Gas phase hydrogen/deuterium exchange reactions of peptide ions in a quadrupole ion trap mass spectrometer

Proteins: Structure, Function and Genetics

Volumn 28, Issue 1, 1997, Pages 53-58

  Kaltashov, Igor A ^a   Doroshenko, Vladimir M ^a   Cotter, Robert J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

hydrogen deuterium exchange; ion trap; ion molecule reactions; MALDI; peptide ions

Indexed keywords

AMMONIA; DEUTERIUM; GRAMICIDIN S; HYDROGEN; PEPTIDE; SODIUM;

ARTICLE; ENERGY TRANSFER; GAS; MASS SPECTROMETRY; PEPTIDE ANALYSIS; PRESSURE; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTON TRANSPORT; REACTION TIME;

CATIONS; CHEMISTRY, PHYSICAL; DEUTERIUM; GRAMICIDIN; HYDROGEN; MODELS, THEORETICAL; PEPTIDE FRAGMENTS; SODIUM; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0030901492     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(199705)28:1<53::AID-PROT5>3.0.CO;2-K     Document Type: Article

References (27)

1. Hunt, D.F., Sethi S.K. Gas phase ion/molecule isotope-exchange reactions:methodology for counting hydrogen atoms in specific organic structural environments by chemical ionization mass spectrometry. J. Am. Chem. Soc. 102: 6953-6963, 1980.
2. 2O. J. Am. Chem. Soc. 114:5897-5898, 1992.
3. 12+ ions produced by electrospray ionization mass spectrometry. J. Mass Spectrom. 31:247-254, 1996.
4. 12+ ions produced by electrospray ionization mass spectrometry. J. Mass Spectrom. 31:247-254, 1996.
5. 12+ ions produced by electrospray ionization mass spectrometry. J. Mass Spectrom. 31:247-254, 1996.
6. Nourse, B.D., Hettich, R.I., Buchanan, M.V. Methyl guanine isomer distinction by hydrogen/deuterium exchange using a Fourier transform mass spectrometer. J. Am. Soc. Mass Spectrom. 4:296-305, 1993.
7. Gur, E.H., De Koning, L.J., Nibbering, N.M.M. Gas-phase hydrogen-deuterium exchange of protonated alkylpeptides with (S)-and (R)-butan-2-ol. J. Mass Spectrom. 31:325-327, 1996.
8. 3. J. Am. Chem. Soc. 116:9765-9766, 1994.
9. 3. J. Am. Chem. Soc. 116:9765-9766, 1994.
10. Gross, D.S., Williams, E.R. Experimental measurement of Coulomb energy and intrinsic dielectric polarizability of a multiply protonated peptide ion using electrospray ionization Fourier-transform mass spectrometry. J. Am. Chem. Soc. 117:883-890, 1995.
11. Zhang, Z., Li, W., Guan, S., Marshall, A.G. Higher-order structure of gas-phase peptides from gas-phase H/D exchange experiments. Proc. ASMS Conf. Mass Spectrom. Allied Top. 44:1061, 1996.
12. Hemling, M.E., Conboy, J.J., Bean, M.F., Mentzer, M., Carr, S.A. Gas phase hydrogen/deuterium exchange in electrospray ionization mass spectrometry as a practical tool for structure elucidation. J. Am. Soc. Mass Spectrom. 5:434-442, 1994.
13. 3 in a tandem sector mass spectrometer. Int. J. Mass Spectrom. Ion Proc. 122: 109-119, 1992.
14. 3. J. Mass Spectrom. 30:666-674, 1996.
15. March, R.E. Ion trap mass spectrometry. Int. J. Mass Spectrom. Ion Proc. 118/119, 71-135, 1992; Cooks, R.G., Kaiser, R.E. Quadrupole ion trap mass spectrometry. Acc. Chem. Res. 23:213-219, 1990.
