Serial analysis of autoantibody responses to the collagen-like region of Clq, collagen type II, and double stranded DNA in patients with systemic lupus erythematosus

Journal of Rheumatology

Volumn 24, Issue 5, 1997, Pages 871-878

  Sjoholm, Anders G ^a   Martensson, Ulla ^b   Sturfelt, Gunnar ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

AUTOIMMUNITY; COLLAGEN TYPE II; COMPLEMENT PROTEIN Clq; HYPOCOMPLEMENTEMIA; NATIVE DNA; SYSTEMIC LUPUS ERYTHEMATOSUS

Indexed keywords

AUTOANTIBODY; COLLAGEN TYPE 2;

ADULT; ANTIBODY RESPONSE; ARTICLE; CLINICAL ARTICLE; COLLAGEN DISEASE; DATA ANALYSIS; DISEASE ASSOCIATION; DISEASE SEVERITY; DNA DETERMINATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HYPOCOMPLEMENTEMIA; LUPUS ERYTHEMATOSUS NEPHRITIS; MALE; PATIENT CARE; PATIENT MONITORING; PRIORITY JOURNAL; STATISTICAL ANALYSIS; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANTIBODIES, ANTINUCLEAR; ANTIBODY SPECIFICITY; AUTOANTIBODIES; COLLAGEN; COMPLEMENT C1Q; CROSS REACTIONS; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; PROSPECTIVE STUDIES; PROTEIN STRUCTURE, TERTIARY;

