Control of oxygen cytotoxicity with allopurinol and superoxide dismutase: A canine model of global myocardial ischemia-reperfusion injury

Journal of Investigative Surgery

Volumn 10, Issue 1-2, 1997, Pages 63-68

  Qayumi, A K ^a   Jamieson, W R E ^a   Rosado, L J ^a   McConville, B ^a   Chow, V D W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Allopurinol; Global myocardial ischemia; Oxygen cytotoxicity; Superoxide dismutase

Indexed keywords

ALLOPURINOL; CARDIOPLEGIC AGENT; OXYGEN; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOPLEGIA; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; COVARIANCE; CYTOTOXICITY; DOG; ECHOCARDIOGRAPHY; HEART FUNCTION; HEART HEMODYNAMICS; HEART MUSCLE ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; SYSTOLIC BLOOD PRESSURE;

EID: 0030907716     PISSN: 08941939     EISSN: None     Source Type: Journal    
DOI: 10.3109/08941939709032128     Document Type: Article

References (17)

1. Burton KP, McCord JM, Ghai G. Myocardial alterations due to free radical generation. Am J Physiol. 1984;246:H776-H783.
2. Menasche P, Piwnica A. Free radicals and myocardial protection: a surgical viewpoint. Ann Thorac Surg. 1989;47:939-945.
3. Menasche P, Grousset C, Gouduely M, Piwnica A. Prevention of hydroxyl radical formation: a critical concept for improving cardioplegia. Circulation. 1987;76(Pt 2):V2-V180.
4. Meerson RZ, Kagan VE, Lozlov YP, Belkina LM, Arkhipenko YV. The role of lipid peroxidation in pathogenesis of ischemic damage and antioxidant status of the heart. Basic Res Cardiol. 1982;77:465.
5. Godin DV, Bhimji S, McNeill JH. Effects of allopurinol pretreatment on myocardial ultrastructure and arrythmias following coronary artery occlusion and reperfusion. Virchows Arch [B]. 1986;52:327-341.
6. Myers ML, Bolli R, Lekich RF, Hartley CJ, Roberts, R. Enhancement of recovery of myocardial function by oxygen free radical scavengers after reversible regional ischemia. Circulation. 1985;72:915-921.
7. Myers CL, Weiss SJ, Kirsh MM, Shepard BM, Shlafer M, Mich AA. Effects of supplementing hypothermic crystalloid cardioplegic solution with catalase, superoxide dismutase, allopurinol, or desferoxamine on functional recovery of globally ischemic and reperfused isolated hearts. J Thorac Cardiovasc Surg. 1986;91:281-289.
8. Shlafer M, Kane PF, Kirsh MM, Mich AA. Superoxide dismutase pluse catalase enhances the efficacy of hypothermic cardioplegia to protect the globally ischemic, reperfused heart. J Thorac Cardiovasc Surg. 1982;83:830-839.
9. Stewart JR, Blackwell WH, Crute SL, Loughlin V, Greenfield LJ, Hess ML. Inhibition of surgically induced ischemia/reperfusion injury by oxygen free radical scavengers. J Thorac Cardiovasc Surg. 1983;86:262-272.
10. Otani H, Umemoto M, Kagawa K, et al. Protection against oxygen-induced reperfusion injury of the isolated canine heart by superoxide dismutase and catalase. J Surg Res. 1986;41:126-133.
11. Otani H, Engelman RM, Rousou JA, Breyer RH, Lemeshow S, Das DK. Cardiac performance during reperfusion improved by pretreatment with oxygen free-radical scavengers. J Thorac Cardiovasc Surg. 1986; 91:290-295.
12. Douglas PS, Reichek N, Plappert T, Muhammad A, St. John Sutton MG. Comparison of echocardiographic methods for assessment of left ventricular shortening and wall stress. J Am Coll Cardiol. 1987; 9:945-951.
13. DeWall RA, Vasko KA, Stanley EL, Kezdi P. Responses of the ischemic myocardium to allopurinol. Am Heart J. 1971;82:362-370.
14. Stewart JR, Crute SL, Loughlin V, Hess ML, Greenfield LJ. Prevention of free radical-induced myocardial reperfusion injury with allopurinol. J Triorac Cardiovasc Surg. 1985;90:68-72.
15. Eddy LJ, Stewart JR, Jones HP, Engerson TD, McCord JM, Downey JM. Free radical-producing enzyme, xanthine oxidase, is undetectable in human hearts. Am J Physiol. 1987;235:H709-H711.
16. Das DK, Engelman RM, Rousou JA, Breyer RH, Otani H, Lemeshow S. Pathophysiology of superoxide radical as potential mediator of reperfusion. Basic Res Cardiol. 1986;81:155-166.
17. Qayumi AK, Jamieson WRE, Godin DV, et al. Response to allopurinol pretreatment in a swine model of heart-lung transplantation. J Invest Surg. 1990;3:331-340.