and albumin by rat yolk sac placenta. Am. J. Physiol 247: 1.
70. MCGARRITY, C., SAMANI, N., BECK, F. and GULAMHUSEIN, A.P. (1981). The effect of sodium salicylate on the rat embryo in culture: an in vitro model for the morphological assessment of teratogenicity. J. Anat. 133. 257-269.
71. 125I-labelled proteins after injection into 11.5 day rat embryonic circulation. Biochem. Soc Trans 15: 922-923.
72. MENSAH-BROWN, E.P.K., PRATTEN, M K. and BECK, F. (1989). A method for studying rat embryonic metabolism by cannulation of the vitelline circulation. J. Anat. 163: 123-134.
73. MERCOLA, M. and STILES, C.D. (1988). Growth factor superfamilies and mammalian embryogenesis. Development 102: 451-460
74. MILLER, P M., PRATTEN, M.K. and BECK, F. (1989) Growth of 9.5 day rat embryos in folic acid deficient serum. Teratology 39: 375-385.
75. NEW, D.A.T (1978). Whole embryo culture and the study of mammalian embryos during organogenesis. Biol Rev. 53:81-122.
76. NEXO, E., HOLLENBERG, M.D., FIGUEROA, A. and PRATT, R.M. (1980) Detection of epidermal growth factor-urogastrone and its receptor during fetal mouse development. Proc. Natl. Acad. Sci USA 77: 2782-2795.
77. PARIA, B C and DEY, S K. (1990) Pre-implantation embryo development in vitro: Cooperative interactions among embryos and role of growth factors. Proc. Natl. Acad. Sci USA 87: 4756-4760
78. PICARD, JJ and VAN MAELE FABRY, G. (1987). A new method to express embryotoxic data obtained in vitro on whole murine embryos. Teratology 35. 429-437.
79. POPLIKER, M , SHATZ, A., AVIVI, A., ULLRICH, A., SCHLESSINGER, J. and WEBB, C G. (1987) Onset of endogenous synthesis of epidermal growth factor in neonatal mice. Dev Biol. 119 38-44.
80. PRATTEN, M.K., BROOKE, A.M., BROOME, S.C and BECK, F. (1988). The effect of epidermal growth factor, insulin and transferrin on the growth promoting properties of serum depleted by repeated culture of postimplantation rat embryos Development 104: 137-145
81. PRATTEN, M.K., DUNTON, A. and BECK, F (1987) The "giant" yolk sac: a model for studying transport across extra-embryonic membranes. Arch. Toxicol. 11 (Suppl.): 159-162
82. RAABERG L., NEXO, E , DAMSGAARD-MIKKELSEN, J. and POULSEN, S.S. (1988). Immunohistochemical localisation and developmental aspects of epidermal growth factor in the rat Histochemistry 89. 351-356.
83. RIZZINO, A. (1987). Defining the roles of growth factors during early mammalian development. In The Mammalian Preimplantation Embryo. Regulation of Growth and Differentiation in Vitro (Ed B B Bavister). Plenum Press, New York-London, pp. 151-174.
84. 198Au] gold by rat yolk sac cultured in vitro. Biochem. J 168: 239-244
85. ROULIER, S., ROCHETTEEGLY, C., REBUTBONNETON, C , PORQUET, D. and EVAINBRION, D. (1994). Nuclear retinoic acid receptor characterization in cultured human trophoblast cells: effect of retinoic acid on epidermal growth factor receptor expression. Mol. Cell. Endocrinol. 105: 165-173
86. ROWLANDS, P.C., MIDDLETON, M.C and BECK, F. (1988). Cytochrome P450 catalysed activity in the rat visceral yolk sac. Hum. Toxicol. 7. 375-376,
87. SADLER, T.W. (1980). Effects of maternal diabetes on early embryogenesis 1. Teratogenic potential of diabetic serum Teratology 21: 339-347.
88. SANYAL, M K. (1980). Development of the rat in vitro and associated changes in components of the culture medium. J. Embryol Exp. Morphol. 58: 1-12.
89. SASSANI, R., BARTLETT, S.P , FENG, H , GOLDNER-SAUVE, A , HAQ, A.K., BUETOW, K H. and GASSER, D.C. (1993) Association between alleles of the transforming growth factor alpha locus and the occurrence of cleft lip. Am. J Med. Genet 45. 565-569.
