Assignment of the human connexin43 gene, GJA1, to chromosome 6q22.3

Japanese Journal of Human Genetics

Volumn 42, Issue 1, 1997, Pages 213-216

  Kato, Rumiko ^a   Matsumoto, Naomichi ^a   Niikawa, Norio ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

6q22.3; BAC clone; connexin43 gene; FISH; GJA1

Indexed keywords

GAP JUNCTION PROTEIN;

ARTICLE; CELL JUNCTION; CHROMOSOME 6Q; CONGENITAL HEART MALFORMATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE ASSIGNMENT; GENE MUTATION; HUMAN;

BACTERIA (MICROORGANISMS);

EID: 0030908452     PISSN: 09168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02766924     Document Type: Article

References (13)

1. Beyer ED, Paul D, Goodenough DA (1988): The connexins, a family of related gap junction proteins. In: Hertzberg EL, Johnson RG (eds). Gap junctions. A.R. Liss, New York, pp 167175
2. Britz-Cunningham SH, Shah MM, Zuppan CW, Fletcher WH (1995): Mutations of the connexM3 gap-junction gene in patients with heart malformations and defects of laterality. N Engl J Med 332: 1323-1329
3. Casey B, Ballabio A (1995): ConnexMS mutations in sporadic and familial defects of laterality. N Engl J Med 333: 941
4. Corcos I A, Meese EU, Loch-Caruso R (1993): Human connexin43 gene locus, CJAl, sublocalized to band 6q21-q23.2. Cytogenet Cell Genet 64: 31-32
5. Dutrillaux B, Viegas-Pequignot E (1981): High resolution R- and G-banding on the same preparation. Hum Genet 57: 93-95
6. Fishman GI, Eddy RL, Shows TB, Rosenthal L, Leinwand LA (1991): The human connexin gene family of gap junction proteins: distinct chromosomal locations but similar structures. Genomics 10: 250-256
7. Goshima K (1971): Synchronized beating of myocardial cells mediated by FL cells in monolayer culture and its inhibition by trypsin-treated FL cells. Exp Cell Res 65: 161-169
8. Hsieh C-L, Kumar NM, Gilula NB, Francke U (1991): Distribution of genes for gap junction membrane channel proteins on human and mouse chromosomes. Somatic Cell Mol Genet 17: 191-200
9. Kato R, Yamada Y, Niikawa N (1996): De novo balanced translocation (6;18)(q21;q21.3) in a patient with heterotaxia. Am J Med Genet 66: 184-186
10. Ohta T, Tohma T, Soejima H, Fukushima Y, Nagai T, Yoshiura K, Jinno Y, Niikawa N (1993): The origin of cytogenetically unidentifiable chromosome abnormalities: six cases ascertained by targeted chromosome-band painting. Hum Genet 92: 1-5
11. Penman Splitt M, Burn J, Goodship J (1995): Connex43 mutations in sporadic and familial defects of laterality. N Engl J Med 333: 941
12. Reaume AG, de Sousa PA, Kulkarni S, Langille BL, Zhu D, Davies TC, Juneja SC, Kidder GM, Rossant J (1995): Cardiac malformation in neonatal mice lacking connexin43. Science 267: 1831-1834
13. Willecke K, Jungbluth S, Dahl E, Hennemann H, Heynkes R, Grzeschik K-H (1990): Six genes of the human connexin gene family coding for gap junctional proteins are assigned to four different human chromosomes. Eur J Cell Biol 53: 275-280