Effect of bromfenac sodium (AHR-10282B) on postoperative inflammation - A double masked trial

Folia Ophthalmologica Japonica

Volumn 48, Issue 4, 1997, Pages 560-569

  Masuda, Kanjiro ^a,f   Fukado, Yoshinao ^b   Shimizu, Hiroyuki ^c   Usui, Masahiko ^d   Komemushi, Sadao ^e  

^a UNIVERSITY OF TOKYO   (Japan)

^b Miyota Central Memorial Hospital

^c JICHI MEDICAL UNIVERSITY   (Japan)

^d TOKYO MEDICAL UNIVERSITY   (Japan)

^e KINKI UNIVERSITY   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

Author keywords

A double masked trial; Bromfenac sodium; Inflammation following intraocular lens implantation; Non steroidal anti inflammatory drugs; Pranoprofen

Indexed keywords

BROMFENAC; PRANOPROFEN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CATARACT EXTRACTION; CLINICAL TRIAL; CONJUNCTIVA DISEASE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE INFECTION; SLIT LAMP; TOPICAL DRUG ADMINISTRATION; TREATMENT OUTCOME; UVEITIS;

EID: 0030908278     PISSN: 00155667     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. 2 inhibitor which prevents prostaglandin generation. Nature 278: 456-459, 1979.
2. Sancilio LF, Nolan JC et al: The analgesic and antiinflammatory activity and pharmacologic properties of brom-fenac. Arzneim-Forsch/Drug Res 37: 513-519, 1987.
3. Nolan JC, Wagner LE et al: The topical anti-inflammatory and analgesic properties of bromfenac in rodents. Agents & Actions 25: 77-85, 1988.
4. DeWitt DL: Prostaglandin endoperoxide synthase: Regulation of enzyme expression. Biochim Biophys Acta 1083: 121-134, 1991.
5. Sawa M, Tsurimaki Y et al: New quantitative method to determine protein concentration and cell number in aqueous in vivo. Jpn J Ophthalmol 32: 132-142, 1988.
6. Xie WL, Chipman JG et al: Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Nati Acad Sci USA 88: 2692-2696, 1991.
7. Hla T, Neilson K: Human cyclooxygenase-2 cDNA. Proc Natl Acad Sci USA 89: 7384-7388, 1992.
8. Mitchell JA, Akarasereenont P et al: Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 90: 11693-11697, 1993.
9. Unger WG: Review: Mediation of the ocular response to injury. J Ocul Pharmacol 6: 337-353, 1990.
10. Ford-Hutchinson AW, Bray MA et al: Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature 286: 264-265, 1980.