Efflux of γ-aminobutyric acid caused by changes in ion concentrations and cell swelling simulating the effect of cerebral ischaemia

Acta Neurochirurgica

Volumn 139, Issue 5, 1997, Pages 453-463

  Haugstad, T S ^a,b,c   Karlsen, H E ^b   Krajtci P ^b   Due Tonnessen B ^b   Larsen, M ^a,b   Sandberg, C ^a,b   Sand, O ^b   Brandtzaeg, P ^b   Langmoen, I A ^a,b  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Brain slice; Cerebral ischaemia; GABA release; GAT 1

Indexed keywords

4 AMINOBUTYRIC ACID; CHLORIDE ION; CHOLINE; ISETHIONIC ACID; MANNITOL; POTASSIUM ION; SODIUM CHLORIDE; SODIUM ION; TETRODOTOXIN;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN SLICE; CELL MEMBRANE DEPOLARIZATION; CELL SWELLING; MALE; NONHUMAN; OOCYTE; OSMOLARITY; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; RAT; SODIUM CELL LEVEL; XENOPUS;

ANIMALS; BRAIN EDEMA; BRAIN ISCHEMIA; CARRIER PROTEINS; CELL SURVIVAL; CULTURE TECHNIQUES; ELECTROLYTES; ENERGY METABOLISM; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION; HIPPOCAMPUS; MALE; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; OOCYTES; ORGANIC ANION TRANSPORTERS; RATS; RATS, WISTAR; XENOPUS;

EID: 0030904743     PISSN: 00016268     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01808883     Document Type: Article

References (68)

