-
1
-
-
0024398920
-
Cyclooxygenase inhibition unmasks the full antidiuretic activity of the vasopressin antagonist, SK&F 101926, in dogs
-
ALBRIGHTSON-WINSLOW, C. R., CALDWELL, N., BROOKS, D. P., HUFFMAN, W., STASSEN, F. L. AND KINTER, L. B.: Cyclooxygenase inhibition unmasks the full antidiuretic activity of the vasopressin antagonist, SK&F 101926, in dogs. J. Pharmacol. Exp. Ther. 249: 66-371, 1989.
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.249
, pp. 66-371
-
-
Albrightson-Winslow, C.R.1
Caldwell, N.2
Brooks, D.P.3
Huffman, W.4
Stassen, F.L.5
Kinter, L.B.6
-
2
-
-
0002467047
-
Species heterogeneity and antidiuretic hormone antagonists: What are the predictors?
-
ed. BY A. W. Cowley, J. F. Liard and D. Aussiello, Raven Press, New York
-
ALLISON, N., ALBRIGHTSON-WINSLOW, C. R., BROOKS, D. P., STASSEN, F. L., HUFFMAN, W. F., STOTE, R. M. AND KINTER, L. B.: Species heterogeneity and antidiuretic hormone antagonists: what are the predictors? In Vasopressin, Cellular and Integrative Functions, ed. BY A. W. Cowley, J. F. Liard and D. Aussiello, pp. 207-214, Raven Press, New York, 1988.
-
(1988)
Vasopressin, Cellular and Integrative Functions
, pp. 207-214
-
-
Allison, N.1
Albrightson-Winslow, C.R.2
Brooks, D.P.3
Stassen, F.L.4
Huffman, W.F.5
Stote, R.M.6
Kinter, L.B.7
-
3
-
-
0029024371
-
Aquaretic effect of the kappa opioid agonist RU 51599 in cirrhotic rats with ascites and water retention
-
BOSCH-MARCE, M., JIMENEZ, W., ANGELI, P., LEIVAS, A., CLARIA, J., GRAZIOTTO, A., ARROYO, V., RIVERA, F. AND RODES, J.: Aquaretic effect of the kappa opioid agonist RU 51599 in cirrhotic rats with ascites and water retention. Gastroenterology 109: 217-223, 1995.
-
(1995)
Gastroenterology
, vol.109
, pp. 217-223
-
-
Bosch-Marce, M.1
Jimenez, W.2
Angeli, P.3
Leivas, A.4
Claria, J.5
Graziotto, A.6
Arroyo, V.7
Rivera, F.8
Rodes, J.9
-
4
-
-
0030452022
-
Development of selective water diuretics: Potential molecular targets
-
BROOKS, D. P.: Development of selective water diuretics: Potential molecular targets. Pharmacol. Commun. 8: 75-80, 1996.
-
(1996)
Pharmacol. Commun.
, vol.8
, pp. 75-80
-
-
Brooks, D.P.1
-
6
-
-
0027361339
-
Opiate receptors within the blood-brain barrier mediate kappa agonist-induced water diuresis
-
BROOKS, D. P., GIARDINA, G., GELLAI, M., DONDIO, G., EDWARDS, R. M., PETRONE, G. P., DEPALMA, P. D., SBACCHI, M., JUGUS, M., MISIANO, P., WANG, Y-X. AND CLARKE, G. D.: Opiate receptors within the blood-brain barrier mediate kappa agonist-induced water diuresis. J. Pharmacol. Exp. Ther. 266: 164-171, 1993.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.266
, pp. 164-171
-
-
Brooks, D.P.1
Giardina, G.2
Gellai, M.3
Dondio, G.4
Edwards, R.M.5
Petrone, G.P.6
Depalma, P.D.7
Sbacchi, M.8
Jugus, M.9
Misiano, P.10
Wang, Y.-X.11
Clarke, G.D.12
-
7
-
-
0023920843
-
SK&F 105494 is a potent vasopressin antidiuretic antagonist in the rhesus monkey (Macaca mulatta)
-
BROOKS, D. P., KOSTER, P. F., ALBRIGHTSON-WINSLOW, C. R., STASSEN, F. L., HUFFMAN, W. AND KINTER, L. B.: SK&F 105494 is a potent vasopressin antidiuretic antagonist in the rhesus monkey (Macaca mulatta). J. Pharmacol. Exp. Ther. 245: 211-215, 1988.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.245
, pp. 211-215
-
-
Brooks, D.P.1
Koster, P.F.2
Albrightson-Winslow, C.R.3
Stassen, F.L.4
Huffman, W.5
Kinter, L.B.6
-
8
-
-
0024271374
-
SK&F 105494: A potent antidiuretic hormone antagonist devoid of partial agonist activity in dogs
-
CALDWELL, N., BRICKSON, B., KINTER, L. B., BROOKS, D. P., HUFFMAN, W. F., STASSEN, F. L. AND ALBRIGHTSON-WINSLOW, C.: SK&F 105494: A potent antidiuretic hormone antagonist devoid of partial agonist activity in dogs. J. Pharmacol. Exp. Ther. 247: 897-901, 1988.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.247
, pp. 897-901
-
-
Caldwell, N.1
Brickson, B.2
Kinter, L.B.3
Brooks, D.P.4
Huffman, W.F.5
Stassen, F.L.6
Albrightson-Winslow, C.7
-
10
-
-
0000500069
-
Evaluation of a kappa opioid agonist, spiradolone, in comparison to morphine and placebo in the oral surgery model
-
DIONNE, R. A., DOBBINS, K. R. AND HARGREAVES, K. M.: Evaluation of a kappa opioid agonist, spiradolone, in comparison to morphine and placebo in the oral surgery model. Clin. Pharmacol. Ther. 49: 183, 1991.
