Evaluation of a decision support system for initiation and control of oral anticoagulation in a randomised trial

British Medical Journal

Volumn 314, Issue 7089, 1997, Pages 1252-1256

  Vadher, B ^a   Patterson, D L H ^a   Leaning, M ^b  

^a WHITTINGTON HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; WARFARIN;

ADOLESCENT; ADULT; AGED; ANTICOAGULATION; ARTICLE; CLINICAL TRIAL; COMPUTER SYSTEM; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL DECISION MAKING; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; UNITED KINGDOM;

EID: 0030905412     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.314.7089.1252     Document Type: Article

References (24)

1. Duxbury BMcD. Therapeutic control of anticoagulant treatment. BMJ 1982;284:702-4.
2. Majumder G, Payne RW. Quality of oral anticoagulant therapy. Clin Lab Haematol 1985;7:125-31.
3. Doble N, Baron JH. Anticoagulation control with warfarin by junior doctors. J R Soc Med 1987;80:627.
4. Tan G, Cohen H, Taylor F, Gabbay J. Audit of start of anticoagulation treatment in inpatients. J Clin Path 1993;46:67-71.
5. Rose PE. Audit of oral anticoagulant treatment. J Clin Pathol 1993;46:1069-70.
6. Holford NHG. Clinical pharmacokinetics and pharmacodynamics of warfarin - Understanding the dose-effect relationship. Clin Pharmacokinet 1986;11:483-504.
7. Fennerty A, Dolbert J, Thomas P, Backhouse G, Bentley DP, Campbell IA, et al. Flexible induction dose regimen for warfarin and prediction of maintenance dose. BMJ 1984;288:1268-70.
8. How to anticoagulate. Drug Ther Bull 1992;30:77-80.
9. Doecke CJ, Cosh DG, Gallus AS. Standardised initial warfarin treatment: evaluation of initial treatment response and maintenance dose prediction by randomised trial, and risk factors for an excessive warfarin response. Aust N Z J Med 1991;21:319-24.
10. Poller L, Wright D, Rowlands M. Prospective comparative study of computer programs used for management of warfarin. J Clin Pathol 1993;46:299-303.
11. White RH, Hong R, Venook A, Daschbach MM, Murray W, Mungall DR, et al. Initiation of warfarin therapy: comparison of physician dosing with computer assisted dosing. J Gen Intern Med 1987;2:141-8.
12. White RH, Mungall DR. Outpatient management of warfarin therapy: comparison of computer-predicted dose adjustment to skilled professional care. Ther Drug Monit 1991;13:46-50.
13. Vozch S, Steiner JL. Feedback control mechanisms for drug dosage optimisation: concepts, classification and clinical application. Clin Pharmacokinet 1985;10:457-76.
14. Vadher B, Patterson DLH, Leaning M. Prediction of INR and maintenance dose during initiation of warfarin therapy using a Bayesian pharmacokinetic/pharmacodynamic model. Br J Haematol 1996;93 (suppl 1):30.
15. Vadher BD, Patterson DLH, Leaning MS. Validation of an algorithm for oral anticoagulant dosing and appointment scheduling. Clin Lab Haematol 1993;17:339-45.
16. Altman D. Practical statistics for medical research. London: Chapman and Hall, 1991.
17. Lewis SM. External quality assessment. In: Lewis SM, Verwilghen RL, eds. Quality assurance in haematology. London: Balliére Tindall, 1988:154-75.
18. Department of Health. Anticoagulant treatment. London: HMSO, 1985.
19. Rosendaal FR, Cannegieter SC, van der Meer FJM, Briet E. A method to determine the optimal intensity of oral anticoagulant therapy. Thromb Haemost 1993;69:236-9.
20. Glynn RJ, Buring JE. Ways of measuring rates of recurrent events. BMJ 1996;312:364-7.
21. Stukel TA, Glynn RJ, Fisher ES, Sharp SM, Lu-Yao G, Wennberg JE. Standardised rates of recurrent events. Stat Med 1994;13:1781-91.
22. Abbrecht PH, Timothy JO, Behrendt DM. Evaluation of a computer-assisted method for individualized anticoagulation: retrospective and prospective studies with a pharmacodynamic model. Clin Pharmacol Ther 1982;32:129-36.
23. Carter BL, Taylor JW, Becker A. Evaluation of three dosage-prediction methods for initial in-hospital stabilization of warfarin therapy. Clin Pharmacol 1987;6:37-45.
24. Fitzmaurice DA, Hobbs FDR, Murray JA. Monitoring oral anticoagulation in primary care. BMJ 1996;312:1431-2.