-
1
-
-
85114532558
-
-
Baba, M., Mori, S., Shigeta, S. and De Clercq, E. (1987) Selective inhibitory effect of (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 2′-nor-cyclic GMP on adenovirus replication in vitro. Antimicrob. Agents Chemother. 31, 337–339.
-
-
-
-
2
-
-
85114544414
-
-
Balzarini, J., Baba, M., Pauwels, R., Herdewijn, P., Wood, S.G., Robins, M.J. and DeClercq, E. (1988) Potent and selective activity of 3′-azido-2,6-diaminopurine-2′,3′-dideoxyriboside, 3′-fluoro-2,6-diaminopurine-2′,3′-dideoxyriboside, and 3′-fluoro-2′,3′-dideoxyguanosine against human immunodeficiency virus. Mol. Pharmacol. 33, 243–249.
-
-
-
-
3
-
-
85114541712
-
-
Chu, C.K.V., Bhadti, S., Doboszewski, B., Gu, Z.G., Kosugi, Y., Pullaiah, K.C. and van Roey, P. (1989) General synthesis of 2′,3′-dideoxynucleosides and 2′,3′-didehydro-2′,3′-dideoxynucleosides. J. Org. Chem. 54, 2217–2225.
-
-
-
-
4
-
-
85114538775
-
-
Cotton, M. and Weber, J.M. (1995) The adenovirus protease is required for virus entry into host cells. Virology 213, 494–502.
-
-
-
-
5
-
-
85114525140
-
-
De Clercq, E. (1990) Selective virus inhibitors. Microbiologica 13, 165–178.
-
-
-
-
6
-
-
85114540565
-
-
De Clercq, E. (1993) Antiviral agents: Characteristic activity spectrum depending on the molecular target with which they interact. In: Advances in Virus Research, Vol. 42, Academic Press, New York.
-
-
-
-
7
-
-
85114523036
-
-
De Oliveira, C.B.R., Stevenson, D., La Bree, L., McDonnell, P.J. and Trousdale, M.D. (1996) Evaluation of cidofovir (HPMPC, GS-504) against adenovirus type 5 infection in vitro and in a New Zealand rabbit ocular model. Antiviral Res. 31, 165–172.
-
-
-
-
8
-
-
85114530553
-
-
Gordon, Y.J., Romanowski, E., Araullo-Cruz, T., Seaberg, L., Erzurum, S., Tolman, R. and De Clercq, E. (1991) Inhibitory effect of (S)-HPMPC, (S)- HPMPA, and 2′-norcyclic GMP on clinical ocular adenoviral isolates is serotype-dependent in vitro. Antiviral Res. 16, 11–16.
-
-
-
-
9
-
-
85114524467
-
-
Hafkemeyer, P., Keppler-Hafkemeyer, A., Abo Al Haya, M., Janta-Lipinski, M., Matthes, E., Lehmann, C., Offensperger, W.-B., Offensperger, S., Gerok, W. and Blum, H.E. (1996) Inhibition of duck hepatitis B virus replication by 2′,3′-dideoxy-3′-fluoroguanosine in vitro and in vivo. Antimicrob. Agents Chemother. 40, 792–794.
-
-
-
-
10
-
-
85114524438
-
-
Herdewijn, P., van Aerschot, A. and Kerremans, L. (1989) Synthesis of nucleosides fluorinated in the sugar moiety. The application of diethylaminosulfurtrifluoride to the synthesis of fluorinated nucleosides. Nucleosides Nucleotides 8, 65–96.
-
-
-
-
11
-
-
85114551110
-
-
Hui, M.B.V., Lien, E.J. and Trousdale, M.D. (1994) Inhibition of human adenoviruses by 1-(2′-hydroxy-5′-methoxybenzylidene) amino-3-hydroxyguanidine tosylate. Antiviral Res. 24, 261–273.
-
-
-
-
12
-
-
85114534889
-
-
Jackson, R., Morris, D.J., Cooper, R.J., Bailey, A.S., Klapper, P.E., Cleator, G.M. and Tullo, A.B. (1996) Multiplex polymerase chain reaction for adenovirua and herpes simplex virus in eye swabs. J. Virol. Methods 56, 41–48.
-
-
-
-
13
-
-
85114542631
-
-
Jernigan, J.A., Lowry, B.S., Hayden, F.G., Kyger, S.A., Conway, B.P., Gröschel, D.H.M. and Farr, B.M. (1993) Adenovirus type 8 epidemic keratoconjunctivitis in an eye clinic: risk factors and control. J. Infect. Dis. 167, 1307–1313.