-
(1991)
Clin. Pharmacol. Ther.
, vol.49
, pp. 183
-
-
Dionne, R.A.1
Dobbins, K.R.2
Hargreaves, K.M.3
-
11
-
-
0020620592
-
Determination of receptors that mediate opioid side effects in the mouse
-
HAYES, A. G. AND TYERS, M. B.: Determination of receptors that mediate opioid side effects in the mouse. Br. J. Pharmacol. 79: 731-736, 1983.
-
(1983)
Br. J. Pharmacol.
, vol.79
, pp. 731-736
-
-
Hayes, A.G.1
Tyers, M.B.2
-
12
-
-
2842526661
-
SK&F 105494 is antidiuretic in man
-
ILSON, B. E., JORKASKY, D. K., ALDINS, Z. AND STOTE, R. M.: SK&F 105494 is antidiuretic in man. Kidney Int. 37: 583, 1990.
-
(1990)
Kidney Int.
, vol.37
, pp. 583
-
-
Ilson, B.E.1
Jorkasky, D.K.2
Aldins, Z.3
Stote, R.M.4
-
13
-
-
0019523684
-
Locomotor activity and antinociception after putative mu, kappa and sigma opioid receptor agonists in the rat: Influence of dopaminergic agonists and antagonists
-
IWAMOTO, E. T.: Locomotor activity and antinociception after putative mu, kappa and sigma opioid receptor agonists in the rat: influence of dopaminergic agonists and antagonists. J. Pharmacol. Exp. Ther. 217: 451-460, 1981.
-
(1981)
J. Pharmacol. Exp. Ther.
, vol.217
, pp. 451-460
-
-
Iwamoto, E.T.1
-
14
-
-
0020693721
-
A kappa opioid effect: Increased urination in the rat
-
LEANDER, J. D.: A kappa opioid effect: increased urination in the rat. J Pharmacol. Exp. Ther. 224: 89-94, 1983.
-
(1983)
J Pharmacol. Exp. Ther.
, vol.224
, pp. 89-94
-
-
Leander, J.D.1
-
15
-
-
0027496672
-
Central kappa opioid receptor-evoked changes in renal function in conscious rats: Participation of renal nerves
-
KAPUSTA, D. R. AND OBIH, J. C.: Central kappa opioid receptor-evoked changes in renal function in conscious rats: participation of renal nerves. J. Pharmacol. Exp. Ther. 267: 197-204, 1993.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.267
, pp. 197-204
-
-
Kapusta, D.R.1
Obih, J.C.2
-
16
-
-
0023352125
-
Characterization and mechanism of action of vasopressin antagonists in squirrel monkeys (Saimiri sciureus)
-
KINTER, L. B., CHURCHILL, S., STASSEN, F. L., MOORE, M. AND HUFFMAN, W.: Characterization and mechanism of action of vasopressin antagonists in squirrel monkeys (Saimiri sciureus). J. Pharmacol. Exp. Ther. 241: 797-803, 1987.
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.241
, pp. 797-803
-
-
Kinter, L.B.1
Churchill, S.2
Stassen, F.L.3
Moore, M.4
Huffman, W.5
-
17
-
-
0019509818
-
Characterization of the kappa subtype of the opioid receptor in the guinea pig brain
-
KOSTERLITZ, H. W. PATERSON, S. J. AND ROBSON, L. E.: Characterization of the kappa subtype of the opioid receptor in the guinea pig brain. Br. J. Pharmacol. 73: 939-949, 1981.
