One-week therapy with omeprazole, clarithromycin and amoxycillin: High efficacy in eradicating Helicobacter pylori and healing duodenal ulcer;Tratamiento con omeprazol, claritromicina y amoxicilina durante una semana: Elevada eficacia en la erradicacion de Helicobacter pylori y en la cicatrizacion de la ulcera duodenal

Medicina Clinica

Volumn 108, Issue 14, 1997, Pages 524-529

  Gisbert, J P ^a,c   Mur, M ^a   Boixeda, D ^a   Cena G ^a   Martin De Argila C ^a   Alvarez Baleriola I ^b   Abraira, V ^a   Garcia Plaza A ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

^b Hospital de Catatayud   (Spain)

^c NONE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; CLARITHROMYCIN; OMEPRAZOLE;

ADULT; ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; DUODENUM ULCER; FEMALE; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; MALE; ORAL DRUG ADMINISTRATION;

ADULT; AMOXICILLIN; ANTI-BACTERIAL AGENTS; ANTI-ULCER AGENTS; CHRONIC DISEASE; CLARITHROMYCIN; DRUG THERAPY, COMBINATION; DUODENAL ULCER; FEMALE; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OMEPRAZOLE; PENICILLINS; PROSPECTIVE STUDIES; TIME FACTORS; WOUND HEALING;

EID: 0030905381     PISSN: 00257753     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (62)

