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Volumn 11, Issue 1, 1997, Pages 51-56

XR5118, a novel modulator of plasminogen activator inhibitor-1 (PAI-1 ), increases endogenous tPA activity in the rat

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG; XR 5118;

EID: 0030904328     PISSN: 13690191     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0268-9499(97)80009-4     Document Type: Article
Times cited : (28)

References (22)
  • 1
    • 0028786263 scopus 로고
    • Structure of plasminogen activator inhibitor 1 (PAI-1) and its function in fibrinolysis: An update
    • Van Meijer M, Pannekoek H. Structure of plasminogen activator inhibitor 1 (PAI-1) and its function in fibrinolysis: an update. Fibrinolysis 1995; 9: 263-276.
    • (1995) Fibrinolysis , vol.9 , pp. 263-276
    • Meijer, M.1    Pannekoek, H.2
  • 2
    • 0028206262 scopus 로고
    • The serpin superfamily of proteinase inhibitors: Structure, function, and regulation
    • Potempa J, Korzus E, Travis J. The serpin superfamily of proteinase inhibitors: structure, function, and regulation. J Biol Chem 1994; 269: 15957-15960.
    • (1994) J Biol Chem , vol.269 , pp. 15957-15960
    • Potempa, J.1    Korzus, E.2    Travis, J.3
  • 3
    • 0028937232 scopus 로고
    • Conformational studies on plasminogen activator inhibitor (PAI-1) in active, latent, substrate and cleaved forms
    • Sancho E, Declerck P J, Price N C, Kelly S M, Booth N A. Conformational studies on plasminogen activator inhibitor (PAI-1) in active, latent, substrate and cleaved forms. Biochemistry 1995; 34: 1064-1069.
    • (1995) Biochemistry , vol.34 , pp. 1064-1069
    • Sancho, E.1    Declerck, P.J.2    Price, N.C.3    Kelly, S.M.4    Booth, N.A.5
  • 4
    • 0026526006 scopus 로고
    • Plasminogen activator inhibitor type 1 : Biochemistry and evidence for modulation of fibrinolysis in vivo
    • Krishnamurti C, Alving B M. Plasminogen activator inhibitor type 1 : biochemistry and evidence for modulation of fibrinolysis in vivo. Sem Thromb Hemost 1992; 18: 67-80.
    • (1992) Sem Thromb Hemost , vol.18 , pp. 67-80
    • Krishnamurti, C.1    Alving, B.M.2
  • 5
    • 0027431075 scopus 로고
    • Attenuation of thrombolysis by release of plasminogen activator inhibitor type-1 from platelets
    • Torr-Brown S R, Sobel B E. Attenuation of thrombolysis by release of plasminogen activator inhibitor type-1 from platelets. ThrombRes 1993; 72: 413-421.
    • (1993) ThrombRes , vol.72 , pp. 413-421
    • Torr-Brown, S.R.1    Sobel, B.E.2
  • 6
    • 0027933421 scopus 로고
    • Plasminogen activator inhibitor-1 released from activated platelets plays a key role in thrombolysis resistance
    • Stringer H A, Van Swieten P, Heijnen H F G, Sixma J J, Pannekoek H. Plasminogen activator inhibitor-1 released from activated platelets plays a key role in thrombolysis resistance. Arterioscler Thromb 1994; 14: 1452-1458.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1452-1458
    • Stringer, H.A.1    Van Swieten, P.2    Heijnen, H.F.G.3    Sixma, J.J.4    Pannekoek, H.5
  • 7
    • 0025371467 scopus 로고
    • Development of venous occlusions in mice transgenic for the plasminogen activator inhibitor-1 gene
    • Erickson L A, Fici G J, Lund J E, Boyle T P, Polites H G, Marotti K R. Development of venous occlusions in mice transgenic for the plasminogen activator inhibitor-1 gene. Nature 1990; 346: 74-76.
    • (1990) Nature , vol.346 , pp. 74-76
    • Erickson, L.A.1    Fici, G.J.2    Lund, J.E.3    Boyle, T.P.4    Polites, H.G.5    Marotti, K.R.6
  • 9
    • 0026538755 scopus 로고
    • Familial thrombophilia associated with high levels of plasminogen activator inhibitor
    • Patrassi G M, Sartori M T, Saggiorato G, Boeri G, Girolami A. Familial thrombophilia associated with high levels of plasminogen activator inhibitor. Fibrinolysis 1992; 6: 99-103.
    • (1992) Fibrinolysis , vol.6 , pp. 99-103
