Fluoromethylhistidine inhibits tumor growth without producing depletion of endogenous histamine

Inflammation Research

Volumn 46, Issue 1, 1997, Pages

  Cricco, G ^a   Engel, N ^a   Croci, M ^a   Davio, C ^a   Martin G ^a   Fitzsimons, C ^a   Bergoc, R ^a   Rivera, E ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE; HISTIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; BREAST CARCINOMA; CANCER INHIBITION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG MECHANISM; HISTAMINE BLOOD LEVEL; NONHUMAN; RAT; TUMOR GROWTH;

ANIMALS; CARCINOGENS; ENZYME INHIBITORS; FEMALE; HISTAMINE; HISTIDINE DECARBOXYLASE; MAMMARY NEOPLASMS, EXPERIMENTAL; METHYLHISTIDINES; METHYLNITROSOUREA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030909017     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000110050072     Document Type: Article

References (7)

1. Davio C, Cricco G, Bergoc R, Rivera E. H1 and H2 histamine receptors in experimental carcinomas with an atypical coupling to signal transducers. Biochem Pharmacol 1995;50:91-6.
2. Engel N, Cricco G, Davio C, Martin G, Croci M, Fitzsimons C, et al. Histamine regulates the expression of histidine decarboxylase in NMU-induced tumors in rats. Inflamm Res 1996;45:64-5.
3. Cricco G, Davio C, Fitzsimons C, Engel N, Bergoc R, Rivera E. Histamine as an autocrine growth factor in experimental carcinomas. Agents Actions 1994;43:17-20.
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6. Watanabe T, Yamatodani A, Maeyama K, Wada H. Pharmacology of β-fluoromethylhistidine, a specific inhibitor of histidine decarboxylase. Trends Pharmacol Sci 1990;11:363-7.
7. Maeyama K, Watanabe T, Taguchi Y, Yamatodani A, Wada H. Effect of α-fluoromethylhistidine, a suicide inhibitor of histidine decarboxylase, on histamine levels in mouse tissues. Biochem Pharmacol 1982;31:2367-70.