1. NIH, Consensus Conference. Helicobacter pylori in peptic ulcer disease. JAMA 1994; 272: 65-69.
2. Chiba N, Rao BV, Rademaker JW, Hunt RH. Meta-analysis of the efficacy of antibiotic therapy in eradicating Helicobacter pylori. Am J Gastroenterol 1992; 87: 1.716-1.722.
3. Bell GD, Powell KU, Burridge SM. Experience with «triple» anti-H. pylori eradication therapy: side effects and importance of testing the pretreatment bacterial isolate for metronidazole resistance. Aliment Pharmacol Ther 1992; 6: 427-431.
4. Labenz J, Gyenes E, RühI GH, Börsch G. Amoxicillin plus omeprazole versus triple therapy for eradication of Helicobacter pylori in duodenal ulcer disease: a prospective, randomized, and controlled study. Gut 1993; 34: 1.167-1.170.
5. Logan RPH, Gummett PA, Schaufelberger HD, Greaves RRFH, Mendelson GM, Walker MM et al. Eradication of Helicobacter pylori with clarithromycin and omeprazole. Gut 1994; 35: 323-326.
6. Gisbert JP, Mur M, Sáinz S, Ceña G, Martín C, Sáinz Samitier R et al. ¿Es útil la asociación de omeprazol y amoxicilina en el tratamiento erradicador de Helicobacter pylori en España? Rev Esp Enf Digest 1996; 80: 99-106.
7. Treiber G. The influence of drug dosage on Helicobacter pylori eradication: a cost-effectiveness analysis. Am J Gastroenterol 1996; 91: 246-257.
8. Belsley DA. Conditioning diagnostics: collinearity and weak data in regression. Nueva York: John Wiley & Sons, 1991.
9. Bode G, Malfertheiner P. The influence of omeprazole on growth, morphology and viability of Helicobacter pylori in vitro. Ital J Gastroenterol 1991; 23 (Supl 2): 35-38.
10. Kuipers EJ, Klinkenberg-Knol EC, Festen HPM, Lamers CBHW, Jansen JBMJ, Snel P et al. Long-term omeprazole therapy does not affect Helicobacter pylori status in most patients. Scand J Gastroenterol 1993; 28: 978-980.
11. Wilde MI, McTavish D. Omeprazole: an update of its pharmacology and therapeutic use in acid-related disorders. Drugs 1994; 48: 91-132.
12. De Koster E, Nyst JF, Deprez C, Glupcynski Y, Jonas C, Denis P et al. Helicobacter pylori treatment: disappoiting results with amoxicillin plus omeprazole. Ital J Gastroenterol 1991; 23 (Supl 2): 105.
13. Bell GD, Powell KU, Weil J, Burridge SM, Morden A, Harrison G et al. Experience with omeprazole in combination with either amoxycillin or colloidal bismuth subcitrate in patients with metronidazole-resistant Helicobacter pylori. Eur J Gastroenterol Hepatol 1991; 3: 923-926.
14. Logan RPH, Rubio MA, Gummert PA, Hegarty B, Walker MM, Baron JH et al. Omeprazole and amoxycillin suspension for Helicobacter pylori. Isr J Med Sci 1992; 161 (Supl 10): 16.
15. Lamouliatte H, Cayla R, Zerbib F, Mégraud F. Dual therapy versus triple therapy for Helicobacter pylori eradication. Preliminary results of a randomized controlled trial [resumen]. Gastroenterology 1993; 106: 120.
16. Cayla R, Werbib F, Mascarel A, Mégraud F, Lamouliatte H. Dual therapy with high dose of omeprazole versus triple therapy using omeprazole in combination with two antibiotics for Helicobacter pylori eradication: results of a randomized controlled trial among 100 patients. Am J Gastroenterol 1994; 89: 1.366.
17. Hardy DJ, Hanson CW, Hensey DM, Beyer JM, Fernandes PB. Susceptibility of Campylobacter pylori to macrolides and fluoroquinolones. J Antimicrob Chemother 1988; 22: 631-636.
18. Goldman RC, Zakula D, Flamm R, Beyer J, Capobianco J. Tigh binding of clarithromycin, its 14-(R)-hydroxy metabolite, and erythromycin to Helicobacter pylori ribosomes. Antimicrob Agents Chemother 1994; 38: 1.496-1.500.
19. Chang K, Wyle F, Skankey G, Kidao J, Remiggio D, Lai A et al. Clarithromycin achieves highest gastric mucosa tissue level among anti-Helicobacter pylori antibiotics [resumen]. Boston: Digestive Disease Week, mayo 1993; 2.399.
20. Peterson WL, Graham D, Marshall B, Blaser MJ, Genta RM, Klein PD et al. Clarithromycin as monotherapy for eradication of Helicobacter pylori: a randomized, double-blind trial. An J Gastroenterol 1993; 88: 1.860-1.864.
21. Cayla R, Zerbib F, Talbi P, Mégraud F, Lamouliatte H. Pre and post-treatment clarithromycin resistance of Helicobacter pylori strains: a key factor of treatment failure [resumen]. Gut 1995; 37 (Supl 1): 386.