-
-
-
-
14
-
-
85114545600
-
-
Kodama, E., Shigeta, S., Suzuki, T. and DeClercq, E. (1996) Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method. Antiviral Res. 31, 159–164.
-
-
-
-
15
-
-
85114541903
-
-
Kowollik, G., Etzold, G., von Janta-Lipinski, M., Gaertner, K. and Langen, P. (1973) Ein neuer Zugang zu 1-(2,3-Dideoxy-3-fluor–D-ribofuranosyl)-pyrimidinen. J. Prakt. Chem. 315, 895–900.
-
-
-
-
16
-
-
85114535428
-
-
Matsuse, T., Matsui, H., Shu, C.-Y, Nagase, T., Wakabayashi, T., Mori, S., Inoue, S., Fukuchi, Y. and Orimo, H. (1994) Adenovirus pulmonary infections identified by PCR and in situ hybridisation in bone marrow transplant recipients. J. Clin. Pathol. 47, 973–977.
-
-
-
-
17
-
-
85114544484
-
-
Matthes, E., Lehmann, Ch., Scholz, D., von Janta-Lipinski, M., Gärtner, R., Rosenthal, H.A. and Langen, P. (1987) Inhibition of HIV-associated reverse transcriptase by sugar-modified derivatives of thymidine 5′- triphosphate in comparison to cellular DNA polymerases α and β . Biochem. Biophys. Res. Commun. 148, 78–85.
-
-
-
-
18
-
-
85114544403
-
-
Matthes, E., Lehmann, Ch., Scholz, D., Rosenthal, H.A. and Langen, P. (1988) Phosphorylation, anti-HIV activity and cytotoxicity of 3′-′- fluorothymidine. Biochem. Biophys. Res. Commun. 153, 825–831.
-
-
-
-
19
-
-
85114531349
-
-
Matthes, E., Langen, P., von Janta-Lipinski, M., Will, H., Schröder, H.C., Merz, H., Weiler, B.E. and Müller, W.E.G. (1990) Potent inhibition of hepatitis B virus production in vitro by modified pyrimidine nucleosides. Antimicrob. Agents Chemother. 34, 1986–1990.
-
-
-
-
20
-
-
85114528834
-
-
Matthes, E., Reimer, K., von Janta-Lipinski, M., Meisel, H. and Lehmann, C. (1991) Comparative inhibition of hepatitis B virus DNA polymerase and cellular DNA polymerases by triphosphates of sugar-modified 5′-methyldeoxycytidines and of other nucleoside analogs. Antimicrob. Agents Chemother. 35, 1254–1257.
-
-
-
-
21
-
-
85114532481
-
-
Meisel, H., Reimer, K., von Janta-Lipinski, M., Bärwolff, D. and Matthes, E. (1990) Inhibition of hepatitis B-virus DNA-polymerase by 3′-fluorothymidine nucleoside triphosphate and other modified nucleoside triphosphate analogs. J. Med. Virol. 301, 137–141.
-
-
-
-
22
-
-
85114546902
-
-
Mentel, R., Jacker, S. and Wegner, U. (1993) Studies on the development of an adenovirus infection model in hamsters. Hyg. Med. 18, 489–493.
-
-
-
-
23
-
-
85114535471
-
-
Mentel, R., Matthes, E., von Janta-Lipinski, M. and Wegner, U. (1996) Fluorescent focus reduction assay for the screening of antiadenoviral agents. J. Virol. Methods 59, 99–104.
-
-
-
-
24
-
-
85114533841
-
-
Schinazi, R.F., Mead, J.R. and Feorino, P.M. (1992) Insights into HIV chemotherapy. AIDS Res. Hum. Retrovir. 8, 963–990.
-
-
-
-
25
-
-
85114523865
-
-
Suzuki, S., Lee, B., Luo, W., Robins, M.J. and Tyrrell, D.L.J. (1988) Inhibition of duck hepatitis B virus replication by purine 2′,3′-dideoxynucleosides. Biochem. Biophys. Res. Commun. 156, 1144–1151.
-
-
-
-
26
-
-
85114544920
-
-
Van Aerschot, A., Herdewijn, P., Balzarini, J., Pauwels, R. and De Clercq, E. (1989) 3′-Fluoro-2′,3′-dideoxy-5-chlorouridine: Most selective anti-HIV-1 agent among a series of new 2′-and 3′-fluorinated 2′,3′-dideoxynucleoside analogues. J. Med. Chem. 32, 1743–1749.
-
-
-
-
27
-
-
85114550418
-
-
Wold, W.S.M. and Gooding, L.R. (1991) Region E3 of adenovirus: a cassette of genes involved in host immunosurveillance and virus-cell interactions. Virology 184, 1–8.
-
-
-
|