Effects of σ ligands on the nociceptin/orphanin FQ receptor co-expressed with the G-protein-activated K+ channel in Xenopus oocytes

British Journal of Pharmacology

Volumn 120, Issue 6, 1997, Pages 986-987

  Kobayashi, Toru ^a,b   Ikeda, Kazutaka ^c   Togashi, Shunji ^b   Itoh, Noboru ^b   Kumanishi, Toshiro ^a  

^a NIIGATA UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

ligand; Carbetapentane; G protein activated inwardly rectifying K+ (GIRK) channel; Nociceptin orphanin FQ receptor; Rimcazole; Xenopus oocyte

Indexed keywords

1,3 BIS(2 METHYLPHENYL)GUANIDINE; CYCLAZOCINE; GUANIDINE DERIVATIVE; GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; MESSENGER RNA; N ALLYLNORMETAZOCINE; NOCICEPTIN; NOCICEPTIN RECEPTOR; ORPHANIN; PENTOXYVERINE; POTASSIUM CHANNEL; POTASSIUM ION; PRECLAMOL; RECEPTOR; RIMCAZOLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; NOCICEPTION; NONHUMAN; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOPUS;

ANIMALS; CARBAZOLES; CYCLOPENTANES; GTP-BINDING PROTEINS; OOCYTES; OPIOID PEPTIDES; POTASSIUM CHANNELS; RATS; RECEPTORS, OPIOID; RECEPTORS, SIGMA; XENOPUS;

EID: 0030903527     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701068     Document Type: Article

References (10)

1. DAVIDSON, J., MILLER, R., WINGFIELD, M., ZUNG, W. & DREN, A.T. (1982). The first clinical study of BW-234U in schizophrenia. Psychopharmacol. Bull., 18, 173-176.
2. 1 muscarinic antagonists interact with σ recognition sites. Life Sci., 49, 1229-1235.
3. + (GIRK) channel. Mol. Brain Res., (in press).
4. + (GIRK) channel in Xenopus oocytes. Br. J. Pharmacol., 119, 73-80.
5. 1 receptor. Nature, 377, 532-535.
6. MOLLEREAU, C., PARMENTIER, M., MAILLEUX, P., BUTOUR, J.-L., MOISAND, C., CHALON, P., CAPUT, D., VASSART, G. & MEUNIER, J.-C. (1994). ORL1, a novel member of the opioid receptor family: cloning, functional expression and localization. FEBS Lett., 341, 33-38.
7. REINSCHEID, R.K., NOTHACKER, H.-P., BOURSON, A., ARDATI, A., HENNINGSEN, R.A., BUNZOW, J.R., GRANDY, D.K., LANGEN, H., MONSMA, F.J. Jr. & CIVELLI, O. (1995). Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science, 270, 792-794.
8. STANFA, L.C., CHAPMAN, V., KERR, N. & DICKENSON, A.H. (1996). Inhibitory action of nociceptin on spinal dorsal horn neurones of the rat, in vivo. Br. J. Pharmacol., 118, 1875-1877.
9. SU, T.-P. (1993). Delineating biochemical and functional properties of sigma receptors: emerging concepts. Crit. Rev. Neurobiol., 7, 187-203.
10. WALKER, J.M., BOWEN, W.D., WALKER, F.O., MATSUMOTO, R.R., DE COSTA, B. & RICE, K.C. (1990). Sigma receptors: biology and function. Pharmacol. Rev., 42, 355-402.