1. Andersen P, Silfvenius H, Sundberg SH, Sveen O, Wigström H (1978) Functional characteristics of unmyelinated fibres in the hippocampal cortex. Brain Res 144: 11-18
2. Attwell D, Barbour B, Szatkowski M (1993) Nonvesicular release of neurotransmitter. Neuron 11: 401-407
3. Attwell D, Sarantis M, Barbour B, Brew H (1989) Electrogenic glutamate uptake in amphibian and mammalian retinal glial cells. Acta Physiol Scand 136 [Suppl 582]: 44
4. Barbour B, Brew H, Attwell D (1988) Electrogenic glutamate uptake in glial cells is activated by intracellular potassium. Nature 335: 433-435
5. Bedard E, Morris CE (1992) Channels activated by stretch in neurons of a helix snail. Can J Physiol Pharmacol 70: 207-213
6. Berg-Johnsen J, Grøndahl TØ, Langmoen IA, Haugstad TS, Hegstad E (1995) Changes in amino acid release and membrane potential during cerebral hypoxia and glucose deprivation. Neurol Res 17: 201-208
7. Bernath S (1992) Calcium-independent release of amino acid neurotransmitters: fact or artifact? Progr Neurobiol 38: 57-91
8. Billups B, Attwell D (1996) Modulation of non-vesicular glutamate release by pH. Nature 379: 171-174
9. B receptor subtypes. Trends Neurosci 11: 112-116
10. Bouvier M, Szatkowski M, Amato A, Attwell D (1992) The glial cell glutamate uptake carrier countertransports pH-changing anions. Nature 360: 471-474
11. Brew H, Attwell D (1987) Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells. Nature 327: 707-709
12. Burke SP, Taylor CP (1992) Hippocampal glutamate release during "in vitro ischemia" is calcium-independent and TTX-sensitive. Soc Neurosci Abstr 17: 1267
13. Cammack JN, Rakhilin SV, Schwartz EA (1994) A GABA transporter operates asymmetrically and with variable stochiometry. Neuron 13: 949-960
14. Casado M, Bendahan A, Zafra F, Danbolt NC, Aragón C, Giménez C, Kanner BI (1993) Phosphorylation and modulation of brain glutamate transporters by protein kinase C. J Biol Chem 268: 27313-27317
15. Casado M, Zafra F, Aragón C, Giménez C (1991) Activation of high-affinity uptake of glutamate by phorbol esters in primary glial cell cultures. J Neurochem 57: 1185-1190
16. Catterall WA (1980) Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes. Ann Rev Parmacol Toxicol 20: 15-43
17. + currents in squid axon. Cell Mol Neurobiol 5: 311-320
18. Erecinska M (1987) The neurotransmitter amino acid transport systems. A fresh outlook on an old problem. Biochem Pharmacol 36: 3547-3555
19. Fairman WA, Vandenberg RJ, Arizza JL, Kavanaugh MP, Amara SG (1995) An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 375: 599-603
20. Godel H, Graser T, Földi P, Pfaender P, Fürst P (1984) Measurement of free amino acids in human biological fluids by high-performance liquid chromatography. J Chromatogr 297: 49-61
21. Grøndahl TØ, Langmoen IA (1993) Possible involvement of chloride ions in cerebral ischemic injury. J Cereb Blood Flow Metab 13: S88
22. Guastella J, Brecha N, Weigmann C, Lester HA, Davidson N (1992) Cloning, expression and localization of a rat brain high-affinity glycine transporter. Proc Natl Acad Sci USA 89: 7189-7193
23. Guastella J, Nelson N, Nelson H, Czyzyk L, Keynan S, Miedel MC, Davidson N, Lester HA, Kanner BI (1990) Cloning and expression of a rat brain GABA transporter. Science 249: 1303-1306
24. Guhary F, Sachs F (1984) Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle. J Physiol 352: 685-701
25. Hansen AJ (1985) Effect of anoxia on ion distribution in the brain. Physiol Rev 65: 101-148
26. Hansen AJ, Zeuthen T (1981) Extracellular ion concentrations during spreading depression and ischemia in the rat brain cortex. Acta Physiol Scand 113: 437-445
27. Haugstad TS, Hegstad E, Langmoen IA (1992) Calcium dependent release of γ-aminobutyric acid (GABA) from human cerebral cortex. Neurosci Lett 141: 61-64
28. Haugstad TS, Langmoen IA (1996) Release of brain amino acids during hyposmolar stress and energy deprivation. J Neurosurg Anesth 8: 159-168
29. Haugstad TS, Valø ET, Langmoen IA (1995) Changes in brain amino acid content induced by hyposmolar stress and energy deprivation. Neurol Res 17: 402-408
30. Hegstad E, Berg-Johnsen J, Haugstad TS, Hauglie-Hanssen E, Langmoen IA (1996) Amino-acid release from human cerebral cortex during simulated ischaemia in vitro. Acta Neurochir (Wien) 138: 234-241
31. Hille B (1992) Ionic channels of excitable membranes, 2nd Ed. Simmer, Sunderland, MA
32. Ikeda M, Nakazawa T, Abe K, Kaneko T, Yamatsu K (1989) Extracellular accumulation of glutamate in the hippocampus induced by ischemia is not calcium dependent - in vitro and in vivo evidence. Neurosci Lett 96: 202-206
33. Islas L, Pasantes-Morales H, Sanchez JA (1993) Characterization of stretch-activated ion channels in cultured astrocytes. Glia 8: 87-96
34. Kanai Y, Hediger MA (1992) Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360: 467-471
35. Katayama Y, Kawamata T, Tamura T, Hovda DA, Becker DP, Tsubokawa T (1991) Calcium-dependent glutamate release concomitant with massive potassium flux during cerebral ischemia in vivo. Brain Res 558: 136-140
