Intravenous anti-D treatment of immune thrombocytopenic purpura: Experience in 272 patients

Blood

Volumn 89, Issue 8, 1997, Pages 2689-2700

  Scaradavou, Andromachi ^b   Woo, Bonnie ^b   Woloski, B M R ^b   Cunningham Rundles, Susanna ^b   Ettinger, Lawrence J ^b   Aledort, Louis M ^b   Bussel, James B ^a  

^a WEILL CORNELL MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

RHESUS D ANTIBODY; ZIDOVUDINE;

ADULT; ARTICLE; CHILD; CHILL; CHRONIC DISEASE; CLINICAL TRIAL; DOSE RESPONSE; DRUG MECHANISM; FEMALE; FEVER; HEADACHE; HEMATURIA; HEMOLYSIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IDIOPATHIC THROMBOCYTOPENIC PURPURA; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; NAUSEA; PRIORITY JOURNAL; SKIN DISCOLORATION; SPLENECTOMY; SUBCUTANEOUS DRUG ADMINISTRATION; VERTIGO; VOMITING;

EID: 0030900678     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.8.2689     Document Type: Article

References (58)

1. Harrington WJ, Ninnich V, Hollingsworth JW, Moore CB: Demonstration of thrombocytopenic factor in the blood of patients with thrombocytopenic purpura. J Lab Clin Med 38:1, 1951
2. Schulman NR, Leissinger CA, Hotchkiss AJ, Kautz CA: The nonspecific nature of platelet-associated IgG. Trans Assoc Am Physicians 95:213, 1982
3. Morris L, Distenfeld A, Amorosi E, Karpatkin S: Autoimmune thrombocytopenic purpura in homosexual men. Ann Intern Med 96:714, 1982
4. Karpatkin S: HIV-1 related thrombocytopenia. Hematol Oncol Clin North Am 4:193, 1990
5. Ballem P, Belzberg A, Devine D: HIV-related thrombocytopenia. N Engl J Med 328:1785, 1993
6. Sloand EM, Klein HG, Banks SM, Vareldzis B, Merritt S, Pierce P: Epidemiology of thrombocytopenia in HIV infection. Eur J Hematol 48:168, 1992
7. George NJ, Woolf SH, Raskob GE, Wasser JS, Aledort LM, Ballem PJ, Blanchette VS, Bussel JB, Cines DB, Kelton JG, Lichtin AE, McMillan R, Okerbloom JA, Regan DH, Warrier I: Idiopathic thrombocytopenic purpura: A practice guideline developed by explicit methods for The American Society of Hematology. Blood 88:3, 1996
8. Bithell TC: Thrombocytopenia caused by immunologic platelet destruction: Idiopathic thrombocytopenic purpura (ITP), drug-induced thrombocytopenia and miscellaneous forms, in Wintrobe's Clinical Hematology, vol 2. Philadelphia, PA, Lea and Febiger, 1993, p 1339
9. Walsh CM, Krigel R, Lennette ET, Karpatkin S: Thrombocytopenia in homosexual patients: Prognosis, response to therapy and prevalence of antibody to the retrovirus associated with the acquired immunodeficiency syndrome. Ann Intern Med 103:542, 1985
10. Abrams D, Kiprov D, Goedert J, Sarngadham M, Gallo R, Volberding P: Antibodies to HTLV III and developments of AIDS in homosexual men presenting with immune thrombocytopenia. Ann Intern Med 104:47, 1986
11. Fehr J, Hoffman V, Kappeler U: Transient reversal of thrombocytopenia in idiopathic thrombocytopenic purpura by high dose intravenous gammaglobulin. N Engl J Med 306:1254, 1982
12. Bussel JB, Pham LC: Intravenous treatment with gammaglobulin in adults with immune thrombocytopenic purpura: Review of the literature. Vox Sang 52:206, 1987
13. Bussel JB, Haimi JS: Isolated thrombocytopenia in patients infected with HIV: Treatment with intravenous gammaglobulin. Am J Hematol 28:79, 1988
14. Oksenhendler E, Bierling P, Chevret S, Delfraissy J-F, Laurian Y, Clauvel J-P, Seligmann M: Splenectomy is safe and effective in human immunodeficiency virus-related immune thrombocytopenia. Blood 82:29, 1993
15. Ballem PJ, Belzberg A, Devine DV, Eyster D, Spruston B, Chambers H, Doubroff P, Mikulash K: Kinetic studies of the mechanism of thrombocytopenia in patients with human immunodeficiency virus infection. N Engl J Med 327:1779, 1992
16. Hymes KB, Greene JB, Karpatkin S: The effect of azidothymidine on HIV-related thrombocytopenia. N Engl J Med 318:516, 1988
17. Clarkson SB, Bussel JB, Kimberly RP, Valinsky VE, Nachman RL, Unlekess JC: Treatment of refractory immune thrombocytopenic purpura with an anti-Fc gamma receptor antibody. N Engl J Med 314:1236, 1986