EID: 0030907590     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Antes U, Heinz H-P, Loos M: Evidence for the presence of autoantibodies to the collagen-like portion of Clq in systemic lupus erythematosus. Arthritis Rheum 1988;31:457-64.
2. Uwatoko S, Mannik M: Low-molecular weight Clq-binding immunoglobulin G in patients with systemic lupus erythematosus consists of autoantibodies to the collagen-like portion of Clq. J Clin Invest 1988;82:816-24.
3. Wisnieski JJ, Naff GB: Serum IgG antibodies to Clq in hypocomplementemic urticarial vasculitis syndrome. Arthritis Rheum 1989;32:1119-27.
4. Wisnieski JJ, Baer AN, Christensen J, et al: Hypocomplementemic urticarial vasculitis syndrome. Clinical and serologic findings in 18 patients. Medicine (Baltimore) 1995;74:24-41.
5. Mårtensson U, Sjöholm AG, Sturfelt G, Truedsson L, Laurell A-B: Western blot analysis of human IgG reactive with the collagenous portion of Clq: Evidence of distinct binding specificities. Scand J Immunol 1992;35:735-44.
6. Siegert CEH, Daha MR, van der Voort EAM, Breedveld FC: IgG and IgA antibodies to the collagen-like region of Clq in rheumatoid vasculitis. Arthritis Rheum 1990;33:1646-54.
7. Strife CF, Leahy AE, West CD: Antibody to a cryptic, solid phase Clq antigen in membranoproliferative nephritis. Kidney Int 1989;35:836-42.
8. Coremans IEM, Daha MR, van der Voort EAM, Muizert Y, Halma C, Breedveld FC: Antibodies against Clq in antiglomerular basement membrane nephritis. Clin Exp Immunol 1992;87:256-60.
9. Morgan K: What do anti-collagen antibodies mean? Ann Rheum Dis 1990;49:62-5.
10. Choi EKK, Gatenby PA, Bateman JF, Cole WG: Antibodies to type II collagen in SLE: A role in the pathogenesis of deforming arthritis? Immunol Cell Biol 1990;68:27-31.
11. Moreland LW, Gay RE, Gay S: Collagen autoantibodies in patients with vasculitis and systemic lupus erythematosus. Clin Immunol Immunopathol 1991;60:412-8.
12. Wener MH, Uwatoko S, Mannik M: Antibodies to the collagen-like region of Clq in sera of patients with autoimmune rheumatic diseases. Arthritis Rheum 1989;32:544-51.
13. Siegert CEH, Daha MR, Westedt M-L, van der Voort E, Breedveld F: IgG autoantibodies against Clq are correlated with nephritis, hypocomplementemia, and dsDNA antibodies in systemic lupus erythematosus. J Rheumatol 1991;18:230-4.
14. Wisnieski JJ, Jones SM: IgG autoantibody to the collagen-like region of Clq in hypocomplementemic urticarial vasculitis syndrome, systemic lupus erythematosus, and 6 other musculoskeletal or rheumatic diseases. J Rheumatol 1992;19:884-8.
15. Aarden LA, de Groot ER, Feltkamp TEW: Immunology of DNA. III. Crithidia luciliae, a simple substrate for the determination of anti-dsDNA with the immunofluorescence technique. Ann NY Acad Sci 1975;254:505-15.
16. Emlen W, Jarusiripipat P, Burdick G: A new ELISA for the detection of double-stranded DNA antibodies. J Immunol Methods 1990;132:91-101.
17. Siegert CEH, Daha M, Tseng CMES, Coremans IEM, van Es LA, Breedveld FC: Predictive value of IgG autoantibodies against Clq for nephritis in systemic lupus erythematosus. Ann Rheum Dis 1993;52:851-6.
18. Lloyd W, Schur PH: Immune complexes, complement, and anti-DNA in exacerbations of systemic lupus erythematosus. Medicine (Baltimore) 1981;60:208-17.
19. Swaak AJG, Groenwold J, Bronsweld W: Predictive value of complement profiles and anti-dsDNA in systemic lupus erythematosus. Ann Rheum Dis 1986;45:359-66.
20. Heinz H-P, Rubin K, Laurell A-B, Loos M: Common epitopes in Clq and collagen type II. Mol Immunol 1989;26:163-9.
21. Maeurer MJ, Trinder PKE, Störkel S, Loos M: Clq in autoimmune diseases: Rheumatoid arthritis. Behring Inst Mitt 1993;93:262-78.
22. Eilat D: Cross-reactions of anti-DNA antibodies and the central dogma of lupus nephritis. Immunol Today 1985;6:123-7.
23. Bach J-F, Viard J-P: Cellular and genetic mechanisms at the origin of systemic lupus erythematosus: A unifying hypothesis. In: Lydyard PM, Brostoff J, eds. Autoimmune Disease. Aetiopathogenesis, Diagnosis and Treatment. Oxford: Blackwell Science Ltd., 1994:105-18.
24. Sturfelt G, Sjöholm AG: Complement components, complement activation, and acute phase response in systemic lupus erythematosus. Int Archs Allergy Appl Immunol 1984;75:75-83.
25. Sturfelt G, Johnson U, Sjöholm AG: Sequential studies of complement activation in systemic lupus erythematosus. Scand J Rheumatol 1985;14:184-96.
26. Jonsson H, Nived O, Sturfelt G: Outcome in systemic lupus erythematosus: A prospective study of patients from a defined population. Medicine (Baltimore) 19849;68:141-50.
27. Bombardier C, Gladman DD, Urowitz BM, Chang C, Charron D: Development and validation of the SLEDAI: An index of disease activity in SLE. Arthritis Rheum 1992;35:630-40.
28. Mårtensson U, Thiel S, Jensenius JC, Sjöholm AG: Human antibodies against Clq: Lack of cross-reactivity with the collectins mannan-binding protein, lung surfactant protein A and bovine conglutinin. Scand J Immunol 1996;43:314-20.
29. Reid KBM: Isolation, by partial pepsin digestion, of the three collagen-like regions present in subcomponent Clq of the first component of human complement. Biochem J 1976;155:5-17.
30. Klareskog L, Forsum U, Scheynius A, Kabelitz D, Wigzell H: Evidence in support of a self-perpetuating HLA-DR-dependent delayed-type cell reaction in rheumatoid arthritis. Proc Natl Acad Sci USA 1982;79:3632-6.
31. Voller A, Bidwell DE, Bartlett A: Enzyme immunoassays in diagnostic medicine. Bull WHO 1976;53:55-65.
32. Johnson U, Truedsson L, Gustavii B: Complement components in 100 newborns and their mothers determined by electroimmunoassay. Acta Pathol Microbiol Immunol Scand (C) 1983;91:147-50.
33. Cooper NR: Laboratory investigation of complement proteins and complement receptors. Bailliere's Clin Immunol Allergy 1988;2:263-93.
34. Siegel S, Castellan NJ: Nonparametric Statistics for the Behavioral Sciences. 2nd ed. McGraw Hill International Editions, 1988.
35. Holmskov U, Malhotra R, Sim RB, Jensenius JC: Collectins: Collagenous C-type lectins of the innate immune defense system. Immunol Today 1994;15:67-73.
36. Tarkowski A, Bjursten LM, Nilsson L-Å, Nygren H: False positive results in class-specific rheumatoid factor (RF) assays due to interaction between RF and Fc fragments of anti-immunoglobulin indicator reagents. J Immunol Methods 1983;58:171-82.
37. Smeenk R, van der Lelij G, Aarden L: Avidity of antibodies to dsDNA: Comparison of IFT on Crithidia luciliae, Fair assay, and PEG assay. J Immunol 1982;128:73-8.
38. Clague RB, Firth SA, Holt PJ, Skingle J, Greenbury CL, Webley M: Serum antibodies to type II collagen in rheumatoid arthritis: Comparison of 6 immunological methods and clinical features. Ann Rheum Dis 1983;42:537-44.
39. Iribe H, Kabashima H, Ishii Y, Koga T: Epitope specificity of antibody response against human type II collagen in the mouse susceptible to collagen-induced arthritis and patients with rheumatoid arthritis. Clin Exp Immunol 1988;73:443-8.
40. Rowley MJ, Mackay IR, Brand CA, Bateman JF, Chan D: Epitope specificity of antibodies to type II collagen in rheumatoid arthritis and systemic lupus erythematosus. Rheumatol Int 1992;12:65-9.
41. Huang S-C, Pan Z, Kurien BT, James JA, Harley JB, Scofield RH: Immunization with vesicular stomatitis virus nucleocapsid protein induces autoantibodies to the 60 kD Ro ribonucleoprotein particle. J Investig Med 1995;43:151-8.
42. Jonsson H, Sturfelt G, Mårtensson U, Truedsson L, Sjöholm AG: Prospective analysis of C1 dissociation and complement activation in patients with systemic lupus erythematosus; Clin Exp Rheumatol 1995;13:573-80.
43. Gewurz H, Yng S-C, Jiang H, Lint TF: Nonimmune activation of the classical complement pathway. Behring Inst Mitt 1993;93:138-47.
44. Claus DR, Siegel J, Petras K, Skor D, Osmand AP, Gewurz H: Complement activation by interaction of polyanions and polycations. III. Complement activation by interaction of multiple polyanions and polycations in the presence of C-reactive protein. J Immunol 1977;188:83-7.