Evidence that the eosinophil is a cellular target for the inhibitory action of salmeterol on eosinophil recruitment in vivo

European Journal of Pharmacology

Volumn 323, Issue 2-3, 1997, Pages 255-260

  Teixeira, Mauro M ^a   Hellewell, Paul G ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

2 Adrenoceptor agonist; cAMP; Eosinophil; Eosinophil aggregation; Salmeterol

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; COMPLEMENT COMPONENT C5A; SALMETEROL; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL AGGREGATION; CONTROLLED STUDY; EOSINOPHIL; GUINEA PIG; NONHUMAN; PRIORITY JOURNAL; SKIN;

ADRENERGIC BETA-AGONISTS; ALBUTEROL; ANIMALS; CELL AGGREGATION; DEPRESSION, CHEMICAL; EOSINOPHILS; GUINEA PIGS; HUMANS; PLATELET ACTIVATING FACTOR; SKIN; ZYMOSAN;

EID: 0030901505     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)00030-7     Document Type: Article

References (25)

1. Backer, A.J. and R.W. Fuller, 1990, Anti-inflammatory effect of salmeterol on human alveolar macrophages, Am. Rev. Respir. Dis. 141, A394.
2. 2-adrenoceptor agonist: characterization of pharmacological activity in vitro and in vivo, Br. J. Pharmacol. 104, 665.
3. Butchers, P.R., C.J. Vardey and M. Johnson, 1991, Salmeterol: a potent and long-acting inhibitor of inflammatory mediator release from human lung, Br. J. Pharmacol. 104, 672.
4. Butterfield, J.H. and K.M. Leiferman, 1993, Eosinophil-associated diseases, in: Immunopharmacological of Eosinophils, eds. H. Smith and R.M. Cook (Academic Press, London) p. 152.
5. Church, M.K. and J. Hiroi, 1987, Inhibition of IgE-dependent histamine release from human dispersed lung mast cells by anti-allergic drugs and salbutamol, Br. J. Pharmacol. 90, 421.
6. Derian, C.K., R.J. Santulli, P.E. Rao, H.F. Solomon and J.A. Barrett, 1995, Inhibition of chemotactic peptide-induced neutrophil adhesion to vascular endothelium by cAMP modulators, J. Immunol. 154, 308.
7. 111In-eosinophils induced by inflammatory mediators in vivo, Immunology 73, 222.
8. Foster, P.S., S.P. Hogan, A.J. Ramsay, K.I. Matthaei and I.G. Young, 1996, Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model, J. Exp. Med. 183, 195.
9. Fugner, A., 1989, Formation of oedema and accumulation of eosinophils in the guinea pig lung. Inhibition by inhaled beta-stimulants, Int. Arch. Allergy Appl. Immunol. 88, 225.
10. Koenderman, L., T. Maikoe, R. Warringa and J. Raaijmakers, 1992, Salmeterol is a potent inhibitor of cytokine-primed eosinophil chemotaxis, Am. Rev. Respir. Dis. 145, A421.
11. Newsholme, S.J. and L. Schwartz, 1993, cAMP-specific phosphodiesterase inhibitor, rolipram, reduces eosinophil infiltration evoked by leukotrienes or by histamine in guinea pig conjunctiva, Inflammation 17, 25.
12. Ohman, J.L., M. Lawrence and F.C. Lowell, 1972, Effect of propranolol on the eosinopenic responses of cortisol, isoproterenol and aminophylline, J. Allergy Clin. Immunol. 50, 151.
13. Pober, J.S., M.R. Slowik, L.G. De Luca and A.J. Ritchie, 1993, Elevated cyclic AMP inhibits endothelial cell synthesis and expression of TNF-induced endothelial leukocyte adhesion molecule-1, and vascular cell adhesion molecule-1, but not intercellular adhesion molecule-1, J. Immunol. 150, 5114.
14. Sugiyama, H., C. Okada, A.K. Bewtra, R.J. Hopp and R.G. Townley, 1992, The effect of formoterol on the late asthmatic phenomena in guinea pigs, J. Allergy Clin. Immunol. 89, 858.
15. Teixeira, M.M., S. Reynia, M. Robinson, A. Shock, T.J. Williams, F.M. Williams, A.G. Rossi and P.G. Hellewell, 1994a, Role of CD18 in the accumulation of eosinophils and neutrophils and local oedema formation in inflammatory reactions in guinea pig skin, Br. J. Pharmacol. 111, 811.
16. Teixeira, M.M., A.G. Rossi, T.J. Williams and P.G. Hellewell, 1994b, Effects of phosphodiesterase isoenzyme inhibitors on cutaneous inflammation in the guinea-pig, Br. J. Pharmacol. 112, 332.
17. Teixeira, M.M., T.J. Williams, B.-T. Au, P.G. Hellewell and A.G. Rossi, 1995a, Characterisation of eosinophil homotypic aggregation, J. Leukocyte Biol. 57, 226.
18. Teixeira, M.M., T.J. Williams and P.G. Hellewell, 1995b, Mechanisms and pharmacological manipulation of eosinophil accumulation in vivo, Trends Pharmacol. Sci. 16, 418.
19. 2-adrenoceptor agonist in guinea pig skin, Eur. J. Pharmacol. 272, 185.
20. Teixeira, M.M., A.G. Rossi, M.A. Giembycz and P.G. Hellewell, 1996a, Effects of agents which elevate cyclic AMP on eosinophil homotypic aggregation, Br. J. Pharmacol. 118, 2099.
21. Teixeira, M.M., A.G. Rossi and P.G. Hellewell, 1996b, Adhesion mechanisms involved in C5a-induced eosinophil homotypic aggregation, J. Leukocyte Biol. 59, 389.
22. Ting, S., B. Zweiman and R. Lavker, 1983, Terbutaline modulation of human allergic skin reaction, J. Allergy Clin. Immunol. 71, 437.
23. Underwood, D.C., R.R. Osborn, L.B. Novak, J.K. Matthews, S.J. Newsholme, B.J. Undem, J.M. Hand and T.J. Torphy, 1993, Inhibition of antigen-induced bronchoconstriction and eosinophil infiltration in the guinea pig by the cyclic AMP-specific phosphodiesterase inhibitor, rolipram, J. Pharmacol. Exp. Ther. 266, 306.
24. Weller, P.F., 1991, The immunobiology of eosinophils, New Engl. J. Med. 324, 1110.
25. Whelan, C.J., M. Johnson and C.J. Vardey, 1993, Comparison of the anti-inflammatory properties of formoterol, salbutamol and salmeterol in guinea-pig skin and lung, Br. J. Pharmacol. 110, 613.