-
(1981)
Br. J. Pharmacol.
, vol.73
, pp. 939-949
-
-
Kosterlitz, H.W.1
Paterson, S.J.2
Robson, L.E.3
-
18
-
-
0019830566
-
Synthetic antagonists of in vivo antidiuretic and vasopressor responses to arginine vasopressin
-
MANNING, M., LAMMEK, B., KOLODZIEJCZYK, A. M., SETO, J. AND SAWYER, W.: Synthetic antagonists of in vivo antidiuretic and vasopressor responses to arginine vasopressin. J. Med. Chem. 24: 701-706, 1981.
-
(1981)
J. Med. Chem.
, vol.24
, pp. 701-706
-
-
Manning, M.1
Lammek, B.2
Kolodziejczyk, A.M.3
Seto, J.4
Sawyer, W.5
-
19
-
-
0019061918
-
Ligand, a versatile computerized approach for characterization of ligand-binding systems
-
MUNSON, P. J. AND RODBARD, D.: Ligand, a versatile computerized approach for characterization of ligand-binding systems. Anal. Biochem. 107: 220-239, 1980.
-
(1980)
Anal. Biochem.
, vol.107
, pp. 220-239
-
-
Munson, P.J.1
Rodbard, D.2
-
20
-
-
0027143189
-
A novel nonpeptide selective vasopressin 2 antagonist (OPC-31260) in men
-
OHNISHI, A., ORITA, Y., OKAHARA, R., FUJIHARA, H., INOUE, T., YAMAMURA, Y., YABUUCHI, Y. AND TANAKA, T.: A novel nonpeptide selective vasopressin 2 antagonist (OPC-31260) in men. J. Clin. Invest, 92: 2653-2659, 1993.
-
(1993)
J. Clin. Invest
, vol.92
, pp. 2653-2659
-
-
Ohnishi, A.1
Orita, Y.2
Okahara, R.3
Fujihara, H.4
Inoue, T.5
Yamamura, Y.6
Yabuuchi, Y.7
Tanaka, T.8
-
21
-
-
0028309021
-
Aquaretic effect of the stable dynorphin-A analog E2078 in the human
-
OHNISHI, A., MIHARA, M., YASUDA, S., TOMONO, Y., HASEGAWA, J. AND TANAKA, T.: Aquaretic effect of the stable dynorphin-A analog E2078 in the human. J. Pharmacol. Exp. Ther. 270: 42-347, 1994.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 42-347
-
-
Ohnishi, A.1
Mihara, M.2
Yasuda, S.3
Tomono, Y.4
Hasegawa, J.5
Tanaka, T.6
-
22
-
-
0000039922
-
Human central nervous system (CNS) effects of a elective kappa opioid agonist
-
PETERS, G. AND GAYLOR, S.: Human central nervous system (CNS) effects of a elective kappa opioid agonist. Clin. Pharmacol. 45: 130, 1989.
-
(1989)
Clin. Pharmacol.
, vol.45
, pp. 130
-
-
Peters, G.1
Gaylor, S.2
-
23
-
-
0024348076
-
Regional variations in binding capacities at mu, delta and kappa opioid sites in membrane suspensions from rabbit brain
-
PETRILLO, P., LA REGINA, A., SBACCHI, M., TAVANI, T., ROBSON, L. E. AND KOSTERLITZ, H. W.: Regional variations in binding capacities at mu, delta and kappa opioid sites in membrane suspensions from rabbit brain. Eur. J. Pharmacol. 166: 213-217, 1989.
-
(1989)
Eur. J. Pharmacol.
, vol.166
, pp. 213-217
-
-
Petrillo, P.1
La Regina, A.2
Sbacchi, M.3
Tavani, T.4
Robson, L.E.5
Kosterlitz, H.W.6
-
24
-
-
0028102960
-
Diuretic effects, pharmacokinetics and safety of a new centrally acting kappa opioid agonist (CI-977) in humans
-
REECE, P. A., SEDMAN, A. J., ROSE, S., WRIGHT, D. S., DAWKINS, R. AND RAJAGOPALAN, R.: Diuretic effects, pharmacokinetics and safety of a new centrally acting kappa opioid agonist (CI-977) in humans. J. Clin. Pharmacol. 34: 1126-1132, 1994.