16. March, R.E. Ion trap mass spectrometry. Int. J. Mass Spectrom. Ion Proc. 118/119, 71-135, 1992; Cooks, R.G., Kaiser, R.E. Quadrupole ion trap mass spectrometry. Acc. Chem. Res. 23:213-219, 1990.
17. McLuckey, S.A., Habibi-Goudarzi, S. Decompositions of multiply charged oligonucleotide anions. J. Am. Chem. Soc. 115:12085-12086, 1993.
18. Doroshenko, V.M., Cotter, R.J. Advanced stored waveform inverse Fourier transform technique for a matrix-assisted laser desorption/ionization quadrupole ion trap mass spectrometer. Rapid Commun. Mass Spectrom. 10:65-73, 1996; Doroshenko, V.M., Cotter, R.J. Pulsed gas introduction for increasing peptide CID efficiency in a MALDI/quadrupole ion trap mass spectrometer. Anal. Chem. 68:463-472, 1996.
19. Doroshenko, V.M., Cotter, R.J. Advanced stored waveform inverse Fourier transform technique for a matrix-assisted laser desorption/ionization quadrupole ion trap mass spectrometer. Rapid Commun. Mass Spectrom. 10:65-73, 1996; Doroshenko, V.M., Cotter, R.J. Pulsed gas introduction for increasing peptide CID efficiency in a MALDI/quadrupole ion trap mass spectrometer. Anal. Chem. 68:463-472, 1996.
20. McLuckey, S.A., Van Berkel, G.J., Glish, G.L. Reactions of dimethylamine with multiply charged ions of cytochrome c. J. Am. Chem. Soc. 112:5668-5670, 1990; Habibi-Goudarzi, S., McLuckey, S.A. Ion trap collisional activation of the deprotonated deoxymononucleoside and deoxydinucleoside monophosphates. J. Am. Soc. Mass Spectrom. 6:102-113, 1996.
21. McLuckey, S.A., Van Berkel, G.J., Glish, G.L. Reactions of dimethylamine with multiply charged ions of cytochrome c. J. Am. Chem. Soc. 112:5668-5670, 1990; Habibi-Goudarzi, S., McLuckey, S.A. Ion trap collisional activation of the deprotonated deoxymononucleoside and deoxydinucleoside monophosphates. J. Am. Soc. Mass Spectrom. 6:102-113, 1996.
22. Herron, W.J., Goeringer, D.E., McLuckey, S.A. Gas-phase electron transfer reactions from multiply charged anions to rare gas cations. J. Am. Chem. Soc. 117:11555-11562, 1995; Herron, W.J., Goeringer, D.E., McLuckey, S.A. Reactions of polyatomic dianions with cations in the Paul trap. Rapid Commun. Spectrom. 10:277-281, 1996.
23. Herron, W.J., Goeringer, D.E., McLuckey, S.A. Gas-phase electron transfer reactions from multiply charged anions to rare gas cations. J. Am. Chem. Soc. 117:11555-11562, 1995; Herron, W.J., Goeringer, D.E., McLuckey, S.A. Reactions of polyatomic dianions with cations in the Paul trap. Rapid Commun. Spectrom. 10:277-281, 1996.
24. Ranasinghe, A., Cooks, R.G., Sethi, S.K. Selective isotopic exchange of polyfunctional ions in tandem mass spectrometry: Methodology, applications and mechanism. Org. Mass Spectrom. 27:77-83, 1992.
25. 6. Org. Mass Spectrom. 28:1119-1123, 1993.
26. Goeringer, D.E., McLuckey, S.A. Evolution of ion internal energy during collisional excitation in the Paul ion trap: A stochastic approach. J. Chem. Phys. 104:2214-2221, 1996.
27. Von Helden, G., Wyttenbach, T., Bowers, M.T. Inclusion of a MALDI ion source in the ion chromatography technique: Conformational information on polymer and biomolecular ions. Int. J. Mass Spectrom. Ion Proc. 146/147:349-364, 1995.