18. Salama A, Mueller-Eckhart C, Kiefel V: Effect of intravenous immunoglobulin in immune thrombocytopenia. Lancet 2:193, 1983
19. Salama A, Kiefel V, Amberg R, Mueller-Eckhart C: Treatment of autoimmune thrombocytopenic purpura with rhesus antibodies (anti-Rho(d)). Blut 49:29, 1984
20. Salama A, Kiefel V, Mueller-Eckhart C: Effect of IgG anti-Rho(D) in adult patients with chronic autoimmune thrombocytopenia. Am J Hematol 22:241, 1986
21. Panzer S, Grumayer ER, Hass OA, Niessner H, Graninger W: Efficacy of rhesus antibodies (anti-Rho(D)) in autoimmune thrombocytopenia: Correlation with response to high dose IgG and the degree of haemolysis. Blut 52:117, 1986
22. Becker T, Kuenzlen E, Salama A, Mertens R, Kiefel V, Weib H, Lampert G, Mueller-Eckhart C: Treatment of childhood idiopathic thrombocytopenic purpura with Rhesus antibodies (antiD). Eur J Pediatr 145:166, 1986.
23. Smith NA, Chakraverty RK, O'Beid D, Boughton BJ: Long-term response in a patient with idiopathic thrombocytopenic purpura following low dose anti D immunoglobulin treatment. Autoimmunity 4:115, 1989
24. Blanchette V, Imbach P, Andrew M, Adams M, McMillan J, Wang E, Milner R, Kiaser A, Barnard D, Bernstein M, Chan KW, Esseltine D, DeVeber B, Israels S, Kobrinsky N, Luke B: Randomized trial of intravenous immunoglobulin G, intravenous anti-D and oral prednisone in childhood acute immune thrombocytopenic purpura. Lancet 334:703, 1994
25. Andrew M, Blanchette VS, Adams M, Ali K, Barnard D, Chan KW, DeVeber LB, Esseltine D, Israels S, Kobrinsky N, Luke B, Milner RA, Woloski BMR, Vegh P: A multicenter study of the treatment of childhood chronic idiopathic thrombocytopenic purpura with anti-D. J Pediatr 120:522, 1992
26. Borgna-Pignatii C, Battisti L, Zecca M, Locatelli F: Treatment of chronic childhood immune thrombocytopenic purpura with intramuscular anti-D immunoglobulins. Br J Haematol 88:618, 1994
27. Boughton BJ, Chakraverty R, Baglin TP, Simpson A, Galvin G, Rose P, Rohlova B: The treatment of chronic idiopathic thrombocytopenia with anti-D (Rho) immunoglobulin: Its effectiveness, safety and mechanism of action. Clin Lab Haematol 10:275, 1988
28. Smith NA, Chakraverty Rk, Boughton BJ: The successful treatment of idiopathic thrombocytopenic purpura with low dose non specific IgG component of anti-D immunoglobulin. Clin Lab Haematol 12:131, 1990
29. Bussel JB, Graziano JN, Kimberly RP, Pahwa S, Aledort LM: Intravenous anti-D treatment of immune thrombocytopenic purpura: Analysis of efficacy, toxicity and mechanism of effect. Blood 77:1884, 1991
30. Gringeri A, Cattaneo M, Santagostino E, Mannucci PM: Intramuscular anti-D immunoglobulins for home treatment of chronic immune thrombocytopenic purpura. Br J Haematol 80:337, 1992
31. Rodeghiero F, Schiavotto C, Castaman G, Vespignani M, Ruggeri M, Dini E: A follow-up study of 49 adult patients with idiopathic thrombocytopenic purpura treated with high-dose immunoglobulins and anti-D immunoglobulins. Haematologica 77:248, 1992
32. Rossi E, Vimercati R, Damasio E, Terranage A, Giovanni M, Anselmo M, Dodi F, del bono V, Pagano G, Gualandi F, Queirold MA, Pizzaferri R, Marmont A: Treatment of idiopathic thrombocytopenic purpura in HIV-positive patients with rhesus antibodies (anti D). Haematologica 72:529, 1987
33. Oksenhendler E, Bierling P, Brossard Y, Schenmetzler C, Girard P-M, Seligmann M, Clauval J-P: Anti-RH immunoglobulin therapy for human immunodeficiency virus-related immune thrombocytopenic purpura. Blood 71:1499, 1988
34. Bussel JB, Graziano JN, Kimberly RP, Pahwa S, Aledort LM: Anti-D Ig for treatment of immune thrombocytopenic purpura. Blood 78:2157, 1991 (letter).
35. Baglin TP, Smith MP, Boughton BJ: Anti-Rh(D) immunoglobulin for immune thrombocytopenic purpura. Lancet 2:49, 1986
36. Cardo LJ, Strack M, Williams J: Anti-D for the treatment of splenectomized patients with immune thrombocytopenic purpura. Blood 78:2786, 1991 (letter)
