Physiological evidence for hippocampal disinhibition resulting from activation of the median raphe

Brain Research

Volumn 752, Issue 1-2, 1997, Pages 90-98

  Kao, Kuen ^a   Sanders, Matthew J ^a   Green, Edward J ^a  

^a UNIVERSITY OF MIAMI   (United States)

Author keywords

dentate gyrus; field potential; interneuron; population spike; single unit

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; HISTOLOGY; INTERNEURON; MALE; NONHUMAN; PRIORITY JOURNAL; RAPHE NUCLEUS; RAT; SINGLE UNIT ACTIVITY;

ANIMALS; DENTATE GYRUS; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; HIPPOCAMPUS; HOMOCYSTEINE; INTERNEURONS; MALE; NEURAL INHIBITION; RAPHE NUCLEI; RATS; RATS, INBRED STRAINS; STIMULATION, CHEMICAL;

EID: 0030903542     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01455-2     Document Type: Article

References (44)

1. Alreja, M., Excitatory actions of serotonin on GABAergic neurons of the medial septum and diagonal band of broca, Synapse, 22 (1996) 15-27.
2. Alvarez-Leefmans, F.J. and Gardner-Medwin, A.R., Influences of the septum on the hippocampal dentate area which are unaccompanied by field potentials, J. Physiol., 249 (1975) 14P-16P.
3. Assaf, S.Y. and Miller, J.J., Neuronal transmission in the dentate gyrus: role of inhibitory mechanisms. Brain Res., 151 (1978) 587-592.
4. Azmitia, E.C., Bilateral serotonergic projections to the dorsal hippocampus of the rat: simultaneous localization of 3H-5HT and HRP after retrograde transport, J. Comp. Neurol., 203 (1981) 737-743.
5. Azmitia, E.C. and Segal, M., An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat, J. Comp. Neurol., 179 (1978) 641-668.
6. Bilkey, D.K. and Goddard, G.V., Medial septal facilitation of hippocampal granule cell activity is mediated by inhibition of inhibitory interneurons, Brain Res., 361 (1985) 99-106.
7. Buckmaster, P.S. and Schwartzkroin, P.A., Interneurons and inhibition in the dentate gyrus of the rat in vivo, J. Neurosci., 15 (1995) 774-789.
8. Buzsaki, G. and Eidelberg, E., Direct afferent excitation and long-term potentiation of hippocampal interneurons, J. Neurophysiol., 48 (1982) 597-607.
9. Conrad, L.C., Leonard, C.M. and Pfaff, D.W., Connections of the median and dorsal raphe nuclei in the rat: an autoradiographic and degeneration study, J. Comp. Neurol., 156 (1979) 179-206.
10. Crunelii, V. and Segal, M., An electrophysiological study of neurones in the rat median raphe and their projections to septum and hippocampus. Neuroscience, 15 (1985) 47-60.
11. Dahl, D., Bailey, W.H. and Winson, J., Effect of norepinephrine depletion of hippocampus on neuronal transmission from perforant pathway through dentate gyrus, J. Neurophysiol., 49 (1983) 123-133.
12. Fantie, B.D. and Goddard, G.V., Septal modulation of the population spike in the fascia dentata produced by perforant path stimulation in the rat, Brain Res., 252 (1982) 227-237.
13. Feldman, R.S. and Quenzer, L.F., Fundamentals of Neuropsychopharmacology, Sinauer, MA, 1984, p. 286.
14. Fox, S.E. and Ranck, J.B., Electrophysiological characteristics of hippocampal complex-spike and theta cells, Exp. Brain Res., 41 (1981) 399-410.
15. Freund, T.F., GABAergic septal and serotonergic median raphe afferents preferentially innervate inhibitory interneurons in the hippocampus and dentate gyrus. In C.E. Ribak, C.M. Gall and I. Mody (Eds.), The Dentate Gyrus and Its Role in Seizures, Epilepsy Res. Suppl., 7 (1992) 79-91, Elsevier, Amsterdam, The Netherlands.
16. Freund, T.F. and Antal, M., GABA-containing neurons in the septum control inhibitory interneurons in the hippocampus, Nature, 336 (1988) 170-173.
17. Freund, T.F., Gulyas, A.I., Acsady, L., Gores, T. and Toth, K., Serotonergic control of the hippocampus via local inhibitory interneurons, Proc. Natl. Acad. Sci. USA, 87 (1990) 8501-8505.
18. Fricke, R.A. and Prince, D.A., Electrophysiology of dentate gyrus granule cells, J. Neurophysiol., 51 (1984) 195-209.
19. Ghadimi, B.M., Jarolimek, W. and Misgeld, U., Effects of serotonin on hilar neurons and granule cell inhibition in the guinea pig hippocampal slice, Brain Res., 633 (1994) 27-32.
20. Green, E.J., Barnes, C.A. and McNaughton, B.L., Behavioral state dependence of homo- and hetero-synaptic modulation of dentate gyrus excitability, Exp. Brain Res., 93 (1993) 55-65.