    • Patrassi, G.M.1    Sartori, M.T.2    Saggiorato, G.3    Boeri, G.4    Girolami, A.5
  • 10
    • 0026713962 scopus 로고
    • The status of PAI-1 as a risk factor for arterial and thrombotic disease: A review
    • Dawson S, Henney A. The status of PAI-1 as a risk factor for arterial and thrombotic disease: a review. Atherosclerosis 1992; 95: 105-117.
    • (1992) Atherosclerosis , vol.95 , pp. 105-117
    • Dawson, S.1    Henney, A.2
  • 11
    • 0027933555 scopus 로고
    • Role of plasminogen activator inhibitor type 1 in the pathogenesis of coronary artery diseases
    • Aznar J, Estellés A. Role of plasminogen activator inhibitor type 1 in the pathogenesis of coronary artery diseases. Haemostasis 1994; 24: 243-251.
    • (1994) Haemostasis , vol.24 , pp. 243-251
    • Aznar, J.1    Estellés, A.2
  • 12
    • 0027511652 scopus 로고
    • Plasminogen activator inhibitor: A risk factor for myocardial infarction in diabetic patients
    • Gray R P, Yudkin J S, Patterson L. Plasminogen activator inhibitor: a risk factor for myocardial infarction in diabetic patients. Br Heart J 1993; 69: 228-232.
    • (1993) Br Heart J , vol.69 , pp. 228-232
    • Gray, R.P.1    Yudkin, J.S.2    Patterson, L.3
  • 14
    • 0026597817 scopus 로고
    • Inhibition of plasminogen activator inhibitor-1 activity results in promotion of endogenous thrombolysis and inhibition of thrombus extension in models of experimental thrombosis
    • Levi M, Biemond B J, Van Zonneveld A-J, Ten Gate J W, Pannekoek H. Inhibition of plasminogen activator inhibitor-1 activity results in promotion of endogenous thrombolysis and inhibition of thrombus extension in models of experimental thrombosis. Circulation 1992; 85: 305-312.
    • (1992) Circulation , vol.85 , pp. 305-312
    • Levi, M.1    Biemond, B.J.2    Van Zonneveld, A.-J.3    Ten Gate, J.W.4    Pannekoek, H.5
  • 15
    • 0028909718 scopus 로고
    • Thrombolysis and reocclusion in experimental jugular vein and coronary artery thrombosis
    • Biemond B J, Levi M, Coronel R, Janse M J, Ten Gate J W, Pannekoek H. Thrombolysis and reocclusion in experimental jugular vein and coronary artery thrombosis. Circulation 1995; 91: 1175-1181.
    • (1995) Circulation , vol.91 , pp. 1175-1181
    • Biemond, B.J.1    Levi, M.2    Coronel, R.3    Janse, M.J.4    Ten Gate, J.W.5    Pannekoek, H.6
  • 17
    • 0027223957 scopus 로고
    • The potential role of platelet PAI-1 in tPA-mediated clot lysis of platelet rich plasma
    • Serizawa K, Uranto T, Kozima Y, Takada Y, Takaka A. The potential role of platelet PAI-1 in tPA-mediated clot lysis of platelet rich plasma. Thromb Res 1993; 71: 289-300.
    • (1993) Thromb Res , vol.71 , pp. 289-300
    • Serizawa, K.1    Uranto, T.2    Kozima, Y.3    Takada, Y.4    Takaka, A.5
  • 19
    • 0024408538 scopus 로고
    • Blood collection in strong acidic anticoagulant used in a study of dietary influence on basal tPA activity
    • Rânby M, Sundell I B, Nilsson T K. Blood collection in strong acidic anticoagulant used in a study of dietary influence on basal tPA activity. Thromb Haemost 1989; 62: 917-922.
    • (1989) Thromb Haemost , vol.62 , pp. 917-922
    • Rânby, M.1    Sundell, I.B.2    Nilsson, T.K.3
  • 20
    • 0015247211 scopus 로고
    • Experimental arterial thrombosis in rats with continuous registration
    • Hladovec J. Experimental arterial thrombosis in rats with continuous registration. Thromb Diath Haemostr 1971; 26: 407-410.
    • (1971) Thromb Diath Haemostr , vol.26 , pp. 407-410
    • Hladovec, J.1
  • 21
    • 8944259267 scopus 로고
    • Determinants of the dilute whole blood clot lysis time (DCLT)
    • MacCallum P K, Meade T W, Howath D J. Determinants of the dilute whole blood clot lysis time (DCLT). Brit J Haemotol 1995; 89(Suppl 1): 28a.
    • (1995) Brit J Haemotol , vol.89 , Issue.1 SUPPL.
    • MacCallum, P.K.1    Meade, T.W.2    Howath, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.