Synthesis of new tetrahydropyrazine and other heterocyclic compounds by reaction of hydrazonoyl chlorides

Archiv der Pharmazie

Volumn 330, Issue 3, 1997, Pages 47-52

  Frohberg, Petra ^a   Wiese, Michael ^a   Nuhn, Peter ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

1,4 benzothiazine; inhibitors; lipoxygena se (LO); quinoxaline; tetrahydropyrazine

Indexed keywords

1,3,4 THIADIAZOLE DERIVATIVE; 3 AMINO 1 (3 TRIFLUOROMETHYLPHENYL) 2 PYRAZOLINE; 4 [2 (3 CHLOROPHENYL)HYDRAZONO 2H 1,4 BENZOTHIAZIN 3 YL]BUTYRIC ACID METHYL ESTER; 4 [2 (4 CHLOROPHENYL)HYDRAZONO 1,2,5,6 TETRAHYDROPYRAZIN 3 YL]BUTYRIC ACID METHYL ESTER; ARACHIDONATE 5 LIPOXYGENASE; CGS 22745; ENZYME INHIBITOR; LEUKOTRIENE B4; PYRAZINE DERIVATIVE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; ARACHIDONATE 15 LIPOXYGENASE; HETEROCYCLIC COMPOUND; LIPOXYGENASE INHIBITOR; PIPERAZINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; NEUTROPHIL; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REACTION ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROPHOTOMETRY; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; SYNTHESIS;

ARACHIDONATE 15-LIPOXYGENASE; ARACHIDONATE 5-LIPOXYGENASE; HETEROCYCLIC COMPOUNDS; HUMANS; LEUKOTRIENE B4; LIPOXYGENASE INHIBITORS; MOLECULAR STRUCTURE; NEUTROPHILS; PIPERAZINES; PYRAZINES;

EID: 0030902372     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.19973300302     Document Type: Article

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