37. Bowman JM, Chown B, Pollock J: Low protein Rh immune globulin (Rh IgG)-purity, stability activity and prophylactic value. Vox Sang 24:301, 1973
38. Bowman JM, Friesen AD, Pollock IM, Taylor WE: WinRho: Rh immune globulin prepared by ion exchange for intravenous use. Can Med Assoc J 123:1121, 1980
39. Rho (D) Immune Globulin Intravenous (Human), package insert. Cangene Corp, Winnipeg, Manitoba, Canada, and NABI, Boca Raton, FL.
40. Rigaud M, Leibovitz E, Sin Quee C, Kaul A, Nardi M, Pollack H, Lawrence R, Dijohn D, Krasinski K, Karpatkin M, Borkowsky W: Thrombocytopenia in children infected with human immunodeficiency virus: Long-term follow-up and therapeutic considerations. J AIDS 5:450, 1992
41. Imbach P, d'Apuzzo V, Hirt A, Rossi E, Vest M, Barandun S, Baumgartner C, Morell A, Schoni M, Wagner HP: High-dose intravenous gammaglobulin for idiopathic thrombocytopenic purpura in childhood. Lancet 1:1228, 1981
42. Beardsley DS: Platelet abnormalities in infancy and childhood, in Nathan DG, Oski FA (eds): Hematology of Infancy and Childhood, vol 2. Philadelphia, PA, Saunders, 1994, p 1561
43. Cortelazzo S, Finazzi G, Buelli M, Molteni A, Viero P, Barbui T: High risk of severe bleeding in aged patients with chronic idiopathic thrombocytopenic purpura. Blood 77:31, 1991
44. Hilgartner MW, Buckley JD, Operskalski EA, Pike MC, Mosley JW: Purity of factor VIII concentrates and serial CD4 counts. Lancet 341:1373, 1993
45. deBiasi R, Rocino A, Miraglia E, Mastrullo L, Quirino AA: The impact of very high purity factor VIII concentrate on the immune system of human immunodeficiency virus-infected hemophiliacs: A randomized, prospective two-year comparison with an intermediate purity concentrate. Blood 78:1919, 1991
46. Fletcher MA, Mosley JW, Hassett J, Gjerset GF, Kaplan J, Parker JW, Donegan E, Lusher JM, Lee H, and the Transfusion Safety Study Group: Effect of age on human immunodeficiency virus type 1-induced changes in lymphocyte populations among persons with congenital clotting disorders. Blood 80:831, 1992
47. Ho DD: Viral counts count in HIV infection. Science 272:1124, 1996
48. Saag MS, Holodniy M, Kuritzkes DR, O'Brien WA, Coombs R, Poscher ME, Jacobsen DM, Shaw GM, Richman DD, Volberding PA: HIV viral load markers in clinical practice. Nat Med 2:635, 1996
49. Zucker-Franklin D, Cao YZ: Megakaryocytes of human immunodeficiency virus-infected individuals express viral RNA. Proc Natl Acad Sci USA 86:5595, 1989
50. Zucker-Franklin D, Termin CS, Cooper MC: Structural changes in the megakaryocytes of patients infected with the human immunodeficiency virus (HIV-1). Am J Pathol 134:1295, 1989
51. Ballem PJ, Segal GM, Stratton JR, Gernsheimer T, Adamson JW, Slichter SJ: Mechanisms of thrombocytopenia in chronic autoimmune thrombocytopenic purpura: Evidence of both impaired platelet production and increased platelet clearance. J Clin Invest 80:33, 1987
52. Boros P, Gardos E, Bekesi GJ, Unkeless JC: Change in expression of FcγRIII (CD16) on neutrophils from human immunodeficiency virus-infected individuals. Clin Immunol Immunopathol 54:281, 1990
53. Bender BS, Quinn TC, Spivak JL: Homosexual men with thrombocytopenia have impaired reticuloendothelial system Fc receptor-specific clearance. Blood 70:392, 1987
54. Mollison PL: Red cell incompatibility in vivo, in Wintrobe, Mollison (eds): Blood Transfusion in Clinical Medicine (ed 7). New York, NY, Blackwell, 1983, p 558
55. Godeau B, Oksenhendler E, Brossard Y, Bartoleyns J, Leaute J-B, Duedari N, Schaeffer A, Bierling P: Treatment of chronic autoimmune thrombocytopenic purpura with monoclonal anti-D. Transfusion 36:328, 1996
56. Rho (D) immune globulin IV for prevention of Rh isoimmunization and for treatment of ITP. Med Lett 38:6, 1996
57. Horowitz B, Bonomo R, Prince AM, Chin SN, Brotman B, Shulman RW: Solvent/detergent-treated plasma: A virus-inactivated substitute for fresh frozen plasma. Blood 79:826, 1992
58. Gabra GS, Mitchell R: Anti-D immunoglobulin and immune thrombocytopenia - A problem of ethics in blood transfusion practice. Vox Sang 54:246, 1988