Site-directed mutagenesis of highly conserved amino acids in the first cytoplasmic loop of Drosophila Rh1 opsin blocks rhodopsin synthesis in the nascent state

EMBO Journal

Volumn 16, Issue 7, 1997, Pages 1600-1609

  Bentrop, J ^a   Schwab, K ^a   Pak, W L ^b   Paulsen, R ^a  

^a UNIVERSITY OF KARLSRUHE   (Germany)

^b PURDUE UNIVERSITY   (United States)

Author keywords

G protein coupled receptor; Photoreceptor; Protein processing; Retinal degeneration; Rhodopsin

Indexed keywords

AMINO ACID; ASPARAGINE; GLUTAMINE; ISOLEUCINE; LEUCINE; OPSIN; RHODOPSIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN GLYCOSYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ELECTRORETINOGRAPHY; EYE PROTEINS; GLYCOSYLATION; GTP-BINDING PROTEINS; HUMANS; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OPSIN; PHOTORECEPTORS, INVERTEBRATE; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, CELL SURFACE; RETINA; RHODOPSIN; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION, GENETIC;

EID: 0030901382     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.7.1600     Document Type: Article

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