Thiazolyl and benzothiazolyl hydrazones derived from α-(N)-acetylpyridines and diazines: Synthesis, antiproliferative activity and CoMFA studies

European Journal of Medicinal Chemistry

Volumn 32, Issue 5, 1997, Pages 397-408

  Easmon, J ^a   Heinisch, G ^a   Hofmann, J ^a   Langer, T ^a   Grunicke, H H ^a   Fink, J ^a   Purstinger G ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Antiproliferative agent; CoMFA; Hydroxyurea resistant tumor; Thiazolyl and benzothiazolyl hydrazone; )(N) acetylheteroarene derivative

Indexed keywords

BENZOTHIAZOLE DERIVATIVE; HYDRAZONE DERIVATIVE; HYDROXYUREA;

ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; BURKITT LYMPHOMA; CANCER; COLON ADENOCARCINOMA; CYTOSTASIS; DRUG ACTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN TISSUE; LEUKEMIA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STEREOCHEMISTRY; UTERINE CERVIX CARCINOMA;

EID: 0030904659     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(97)81677-7     Document Type: Article

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