90. SENIOR, P.V., BYRNE, S., BRAMMAR, W.J. and BECK, F. (1990) Expression of the IGF-II/mannose-6-phosphate receptor mRNA and protein in the developing rat. Development 109. 67-73
91. SHARPE, P.M., BRUNET, C.L and FERGUSON, M.W.J (1992). Modulation of the epidermal growth factor of mouse embryonic mesenchymal cells in vitro by growth factors. Int. J. Dev. Biol. 36: 275-282
92. SHASTRY, B.S (1994) More to learn from gene knockouts. Mol. Cell. Biochem 136: 171-182
93. SIBILIA, M. and WAGNER, F E. (1995) Strain dependent epithelial defects in mice lacking EGF receptor Science 269. 230-233.
94. SIMPSON, A.E C.M., BRAMMAR, W.J., PRATTEN. M.K. and ELCOMBE, C.R. (1995) Placental transfer of the hypolipidemic drug, clofibrate, induces CYP4A expression in 18.5 day fetal rats. Drug Metab. Dispos. (In press).
95. SMITH, E P., SADLER, T.W and D'ERCOLE, A.J (1987). Somatomedins/insulin-like growth factors, their receptors and binding proteins are present during mouse embryogenesis Development 101: 73-82.
96. STEELE, C E and COPPING, G.P (1990). Teratogen testing. In Postimplantation Mammalian Embryos (Eds. A J Copp and D L. Cockcroft). IRL Press, Oxford.
97. STEELE, C E , MARLOW, R., TURTON, J. and HICKS, R M. (1987). In vitroteratogenicity of retinoids. Br J. Exp. Pathol. 68: 215-223.
98. TEBBS, C A., CUMBERLAND, P.F T and PRATTEN, M.K. (1997). The effect of maternally derived epidermal growth factor during organogenesis of the rat embryo. J Anat. (In press).
99. THREADGILL, D.W., DLUSGOSZ, A.J., HANSEN, L.A., TENNENBAUM, T., LICHTI, U., YEE, D , LAMANTI, C., MOURTON, T., HERRUP, K., HARRIS, R.C., BARNARD, J.A , YUSPA, S H., COFFEY, R.J. and MAGNUSSEN, T. (1995). Targeted disruption of mouse EGF receptor effect of genetic background on mutant phenotype. Science 269. 230-233.
100. TRAVERS, J.P. (1989) Studies relating to Rat diabetic embryotoxicrty. PhD Thesis, University of Leicester.
101. TRAVERS, J.P , EXELL, L , HUANG, B., TOWN, E., LAMMIMAN, M J , PRATTEN, M K and BECK, F. (1992). Insulin and insulin-like growth factors in embryonic development, effects of a biologically inert insulin (guinea pig). upon rat embryonic growth and development in vitro. Diabetes 41: 318-324.
102. TRAVERS, J.P , PRATTEN, M K and BECK, F. (1989). The effects of low insulin levels upon rat embryonic growth and development. Diabetes 38:773-778
103. TWARDZIK, D R., RANCHALIS, J.E. and TODARO, G.J (1982). Mouse embryonic transforming growth factors related to those isolated from tumour cells. Cancer Res. 42: 590-593.
104. VAAHTOKARI, A., ABERG, T. and THESLEFF, I. (1996). Apoptosis in the developing tooth: Association with an embryonic signaling center and suppression by EGF and FGF-4. Development 122. 121-129.
105. 125I labelled immunoglobulin G within rat visceral yolk sacs incubated in vitro Biochem. J. 214 815-822
106. WILCOX, J.N and DERYNCK. R. (1988). Developmental expression of transforming growth factors alpha and beta in mouse fetus. Mol. Cell. Biol. 8. 3415-3422.
107. 125I)polyvinylpyrrolidone by rat yolk sac cultured in vitro J. Cell Biol 64 112-122
108. WILLIAMS, K.E., KIDSTON, E M., BECK, F. and LLOYD, J.B. (1975b). Quantitative studies of pinocytosis. II. Kinetics of protein uptake and digestion by rat yolk sac cultured in vitro. J. Cell Biol. 64: 123-134.