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Volumn 17, Issue 1, 1997, Pages 61-68

Frequency of the variant allele CYP2D6(C) among North American Caucasian lung cancer patients and controls

Author keywords

debrisoquine; genetic susceptibility; lung cancer

Indexed keywords

4 HYDROXYDEBRISOQUINE; DEBRISOQUINE; DRUG METABOLIZING ENZYME;

EID: 0030909631     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-5002(97)00649-1     Document Type: Article
Times cited : (6)

References (16)
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    • Broly F, Meyer UA. Debrisoquine oxidation polymorphism: phenotypic consequences of a 3-base-pair deletion in exon 5 of the CYP2D6 gene. Pharmacogenetics 1993; 3: 123-130.
    • (1993) Pharmacogenetics , vol.3 , pp. 123-130
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  • 3
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    • The determination of debrisoquine and its 4-hydroxy metabolite in urine by capillary gas chromatography and high performance liquid chromatography
    • Fox SD, Shaw GL, Caporaso NE, Welsh SE, Mellini DW, Falk RT, Issaq HJ. The determination of debrisoquine and its 4-hydroxy metabolite in urine by capillary gas chromatography and high performance liquid chromatography. J Liq Chromatogr 1993; 16: 1315-1327.
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  • 4
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    • Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism
    • Gaedigk A, Blum M, Gaedigk R, Eichelbaum M, Meyer UA. Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism. Am J Hum Genet 1991; 48: 943-950.
    • (1991) Am J Hum Genet , vol.48 , pp. 943-950
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  • 5
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    • Graf T, Broly F, Hoffman F, Probst M, Meyer UA, Howald H. Prediction of phenotype for acetylation and for debrisoquine hydroxylation by DNA-tests in healthy human volunteers. Eur J Clin Pharmacol 1992; 43: 399-403.
    • (1992) Eur J Clin Pharmacol , vol.43 , pp. 399-403
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    • Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification
    • Heim M, Meyer UA. Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification. Lancet 1990; 336: 529-532.
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    • Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine
    • Kagimoto M, Heim M, Kagimoto K, Zeugin T, Meyer UA. Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. J Biol Chem 1990; 265: 17209-17214.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.