22. Hardy DJ, Guay DRP, Jones RN. Clarithromycin, a unique macrolide: a pharmacokinetic, microbiological, and clinical overview. Diagn Microbiol Infect Dis 1992; 15: 39-53.
23. Graham DY, Operkun AR, Klein PD. Clarithromycin for the eradication of Helicobacter pylori. J Clin Gastroenterol 1993; 16: 292-294.
24. Logan RPH, Gummett PA, Hegarty BT, Walker MM, Baron JH, Misiewicz JJ. Clarithromycin and omeprazole for Helicobacter pylori. Lancet 1992; 340: 239.
25. Lind T, Veldhuyzen SJO, Unge P, Spiller RC, Bayerdörffer E, O'Morain C et al. The MACH 1 study: optimal one-week treatment for Helicobacter pylori defined? [resumen]. Gut 1995; 37 (Supl 2): 186.
26. Labenz J, Adamek RJ, Tillenburg B, Peitz U, Becker T, Stolte M et al. One-week treatment with omeprazole, amoxicillin and clarithromycin or metronidazole for cure of Helicobacter pylori infection [resumen]. Gut 1995; 37 (Supl 1): 172.
27. Burette A, Glupczynski Y, Deprez C, Ramdani B. Omeprazole + amoxicillin + clarithromycin therapy for Helicobacter pylori infection [resumen]. Gut 1995; 37 (Supl 1): 353.
28. Reilly TG, Poxon V, Walt RP. The eradication of Helicobacter pylori in practice: an audit of three clinical experience with peptic ulcer patients [resumen]. Gut 1995; 37 (Supl 1): 345.
29. Goddard AF, Logan RPH, Tonge KA, Gummett PA, Hawkey CJ, Misiewicz JJ et al. Eradication of Helicobacter pylori using clarithromycin, omeprazole and amoxycillin for one week [resumen]. Gut 1995; 37 (Supl 1): 350.
30. Trespi E, Villani L, Broglia F, Luinetti O, Colla C, Fiocca R et al. High efficacy of a clarithromycin-amoxycillin-omeprazole association for Helicobacter pylori eradication and treatment of ulcerlike or reflux-like dyspeptic symptoms [resumen]. Gut 1995; 37 (Supl 1): 346.
31. Delchier JC, Elamine I, Goldfain D, Chaussade S, Mancini L, Idström JP. Comparison of omeprazole (OM) + amoxicillin (AM) versus OM + clarithromycin (CLA) in the eradication of Helicobacter pylori. Results from a randomized study involving 120 patients [resumen]. Gut 1995; 37 (Supl 1): 219.
32. GASUD (Abruzzo Group for the Study of Duodenal Ulcer), Ferrini G, De Fanis C, Della Sciucca A, Falcucci M, Grossi L et al. Effect of omeprazole, clarithromycin and amoxicillin for a short time on Helicobacter pylori eradication [resumen]. Gut 1995; 37 (Supl 2): 247.
33. Hirschowitz BI, Mohnen J, Shaw S. Omeprazole with amoxicillin alone or with clarithromycin to treat Helicobacter pylori [resumen]. Gastroenterology 1995; 108: 115.
34. Moayyedy P, Tompkins DS, Axon ATR. Efficacy of ten days of clarithromycin, amoxycillin and omeprazole in eradicating Helicobacter pylori infection [resumen]. Gut 1995; 37 (Supl 1): 176.
35. Blanco M, Pajares JM, Moreno MJ. Is gastric metaplasia a factor in relapsing duodenal ulcer? Rev Esp Enf Digest 1990; 78 (Supl): 72-75.
36. Katelaris PH, Seow F, Lin BPC, Napoli J, Ngu MC, Jones DB. Effect of age, Helicobacter pylori infection, and gastritis with atrophy on serum gastrin and gastric acid secretion in healthy men. Gut 1993; 34: 1.032-1.036.
37. McNulty CAM. Bacteriological and pharmacological basis for the treatment of Campylobacter pylori infection. En: Rathbone BJ, Heatley RV, editores. Campylobacter pylori and gastroduodenal disease. Oxford: Blackwell Scientific Publications, 1989; 209-216.
38. Robert ME, Weinstein WM. Helicobacter pyloriassociated gastric pathology. En: Dooley CP, Cohen H, editores. Helicobacter pylori infection. Filadelfia: W.P. Saunders, 1993; 22: 59-72.
39. Labenz J, Leverkus F, Börsch G. Omeprazole plus amoxicillin for cure of Helicobacter pylori infection. Factors influencing the treatment success. Scand J Gastroenterol 1994; 29: 1.070-1.075.
40. Graham DY, Lew GM, Maluty HM, Evans DG, Wvans DJ Jr, Klein PD et al. Factors influencing the eradication of Helicobacter pylori with triple therapy. Gastroenterology 1992; 102: 493-496.
41. Cutler AF, Schubert TT. Patient factors affecting Helicobacter pylori eradication with triple therapy. Am J Gastroenterol 1993; 88: 505-509.
42. De Bartolo M, Reitmayer R, Olson C, Edmonds A. Effect of smoking on Helicobacter pylori eradication and duodenal ulcer recurrence in patients receiving dual therapy with clarithromycin in combination with omeprazole [resumen]. Gut 1995; 37 (Supl 2): 81.