-
(1994)
J. Clin. Pharmacol.
, vol.34
, pp. 1126-1132
-
-
Reece, P.A.1
Sedman, A.J.2
Rose, S.3
Wright, D.S.4
Dawkins, R.5
Rajagopalan, R.6
-
25
-
-
0026075799
-
Mechanism of diuretic action of spiradoline (U-62066E): A kappa opioid receptor agonist in the human
-
RIMOY, G. H., BHASKAR, N. K., WEIGHT, D. M. AND RUBIN, P. C.: Mechanism of diuretic action of spiradoline (U-62066E): A kappa opioid receptor agonist in the human. Br. J. Clin. Pharmacol. 32: 611-615, 1991.
-
(1991)
Br. J. Clin. Pharmacol.
, vol.32
, pp. 611-615
-
-
Rimoy, G.H.1
Bhaskar, N.K.2
Weight, D.M.3
Rubin, P.C.4
-
26
-
-
0029965289
-
Kappa opioid agonist inhibition of osmotically induced AVP release: Preferential action at hypothalamic sites
-
ROSSI, N. F. AND BROOKS, D. P.: Kappa opioid agonist inhibition of osmotically induced AVP release: preferential action at hypothalamic sites. Am. J. Physiol. 270: E367-E372, 1996.
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Rossi, N.F.1
Brooks, D.P.2
-
27
-
-
0025765298
-
From vasopressin antagonist to agonist: A saga of surprise!
-
RUFFOLO, R. R., JR., BROOKS, D. P., HUFFMAN, W. F. AND POSTE, G.: From vasopressin antagonist to agonist: A saga of surprise! Drug News Perspect. 4: 217-222, 1991.
-
(1991)
Drug News Perspect
, vol.4
, pp. 217-222
-
-
Ruffolo Jr., R.R.1
Brooks, D.P.2
Huffman, W.F.3
Poste, G.4
-
28
-
-
0019433197
-
Vasopressin analogs that antagonize antidiuretic responses by rats to the antidiuretic hormone
-
SAWYER, W. H., PANG, P. K. T., SETO, J., MCENROE, M., LAMMEK, B. AND MANNING, M.: Vasopressin analogs that antagonize antidiuretic responses by rats to the antidiuretic hormone. Science 212: 49-51, 1981.
-
(1981)
Science
, vol.212
, pp. 49-51
-
-
Sawyer, W.H.1
Pang, P.K.T.2
Seto, J.3
Mcenroe, M.4
Lammek, B.5
Manning, M.6
-
29
-
-
0025013313
-
BRL 52537: A novel, highly potent kappa opioid receptor ligand
-
SBACCHI, M. AND CLARKE, G. D.: BRL 52537: A novel, highly potent kappa opioid receptor ligand. In New Leads in Opioid Research, Excerpta Medica, International Congress Series, 914: 211-212, 1990.
-
(1990)
New Leads in Opioid Research, Excerpta Medica, International Congress Series
, vol.914
, pp. 211-212
-
-
Sbacchi, M.1
Clarke, G.D.2
-
30
-
-
0008936857
-
Aquaretic effect of Niravoline (RU 51599) a kappa opioid agonist in healthy volunteers
-
SINNASSAMY, P., SULTAN, E. AND BICHET, D. G.: Aquaretic effect of Niravoline (RU 51599) a kappa opioid agonist in healthy volunteers. J. Am. Soc. Nephrol. 5: 373, 1994.
-
(1994)
J. Am. Soc. Nephrol.
, vol.5
, pp. 373
-
-
Sinnassamy, P.1
Sultan, E.2
Bichet, D.G.3
-
31
-
-
0021892952
-
3H-EKC binding by opioids in rat kidney: A correlate to diuretic activity
-
3H-EKC binding by opioids in rat kidney: A correlate to diuretic activity. Life Sci. 36: 2189-2193, 1985.
-
(1985)
Life Sci.
, vol.36
, pp. 2189-2193
-
-
Slizgi, G.R.1
Ludens, J.H.2
-
32
-
-
0023059518
-
Role of ADH in ethylketocyclazocine-induced diuresis: Studies in the Brattleboro rat
-
SLIZGI, G. R. AND LUDENS, J. H.: Role of ADH in ethylketocyclazocine-induced diuresis: studies in the Brattleboro rat. Life Sci. 38: 2437-2440, 1986.
-
(1986)
Life Sci.
, vol.38
, pp. 2437-2440
-
-
Slizgi, G.R.1
Ludens, J.H.2
-
33
-
-
0020988809
-
Critical differences between species in the in vivo and in vitro responses to antidiuretic hormone antagonists
-
STASSEN, F. L., BRYAN, W., GROSS, M., KAVANAGH, B., SHUE, D., SULAT, L., WIEBELHAUS, V., YIM, N. AND KINTER, L. B.: Critical differences between species in the in vivo and in vitro responses to antidiuretic hormone antagonists. Prog. Brain Res. 60: 395-403, 1983.