36. Katz B, Miledi R (1967) The timing of calcium action during neuromuscular transmission. J Physiol 189: 535-544
37. Kimelberg HK, Rose JW, Barron KD, Waniewski RA, Cragoe EJ (1989) Astrocytic swelling in traumatic-hypoxic brain injury. Mol Chem Neuropath 11: 1-31
38. Korf J, Klein HC, Venema K, Postema F (1988) Increase in striatal and hippocampal impedance and extracellular levels of amino acids by cardiac arrest in freely moving rats. J Neurochem 50: 1087-1095
39. Langmoen IA, Andersen P (1981) The hippocampal slice in vitro. A description of the technique and some examples of the opportunities it offers. In: Kerkut GA, Wheal H (eds) Electrophysiology of isolated mammalian CNS preparations. Academic Press, London, pp 51-105
40. Levi G, Raiteri M (1993) Carrier-mediate release of neurotransmitters. Trends Neurosci 16: 415-419
41. Lindroth P, Mopper K (1979) High performance liquid chromatographic determination of subpicomole amounts of amino acids by precolumn fluorescence derivatization with o-phthaldialdehyde. Anal Chem 51: 1667-1674
42. Lui Q-R, Lópex-Corcuera B, Mandiyan S, Nelson H, Nelson N (1993) Molecular characterization of four pharmacologically distinct γ-aminobutyric acid transporters in mouse brain. J Biol Chem 268: 2106-2112
43. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275
44. Mager S, Naeve J, Quick M, Labarca C, Davidson N, Lester H (1993) Steady states, charge movements and rates tor a cloned GABA transporter expressed in Xenopus oocytes. Neuron 10: 177-188
45. Martinac B, Buechner M, Delcour AH, Adler J, Kung C (1987) Pressure-sensitive ion channel in Escherichia coli. Proc Natl Acad Sci USA 84: 2297
46. Nicholls D, Attwell D (1990) The release and uptake of excitatory amino acids. Trends Pharmacol Sci 11: 462-468
47. Osikowska-Evers BA, Wilhelm D, Nebel U, Hennemann P, Scheufler E, Tegtmeier F (1995) The effects of the novel neuroprotective compound lubeluzole on sodium current and veratridine induced sodium load in rat brain neurons and synaptososmes. J Cereb Blood Flow Metab 15: S380
48. Piccolino M, Pignatelli A (1996) Calcium-independent synaptic transmission: artifact or fact. Trends Neurosci 19: 120-125
49. Pines G, Danbolt NC, Bjørås M, Zhang Y, Bendahan A, Eide L, Koepsell H, Storm-Mathisen J, Seeberg E, Kanner BI (1992) Cloning and expression of a rat brain L-glutamate transporter. Nature 360: 464-467
50. Rothman SM (1985) The neurotoxicity of excitatory amino acids is produced by passive chloride influx. J Neurosci 5: 1483-1489
51. Sanchez-Olea R, Morán J, Schousboe A, Pasantes-Morales H (1991) Hyposmolarity-activated fluxes of taurine in astrocytes are mediated by diffusion. Neurosci Lett 130: 2336
52. Scheller D, Kolb J, Szathmary S, Zacharias E, de Ryck M, Reempts Jv, Clincke G, Tegtmeier F (1995) Extracellular changes of glutamate in the periinfarct zone. Effect of lubeluzole. J Cereb Blood Flow Metab 15: S379
53. Siesjö BK (1992) Pathophysiology and treatment of focal cerebral ischemia - part I: pathophysiology. J Neurosurg 77: 169-184
54. Snutch TP (1988) The use of Xenopus oocytes to probe synaptic communication. Trends Neurosci 11: 250-256
55. Solis JM, Herranz AS, Herreras O, Lerma J, del Rio RM (1988) Does taurine act as an osmoregulatory substance in the rat brain? Neurosci Lett 91: 53-58
56. +-ATPase activity. J Neurosci 14: 2464-2475
57. Sontheimer H, Waxman S (1993) Expression of voltage-activated ion channels by astrocytes and oligodendrocytes in the hippocampal slice. J Neurophysiol 70: 1863-1873
58. +-dependent glutamate/aspartate transporter from rat brain. Proc Natl Acad Sci USA 89: 10955-10959
59. Sukharev SI, Blount P, Martinac B, Blattner FR, Kung C (1994) A large-conductance mechanosensitive channel in E. coli encoded by mscL alone. Nature 368: 265-268
60. Szatkowski M, Barbour B, Attwell D (1990) Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake. Nature 348: 443-446
61. + currents that fail to inactivate. Trends Neurol Sci 16: 455-460
62. Taylor CP, Weber M (1992) Effect of sodium channel modulating drugs on loss of EPSPs from hypoxial/hypoglycemia in rat hippocampal slices in vitro. Soc Neurosci Abstr 18: 1135
63. Thoroed SM (1992) Taurine transport and volume regulation of flounder erythrocytes under hyposmotic conditions. PhD Thesis, University of Oslo, Department of Biology, Division of General Physiology
64. Trotti D, Rossi D, Gjesdal O, Levy LM, Racagni G, Danbolt NC, Volterra A (1996) Peroxynitrite inhibits glutamate transporter subtypes. J Biol Chem 271: 5976-5979
65. Uhl GR (1992) Neurotransmitter transporters (plus): a promising new gene family. Trends Neurosci 15: 265-268
66. Wahizu Y (1971) Some effects of clonidine, procaine and tetrodotoxin on crayfish sensory neuron. Eur J Pharmacol 14: 384-388
67. Yancey PH, Clark ME, Hand SC, Bowlus RD, Somero GN (1982) Living with water stress: evolution of osmolyte systems. Science 217: 1214-1222
68. Aas J-E, Berg-Johnsen J, Hegstad E, Laake JH, Langmoen IA, Ottersen OP (1993) Redistribution of glutamate and glutamine in slices of human neocortex exposed to combined hypoxia and glucose deprivation in vitro. J Cereb Blood Flow Metab 13: 503-515