21. Halasy, K., Miettinen, R., Szabat, E. and Freund, T.F., GABAergic interneurons are the major postsynaptic targets of median raphe afferents in the rat dentate gyrus, Eur. J. Neurosci., 4 (1992) 144-153.
22. Jung, M.W. and McNaughton, B.L., Spatial selectivity of unit activity in the hippocampal granular layer. Hippocampus, 3 (1993) 165-182.
23. Klancnik, J.M. and Phillips, A.G., Modulation of synaptic plasticity in the dentate gyrus of the rat by electrical stimulation of the median raphe nucleus, Brain Res., 557 (1991) 236-240.
24. Kohler, C. and Steinbusch, H., Identification of serotonin and non-serotonin-containing neurons of the mid-brain raphe projecting to the entorhinal area and the hippocampal formation. A combined immunohistochemical and fluorescent retorgrade tracing study in the rat, Neuroscience, 7 (1982) 951-975.
25. Krnjevic, K., Ropert, N. and Casullo, J., Septohippocampal disinhibition, Brain Res., 438 (1988) 182-192.
26. Lambert, J. and Jones, R.S.G., A re-evaluation of excitatory amino acid-mediated synaptic transmission in the rat dentate gyrus in vitro, Neurosci. Lett., 64 (1990) 119-132.
27. McNaughton, B.L., O'Keefe, J. and Barnes, C.A., The stereotrode: a new technique for simultaneous isolation of several single units in the central nervous system from multiple unit records, J. Neurosci. Methods, 8 (1983) 391-397.
28. Milner, T.A. and Veznedaroglu, E., Serotonin-containing terminals synapse on septohippocampal neurons in the rat, J. Neurosci. Res., 36 (1993) 260-271.
29. Mietten, R. and Freund, T.F., Convergence and segregation of septal and median raphe inputs onto different subsets of hippocampal inhibitory interneurons, Brain Res., 594 (1992) 263-272.
30. Mizumori, S.J.Y., McNaughton, B.L. and Barnes, C.A., A comparison of supramammillary and medial septal influences on hippocampal field potentials and single-unit activity, J. Neurophysiol., 61 (1989) 15-31.
31. Moore, R.Y. and Halaris, A.E., Hippocampal innervation by serotonin neurons of the midbrain raphe in the rat, J. Comp. Neurol., 164 (1975) 171-184.
32. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, NY, 1986.
33. Richter-Levin, G. and Segal, M., Effect of serotonin releasers on dentate granule cell excitability in the rat, Exp. Brain Res., 82 (1990) 199-207.
34. Ropert, N. and Guy, N., Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro, J. Physiol., 441 (1991) 121-136.
35. Scharfman, H.E., Differentation of rat dentate neurons by morphology and electrophysiology in hippocampal slices: granule cells, spiny hilar cells and aspiny 'fast spiking' cells, Epilepsy Res. Suppl., 7 (1992) 93-109.
36. Segal, M., Physiological and pharmacological evidence for a serotonergic projection to the hippocampus. Brain Res., 94 (1975) 115-131.
37. Segal, M., Serotonin attenuates a slow inhibitory postsynaptic potential in rat hippocampal neurons, Neuroscience, 36 (1990) 631-641.
38. Sloviter, R.S. and Connor, J.D., Effect of raphe stimulation on granule cell activity in the hippocampal dentate gyrus, Soc. Neurosci. Abstr., 5 (1979) p. 282.
39. Srebro, B., Azmitia, E.C. and Winson, J., Effect of 5-HT depletion of the hippocampus on neuronal transmission from perforant path through dentate gyrus, Brain Res., 235 (1982) 142-147.
40. Staley, K.J., Otis, T.S. and Mody, I., Membrane properties of dentate gyrus granule cells: comparison of sharp microelectrode and whole cell patch recordings, J. Neurophysiol., 68 (1992) 1346-1358.
41. Tomasulo, R.A. and Steward, O., Homosynaptic and heterosynaptic changes in driving of dentate gyrus interneurons after brief tetanic stimulation in vivo, Hippocampus, 6 (1996) 62-71.
42. Winson, J., Influence of raphe nuclei on neuronal transmission from perforant pathway through dentate gyrus, J. Neurophysiol., 44 (1980) 937-950.
43. Winson, J., Reticular formation influence on neuronal transmission from perforant pathway through dentate gyrus, Brain Res., 225 (1981) 37-49.
44. Ylinen, A., Soltesz, I., Bragin, A., Penttonen, M., Sik, A. and Buzsaki, G., Intracellular correlates of hippocampal theta rhythm in identified pyramidal cells, granule cells, and basket cells, Hippocampus, 5 (1995) 78-90.