Specific activation of resting T cells against tumour cells by bispecific antibodies and CD28-mediated costimulation is accompanied by Th1 differentiation and recruitment of MHC-independent cytotoxicity

Clinical and Experimental Immunology

Volumn 108, Issue 2, 1997, Pages 352-357

  Hombach, A ^a   Tillmann, T ^a   Jensen, M ^a   Heuser, C ^a   Sircar, R ^a   Diehl, V ^a   Kruis, W ^b   Pohl, C ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b Evangelisches Krankhs Koln Kalk   (Germany)

Author keywords

adoptive immunotherapy; bispecific antibodies; cytokine network; T cell immunology; tumour targeting

Indexed keywords

BISPECIFIC ANTIBODY; CA 19-9 ANTIGEN; CD16 ANTIGEN; CD28 ANTIGEN; CYTOKINE; GAMMA INTERFERON; GLUTARALDEHYDE; INTERLEUKIN 10; INTERLEUKIN 2; MONOCLONAL ANTIBODY; OKT 3; PHYTOHEMAGGLUTININ;

ADOPTIVE IMMUNOTHERAPY; ARTICLE; CANCER CELL CULTURE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOLYSIS; DRUG TARGETING; EFFECTOR CELL; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOKINE ACTIVATED KILLER CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; NATURAL KILLER CELL; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0030906966     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1997.3481245.x     Document Type: Article

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