-
(1983)
Prog. Brain Res.
, vol.60
, pp. 395-403
-
-
Stassen, F.L.1
Bryan, W.2
Gross, M.3
Kavanagh, B.4
Shue, D.5
Sulat, L.6
Wiebelhaus, V.7
Yim, N.8
Kinter, L.B.9
-
34
-
-
0025086815
-
Analgesic synergy and improved motor function produced by combinations of mu-delta and mu-kappa opioids
-
SUTTERS, K. A., MIASKOWSKI, C., TAIWO, Y. O. AND LEVINE, J. D.: Analgesic synergy and improved motor function produced by combinations of mu-delta and mu-kappa opioids. Brain Res. 530: 290-294, 1990.
-
(1990)
Brain Res.
, vol.530
, pp. 290-294
-
-
Sutters, K.A.1
Miaskowski, C.2
Taiwo, Y.O.3
Levine, J.D.4
-
35
-
-
0024849175
-
3H]-bremazocine in guinea pig brain: Evidence of multiplicity of the k-opioid receptors
-
3H]-bremazocine in guinea pig brain: Evidence of multiplicity of the k-opioid receptors. Can. J. Physiol. Pharmacol. 67: 1336-1344, 1988.
-
(1988)
Can. J. Physiol. Pharmacol.
, vol.67
, pp. 1336-1344
-
-
Tiberi, M.1
Magnan, J.2
-
36
-
-
15644365161
-
-
British Patent Applications no. 8926561.5 (Nov. 24, 1989) and no. 9003137.8 (Feb. 12, 1990). International Patent WO 91/08206 (June 13, 1991). U.S. Patent 5,322,848 (June 21, 1994)
-
VECCHIETTI, V., COLLE, R., GIARDINA, G., DONDIO, G. AND LEURINI, L.: N-Acylsubstituted azacyclic compounds, processes for their preparation and their use as pharmaceuticals. British Patent Applications no. 8926561.5 (Nov. 24, 1989) and no. 9003137.8 (Feb. 12, 1990). International Patent WO 91/08206 (June 13, 1991). U.S. Patent 5,322,848 (June 21, 1994).
-
N-Acylsubstituted Azacyclic Compounds, Processes for their Preparation and their use as Pharmaceuticals
-
-
Vecchietti, V.1
Colle, R.2
Giardina, G.3
Dondio, G.4
Leurini, L.5
-
37
-
-
0028239618
-
Contribution of alpha-2 adrenoceptors to kappa opioid agonist-induced water diuresis in the rat
-
WANG, Y-X., CLARKE, G. D., SBACCHI, M., PETRONE, G. AND BROOKS, D. P.: Contribution of alpha-2 adrenoceptors to kappa opioid agonist-induced water diuresis in the rat. J. Pharmacol. Exp. Ther. 270: 244-249, 1994.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 244-249
-
-
Wang, Y.-X.1
Clarke, G.D.2
Sbacchi, M.3
Petrone, G.4
Brooks, D.P.5
-
38
-
-
0024578653
-
Mechanism of diuretic action of U-62,066E, a kappa opioid receptor agonist
-
YAMADA, K., IMAI, M. AND YOSHIDA, S.: Mechanism of diuretic action of U-62,066E, a kappa opioid receptor agonist. Eur. J. Pharmacol. 160: 229-237, 1989.
-
(1989)
Eur. J. Pharmacol.
, vol.160
, pp. 229-237
-
-
Yamada, K.1
Imai, M.2
Yoshida, S.3
-
39
-
-
0026533435
-
Characterization of a novel aquaretic agent, OPC-31260, as an orally effective, nonpeptide vasopressin V2 receptor antagonist
-
YAMAMURA, Y., OGAWA, H., YAMASHITA, H., CHIHARA, T., MIYAMOTO, H., NAKAMURA, S., ONOGAWA, T., YAMASHITA, T., HOSOKAWA, T., MORI, T., TOMINAGA, M. AND YABUUCHI, Y.: Characterization of a novel aquaretic agent, OPC-31260, as an orally effective, nonpeptide vasopressin V2 receptor antagonist. Br. J. Pharmacol. 105: 787-791, 1992.
-
(1992)
Br. J. Pharmacol.
, vol.105
, pp. 787-791
-
-
Yamamura, Y.1
Ogawa, H.2
Yamashita, H.3
Chihara, T.4
Miyamoto, H.5
Nakamura, S.6
Onogawa, T.7
Yamashita, T.8
Hosokawa, T.9
Mori, T.10
Tominaga, M.11
Yabuuchi, Y.12
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