43. Bazzoli F, Zagari RM, Fossi S, Pozzato P, Alampi G, Simoni P et al. Short-term low-dose triple therapy for the- eradication of Helicobacter pylori. Eur J Gastroenterol 1994; 6: 773-777.
44. Yousfin MM, El-Zimaity HMT, Al-Assi MT, Cole RA, Genta RM, Graham DY. Metronidazole, omeprazole, and clarithromycin: an effective combination therapy for Heticobacter pylori infection [resumen]. Gastroenterology 1995; 108: 265.
45. Forné M, Viver JM, Espinós JC, Coll I, Tresserra F, Garau J. Impact of colloidal bismuth subcitrate in the eradication rates of Helicobacter pylori infection-associated duodenal ulcer using a short treatment regimen with omeprazole and clarithromycin: a randomized study. Am J Gastroenterol 1995; 90: 718-721.
46. Jaup BH, Norrby A. Low dose short term triple therapy for eradication of Helicobacter pylori [resumen]. Am J Gastroenterol 1994; 89: 1.400.
47. Hosking SW, Ling TKW, Ching SCS, Yung MY, Cheng AF, Sung JJ et al. Duodenal ulcer healing by eradication of Helicobacter pylori without anti-acid treatment: randomised controlled trial. Lancet 1994; 343: 508-510.
48. Gisbert JP, Boixeda D, Mur Villacampa M, Monés J, Sáinz Samitier R, Martin de Argila C. Response to article by Dr. Forné et al. Am J Gastroenterol 1996; 91: 176-177.
49. Graham DY, Lew GM, Evans DG, Evans DJ Jr, Klein PK. Effect of triple therapy (antibiotics plus bismuth) on duodenal ulcer healing with ranitidine. Ann Intern Med 1991; 115: 266-269.
50. O'Connor HJ, Kanduru C, Bhutta AS, Meehan JM, Feeley KM, Cunnane K. Effect of Helicobacter pylori eradication on peptic ulcer healing. Postgrad Med J 1995; 71: 90-93.
51. Gisbert JP, Boixeda D, De Rafael L, Álvarez Baleriola I, Martin de Argila C, García M et al. ¿De qué factures depende la cicatrización ulcerosa duodenal cuando empleamos un tratamiento erradicador de Helicobacter pylori? Rev Esp Enf Digest 1996; 88: 179-184.
52. Sung JJY, Chung SCS, Ling TKW, Yung MY, Leung VK, Ng EK et al. Antibacterial treatment of gastric ulcers associated with Helicobacter pylori. N Engl J Med 1995; 332: 139-142.
53. Gisbert JP, Boixeda D, Álvarez Baleriola I, Redondo C, De Rafael L, Martín de Argila C et al. Evolución de las lesiones histológicas de la mucosa géstrica tras la erradicación de Helicobacter pylori en pacientes con úlcera duodenal. Estudio inicial y a los 6 meses. Rev Esp Enf Digest 1995; 87: 281-287.
54. Gisbert JP, Boixeda D, Vila T, De Rafael L, Redondo C, Martín de Argila C. Basal and stimulated gastrin levels and gastric acid output five months after therapy for Helicobacter pylori eradication in duodenal ulcer patients. J Clin Gastroenterol 1996; 22: 90-95.
55. Dobrilla G, De Pretis G, Amplatz S, Benvenuti S, De Guelmi A. Endogenous and exogenous factors influencing ulcer relapse, resistance to treatment and complications. Gastroenterol Int 1994; 7: 156-171.
56. Moshal MG, Spitaels JM, Khan F, Mason S, Naidoo J, Schlemmer L. Factors affecting duodenal ulcer healing. Four double-blind trials in 193 patients. South Afr Med J 1982; 61: 202-206.
57. Adami HO, Bjoerklund O, Enander LK, Gustavsson S, Loeoef L, Nordahl A. Cimetidine or propantheline combined with antacid therapy for short-term treatment of duodenal ulcer. Dig Dis Sci 1982; 17: 953-959.
58. Berstad A, Rydning A, Aadland E, Kolstad B, Frislid K, Aaseth J. Controlled clinical trial of duodenal ulcer healing with antacid tablets. Scand J Gastroenterol 1982; 17: 953-959.
59. Jaup BH, Norrby A. Low dose, short-term triple therapy for cure of Helicobacter pylori infection and healing of peptic ulcers. Am J Gastroenterol 1995; 90: 943-945.
60. Moayyedi P, Sahay P, Tompkins DS, Axon ATR. Efficacy and optimum dose of omeprazole in a new 1-week triple therapy regimen to eradicate Helicobacter pylori. Eur J Gastroenterol Hepatol 1995; 7: 835-840.
61. Powell KU, Bell GD, Bowden AF, Trowell JE, Jones PH. An effective one-week Helicobacter pylori eradication therapy using omeprazole, clarithromycin and metronidazole. Br J Clin Res 1995; 6: 85-90.
62. Bell GD,Powell DU, Burridge SM, Bowden AF, Atoyebi W, Bolton GH et al. Rapid eradication of Helicobacter pylori infection. Aliment Pharmacol Ther 1995; 9: 41-46.