Role of nuclear magnetic resonance spectroscopy (MRS) in cancer diagnosis and treatment: 31P, 23Na, and 1H MRS studies of three models of pancreatic cancer

Cancer Research

Volumn 57, Issue 8, 1997, Pages 1452-1459

  Kaplan, Ofer ^a   Kushnir, Tammar ^a   Askenazy, Nadir ^a   Knubovets, Tatyana ^a   Navon, Gil ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; PHOSPHORUS 31; SODIUM 23;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CHEMOTHERAPY; DIAGNOSTIC VALUE; DRUG EFFICACY; DRUG SENSITIVITY; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; NONHUMAN; PANCREAS CANCER; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; TREATMENT PLANNING;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ADENOCARCINOMA, PAPILLARY; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOGENS; CRICETINAE; DEOXYGLUCOSE; HUMANS; INDAZOLES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MESOCRICETUS; NEOPLASM TRANSPLANTATION; PANCREATIC NEOPLASMS; PHOSPHORUS; PROTONS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; TUMOR CELLS, CULTURED;

EID: 0030907466     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. American Cancer Society. Cancer Facts and Figures 1991. Atlanta: American Cancer Society, 1991.
2. Warshaw, A. L., and Castillo, C. F. Pancreatic carcinoma. N. Engl. J. Med., 326: 455-465, 1992.
3. National Cancer Institute. Annual Cancer Statistics Review 1973-1988, NIH publication no. 91-2789. Bethesda, MD: Department of Health and Human Services, 1991.
4. Gadian, D. G. Nuclear Magnetic Resonance and its Application to Living Systems, pp. 1-170. New York: Oxford University Press, 1982.
5. Kaplan, O., van Zijl, P. C. M., and Cohen, J. S. NMR spectroscopy of metabolism in cells and perfused organs. In: R. Stumpe and S. Seelig (eds.), In Vivo Magnetic Resonance Spectroscopy, Vol. 28, pp. 3-54. Berlin: Springer-Verlag, 1992.
6. Daly, P. F., and Cohen, J. S. Magnetic resonance spectroscopy of tumors and its potential in vivo applications: a review. Cancer Res., 49: 770-779, 1989.
7. Kaplan, O., and Cohen, J. S. Metabolism of breast cancer cells as revealed by non-invasive magnetic resonance spectroscopy studies. Breast Cancer Res. Treat., 31: 285-299, 1994.
8. Kaplan, O., Navon, G., Lyon, R. C., Faustino, P. J., Straka, E. J., and Cohen, J. S. Effects of 2-deoxyglucose on drug-sensitive and drug-resistant breast cancer cells: toxicity and magnetic resonance spectroscopy studies of metabolism. Cancer Res., 50: 544-551, 1990.
9. 13C NMR studies. Cancer Res., 55: 2814-2821, 1995.
10. 31P magnetic resonance spectroscopy for monitoring treatment response in breast cancer. Lancet, 1: 1326-1327, 1989.
11. 31P MRS in situ. Magn. Reson. Med., 10: 125-134, 1989.
12. 31P magnetic resonance spectroscopy profiles of neoplastic human breast tissues. Cancer Res., 48: 5112-5118, 1988.
13. Negendank, W. G., Crowly, M. G., Ryan, J. P., Keller, N. A., and Evelhoch, J. L. Bone and soft tissue lesions: diagnosis with combined H-1 MR imaging and P-31 MR spectroscopy. Radiology, 173: 181-188, 1989.
14. Su, B., Kappler, F., Szwergold, B. S., and Brown, T. R. Identification of a putative tumor marker in breast and colon cancer. Cancer Res., 53: 1751-1754, 1993.
15. Mountford, C. E., and Tattersall, M. H. N. Proton magnetic resonance spectroscopy and tumour detection. Cancer Surv., 6: 285-314, 1987.
16. Fossel, E. T., Can, J. M., and McDonagh, J. Detection of malignant tumors. Water-suppressed proton nuclear magnetic resonance spectroscopy of plasma. N. Engl. J. Med., 315: 1369-1376, 1986.
17. Shulman, R. G. NMR: another cancer-test disappointment. N. Engl. J. Med., 322: 1002-1003, 1990.
18. 31P nuclear magnetic resonance characterization and 2-deoxyglucose toxicity. Cancer Res., 57: 1638-1644, 1991.
