Determination of residual amines used in bulk drug synthesis by pre-column derivatization with 3,5-dinitrobenzoyl chloride and high-performance liquid chromatography

Journal of Chromatography A

Volumn 766, Issue 1-2, 1997, Pages 77-83

  Morley, James ^a   Elrod Jr , Lee ^a   Linton, Cathie ^a   Shaffer, Dean ^a   Krogh, Suzanne ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Amines; Derivatization, LC; Enantiomer separation; Pharmaceutical analysis

Indexed keywords

2 METHYLPIPERAZINE; AMINE; PIPERAZINE; PIPERAZINE DERIVATIVE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DETERMINATION; DRUG MANUFACTURE; DRUG PURITY; DRUG SYNTHESIS; ENANTIOMER; PRIORITY JOURNAL; TECHNIQUE;

EID: 0030903995     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(96)01058-8     Document Type: Article

References (21)

1. Y-M. Mei, J. Liq. Chromatogr., 17 (1994) 2413.
2. S. Wongyai, P.J. Oefner and G.K. Bonn, J. Liq. Chromatogr., 12 (1989) 2249.
3. E.S. Barreira, J.P. Parente and J. Wilson de Alencar, J. Chromatogr., 398 (1987) 381.
4. J.W. Redmond and A. Tseng, J. Chromatogr., 170 (1979) 479.
5. W.H. Pirkle and M.H. Hyun, J. Org. Chem., 49 (1984) 3043.
6. M.H. Hyun and M-S. Kim, Bull, Kor. Chem. Soc., 12 (1991) 104.
7. R. Dappen, V.R. Meyer and H. Arm, J. Chromatogr., 295 (1984) 367.
8. D. Uzunov and G. Stoev, J. Chromatogr., 645 (1993) 233.
9. A.J. Bourque and I.S. Krull, J. Chromatogr., 537 (1991) 123.
10. Y. Tang, Y Zhou and D.W. Armstrong, J. Chromatogr. A, 666 (1994) 147.
11. A. Tambute, A. Bergos, M. Lienne, M. Caude and R. Rosset, J. Chromatogr., 396 (1987) 65.
12. W.H. Pirkle and T.J. Sowin, J. Chromatogr., 396 (1987) 83.
13. W.H. Pirkle, M.H. Hyun and B. Bank, J. Chromatogr., 316 (1984) 585.
14. J.F. Lawrence and R.W. Frei, Chemical Derivatization in Liquid Chromatography, Elsevier, Amsterdam, 1977.
15. I.S. Krull, Z. Deyl and H. Lingeman, J. Chromatogr. B, 659 (1994) 1.
16. S. Gorog and M. Gazdag, J. Chromatogr. B, 659 (1994) 51.
17. K. Jedrzejczak and V.S. Gaind, Analyst, 118 (1993) 1383.
18. H. Kataoka, M. Eda and M. Makita, Biomed. Chromatogr., 7 (1993) 129.
19. T. Trukioka, H. Ozawa and T. Murakami, J. Chromatogr., 642 (1993) 395.
20. L. Elrod, L.B. White, S.G. Spanton, D.G. Stroz, P.J. Cugier and L.A. Luka, Anal. Chem., 56 (1984) 1786.
21. J.P. Sanchez, J.M. Domagala, C.L. Heifetz, S.R. Priebe, J.A. Sensie and A.K. Trehan, J. Med. Chem., 35 (1992) 1764.