Stereoselective determination of a new antidepressant, E2011, and its diastereoisomer as a metabolite by high-performance liquid chromatography

Journal of Chromatography B: Biomedical Applications

Volumn 694, Issue 1, 1997, Pages 153-161

  Naitoh, T ^a   Kakiki, M ^a   Kawaguchi, S ^a   Kagei, Y ^a   Horie, T ^a  

^a EISAI CO LTD   (Japan)

Author keywords

E2011; Enantiomer separation; ER 2059

Indexed keywords

3 [2 (3 CYANO 1 HYDROXYPROPYL) 6 BENZOTHIAZOLYL] 5 METHOXYMETHYL 2 OXAZOLIDINONE; ANTIDEPRESSANT AGENT; DRUG METABOLITE; ER 2059; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DIASTEREOISOMER; DRUG BLOOD LEVEL; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIDEPRESSIVE AGENTS; BENZOTHIAZOLES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; MALE; MONOAMINE OXIDASE INHIBITORS; OXAZOLES; OXAZOLIDINONES; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM; THIAZOLES;

EID: 0030906323     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(97)00111-4     Document Type: Article

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