19. 31P NMR of mammalian cells encapsulated in alginate gels utilizing a new phosphate-free perfusion medium. NMR Biomed., 3: 23-26, 1990.
20. 31P magnetic resonance studies. J. Biol. Chem., 266: 3688-3694, 1991.
21. Alley, M. C., Scudiero, D. A., Hursey, M. L., Czerwinsky, M. J., Fine, D. L., Abbot, B. J., Mayo, J. G., Shoemaker, R. H., and Boyd, M. R. Feasibility of drug screening with panels of human tumor cells lines using a microculture tetrazolium assay. Cancer Res., 48: 589-601, 1988.
22. Lowry, O. H., and Passonneau, J. V. A. A Flexible System of Enzymatic Analysis, pp. 12-124. New York: Academic Press, 1972.
23. 31P correlation NMR study. NMR Biomed., 3: 220-226, 1990.
24. 31P nuclear magnetic resonance studies of Ehrlich ascites tumor cells. Proc. Natl. Acad. Sci. USA, 74: 87-91, 1977.
25. 13C resonances, Biochim. Biophys. Acta, 805: 104-116, 1984.
26. Kaplan, O., Kushnir, T., Sandbank, U., and Navon, G. 31P nuclear magnetic resonance studies of experimental pancreatitis in rats. J. Surg. Res., 43: 172-178, 1987.
27. Kaplan, O., Kushnir, T., and Navon, G. 31P nuclear magnetic resonance studies of perfused rat pancreas and experimental pancreatitis. Res. Surg., in press, 1997.
28. Guidoni, L., Marietti, G., Rampelli, G. M., Rosi, A., and Viti, V. Mobile phospholipid signals in NMR spectra of cultured human adenocarcinoma cells. Magn. Reson. Med., 5: 578-585, 1987.
29. Cameron, I. L., Smith, N. K. R., Pool, T. B., and Sparks, R. L. Intracellular concentration of sodium and other elements as related to mitogenesis and oncogenesis in vivo. Cancer Res., 40: 1493-1500, 1980.
30. 31P NMR studies of extracts: differences between drug-sensitive and resistance MCF-7 breast cancer cells. Biochem. Biophys. Res. Commun., 169: 383-390, 1990.
31. 13C nuclear magnetic resonance studies. Breast Cancer Res. Treat., in press, 1997.
32. Scarpelli, D. G., and Rao, M. S. Transplantable ductal adenocarcinoma of the Syrian hamster pancreas. Cancer Res., 39: 452-458, 1979.
33. Sindelar, W. F., and Kurman, C. C. Nitrosamine-induced pancreatic carcinogenesis in outbred and inbred Syrian hamsters. Carcinogenesis (Lond.), 3: 1021-1026, 1982.
34. Satake, K., Mukai, R., Kato, Y., Shim, K., and Umeyama, K. Experimental pancreatic carcinoma as a model of human pancreatic carcinoma. Clin. Oncol., 10: 27-34, 1984.
35. Dissin, J., Mills, L. R., Mains, D. L., Black, O., and Webster, P. D., Experimental induction of pancreatic adenocarcinoma in rats. J. Natl. Cancer Inst., 55: 857-864, 1975.
36. Oberhaensli, R. D., Bore, P. J., Rampling, R. P., Hilton-Jones, D., Hands, L. J., and Radda, G. K. Biochemical investigation of human tumours in vivo with phosphorous-31 magnetic resonance spectroscopy. Lancet, 1: 8-11, 1986.
37. 31P MRS study. Br. J. Cancer, 67: 1145-1153, 1993.
38. 13C-NMR spectroscopy study. Cancer Res., 55: 5140-5145, 1995.
39. 31P-NMR saturation transfer study of the regulation of creatine kinase in the rat heart. Biochim. Biophys. Acta, 721: 312-320, 1982.
40. Cone, C. D., Jr. Electroosmotic interactions accompanying mitosis initiation in sarcoma cells in vitro. Trans. NY Acad. Sci., 31: 404-427, 1969.
41. Goldsmith, M., and Damadian, R. NMR in cancer. VII. Sodium-23 magnetic resonance of normal and cancerous tissues. Physiol. Chem. Phys., 7: 263-269, 1975.
42. Stubbs, M., Rodrigues, L., Howe, F. A., Wang, J., Jeong, K-S., Veech, R. L., and Griffiths, J. R. Metabolic consequences of a reversed pH gradient in rat tumors. Cancer Res., 54: 4011-4016, 1994.
