Azido acids in a novel method of solid-phase peptide synthesis

Tetrahedron Letters

Volumn 38, Issue 14, 1997, Pages 2531-2534

  Meldal, Morten ^a   Juliano, Maria A ^a   Jansson, Anita M ^a  

^a CARLSBERG LABORATORY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; AZIDE; PEPTIDE;

ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDE SYNTHESIS; REACTION ANALYSIS;

EID: 0030903994     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00393-6     Document Type: Article

References (19)

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18. 3 can detonate when handled in the purified form and should always be prepared and used in situ as a solution.
19. When performing the reduction at a more elevated temperature (55-60 °C, 1h), about 5% of racemization was observed for the short peptide 12.