43. 23 Na NMR spectroscopy. Ann. NY Acad. Sci., 508: 149-161, 1987.
44. Griffey, R. H., Griffey, B. V., and Matwiyoff, N. A. Triple-quantum-coherencefiltered imaging of sodium ions in vivo at 4.7 tesla. Magn. Reson. Med., 13: 305-313, 1990.
45. Hilal, S. K., Maudsley, A. A., Ra, J. B., Simon, H. E., Roschmann, P., Wittekoek, G., Cho, Z. H., and Mun, S. K. In vivo NMR imaging of sodium-23 in the human head. J. Comput. Assist. Tomogr, 9: 1-7, 1985.
46. Turski, P. A., Houston, L. W., Perman, W. H., Hald, J. K., Turski, D., Strother, C. M., and Sackett, J. F. Experimental and human brain neoplasms: detection with in vivo sodium MR imaging. Radiology, 163: 245-249, 1987.
47. 23Na NMR studies of experimental pancreatitis. NMR Biomed., 4: 182-186, 1991.
48. 1H NMR spectroscopy. Pancreas, 4: 145-152, 1989.
49. Smith, I. C. P., and Chmurny, G. N. NMR spectroscopy and research: the present and the future. Anal. Approach, 62: 853A, 1990.
50. 1H MRS. In: J. D. De Certaines (ed.), Magnetic Resonance Spectroscopy of Biofluids - A New Tool in Clinical Biology, pp. 103-118. London: World Scientific Publishing Co., 1989.
51. 1H COSY spectra of plasma membrane fragments shed from human colorectal cells. Magn. Reson. Med., 20: 306-311, 1991.
52. Geggel, H. S., Ament, M. E., Heckenlively, J. R., Martin, D. A., and Kopple, J. D. Nutritional requirement for taurine in patients receiving long-term parenteral nutrition. N. Engl. J. Med., 312: 142-146, 1985.
53. Wright, C. E., Tallan, H. H., and Yong, Y. L. Taurine: biological update. Ann. Rev. Biochim., 55: 427-453, 1986.
54. Roberts, E., and Frankel, S. Free amino acids in normal and neoptastic tissues of mice as studied by paper chromatography. Cancer Res., 9: 645-648, 1949.
55. 1H NMR spectroscopy of colon tumors and normal mucosal biopsies: elevated taurine levels and reduced polyethyleneglycol absorption in tumors may have diagnostic significance. NMR Biomed., 6: 111-118, 1993.
56. Remy, C., Arus. C., Ziedler, A., Lai, E. S., Moreno, A., Le-Fur, Y., and Decorps, M. In vivo, ex vivo, and in vitro one-and two-dimensional nuclear magnetic resonance spectroscopy of an intracerebral glioma in rat brain: assignment of resonances. J. Neurochem., 62: 166-179, 1994.
57. Kinoshita, Y., Kajiwara, H., Yokota, A., and Koga, Y. Proton magnetic resonance spectroscopy of brain tumors: an in vitro study. Neurosurgery, 35: 606-613, 1994.
58. Chemin-Thomas, C., Palevody, C., Esclassan, J., and Hollande, E. Combined magnetic resonance imaging and spectroscopy for characterization of human pancreatic adenocarcinoma (Capan-1) heterotransplanted in nude mice. Gastroenterol, Clin. Biol., 18: 859-864, 1994.
59. Podo, F., Carpinelli, G., Di vito. M., Giannini, M., Proietti, E., Fiers, W., Gresser, I., and Belardelli, F. Nuclear magnetic resonance analysis of tumor necrosis factor-induced alterations of phospholipid metabolites and pH in Friend leukemia cell tumors and fibrosarcoma in mice. Cancer Res., 47: 6481-6489, 1987.
60. Jiang, X. R., Yang, M., Morris, C. J., Newland, A. C., Naughton, D. P., Blake, D. R., Zhang, Z., and Grootveld, M. C. High field proton NMR investigations of the metabolic profiles of multidrug-sensitive and -resistant leukemic cell lines: evidence for diminished taurine levels in multidrug-resistant cells. Free Radical Res. Commun., 19: 355-369, 1993.
61. Moscow, J. A., and Cowan, K. H. Multidrug resistance. J. Natl. Cancer Inst., 80: 14-20, 1988.