Calcium-enriched foods and bone mass growth in prepubertal girls: A randomized, double-blind, placebo-controlled trial

Journal of Clinical Investigation

Volumn 99, Issue 6, 1997, Pages 1287-1294

  Bonjour, Jean Philippe ^a,d   Carrie, Anne Lise ^c   Ferrari, Serge ^a   Clavien, Helene ^a   Slosman, Daniel ^b   Theintz, Gerald ^b   Rizzoli, Rene ^a  

^a WORLD HEALTH ORGANIZATION   (Switzerland)

^b UNIVERSITY HOSPITAL   (Switzerland)

^c NESTLÉ RESEARCH CENTER   (Switzerland)

^d Faculty of Medicine   (Switzerland)

Author keywords

bone growth; bone mineral density; calcium intake; calcium enriched foods; statural height

Indexed keywords

PLACEBO;

ARTICLE; BODY HEIGHT; BONE DENSITY; BONE GROWTH; BONE MASS; BONE MINERAL; CALCIUM INTAKE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR; HUMAN; LUMBAR SPINE; PREPUBERTY; PRIORITY JOURNAL; RADIUS; RANDOMIZED CONTROLLED TRIAL;

EID: 0030900599     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119287     Document Type: Article

References (47)

1. Riggs, B.L., and L.J. Melton III. 1988. Osteoporosis. Etiology, Diagnosis, and Management. Raven Press, New York.
2. Hui, S.L., C.W. Slemenda, and C.C. Johnston, Jr. 1990. The contribution of bone loss to postmenopausal osteoporosis. Osteoporosis Int. 1:30-34.
3. Johnston, C.C., Jr., and C. Longcope. 1990. Premenopausal bone loss - a risk factor for osteoporosis. N. Engl. J. Med. 323:1271-1272.
4. Nordin, B.E.C. 1976. Calcium, phosphate, and magnesium metabolism. Clinical Physiology and Diagnostic Procedures. Churchill Livingstone, Edinburgh, London, and New York.
5. Hui, S.L., C.C. Johnston, Jr., and R.B. Mazess. 1985. Bone mass in normal children and young adults. Growth. 49:34-43.
6. Pollitzer, W.S., and J.J.B. Anderson. 1989. Ethnic and genetic differences in bone mass: a review with a hereditary vs. environmental perspective. Am. J. Clin. Nutr. 50:1244-1259.
7. Ott, S.M. 1990. Attainment of peak bone mass. J. Clin. Endocrinol. Metab. 71:1082A-1082C.
8. Bonjour, J.P., G. Theintz, B. Buchs, D. Slosman, and R. Rizzoli. 1991. Critical years and stages of puberty for spinal and femoral bone mass accumulation during adolescence. J. Clin. Endocrinol. & Metab. 73:555-563.
9. Pocock, N.A., J.A. Eisman, J.L. Hopper, M.G. Yeates, P.N. Sambrook, and S. Eberl. 1987. Genetic determinants of bone mass in adults - a twin study. J. Clin. Invest. 80:706-710.
10. Seeman, E., J.L. Hopper, L.A. Bach, M.E. Cooper, E. Parkinson, J. McKay, and G. Jerums. 1989. Reduced bone mass in daughters of women with osteoporosis. N. Engl. J. Med. 320:554-558.
11. Tylavsky, F.A., A.D. Bortz, R.L. Hancock, and J.J.B. Anderson. 1989. Familial resemblance of radial bone mass between premenopausal mothers and their college-age daughters. Calcif. Tissue Int. 45:265-272.
12. Matkovic, V., D. Fontana, C. Tominac, P. Goel, and C.H. Chesnut III. 1990. Factors that influence peak bone mass formation: A study of calcium balance and the inheritance of bone mass in adolescent females. Am. J. Clin. Nutr. 52:878-888.
13. Lutz, J., and R. Tesar. 1990. Mother-daughter pairs: spinal and femoral bone densities and dietary intakes. Am. J. Clin. Nutr: 52:872-877.
14. Bachrach, L.K., P.A. Guido, D. Katzman, I.F. Litt, and R. Marcus. 1990. Decreased bone density in adolescent girls with anorexia nervosa. Pediatrics. 86:440-447.
15. Bell, N.H., J. Shary, J. Stevens, M. Garza, L. Gordon, and J. Edwards. 1991. Demonstration that bone mass is greater in black than in white children. J. Bone Miner. Res. 6:719-723.
16. Sandler, R.B., C.W. Slemenda, R.E. LaPorte, J.A. Cauley, M.M. Schramm, M.L. Barresi, and A.M. Kriska. 1985. Postmenopausal bone density and milk consumption in childhood and adolescence. Am. J. Clin. Nutr. 42:270-274.
17. Chan, G. 1991. Dietary calcium and bone mineral status of children and adolescents. Am. J. Dis. Child. 145:631-634.
18. Sentipal, J.M., G.M. Wardlaw, J. Mahan, and V. Matkovic. 1991. Influence of calcium intake and growth indexes on vertebral bone mineral density in young females. Am. J. Clin. Nutr. 54:425-428.
19. Tylavsky, F.A., J.J.B. Anderson, R.V. Talmage, and T.N. Taft. 1992. Are calcium intakes and physical activity patterns during adolescence related to radial bone mass of white college-age females? Osteoporosis Int. 2:232-240.
20. Lloyd, T., N. Rollings, M.B. Andon, L.M. Demers, D.F. Eggli, K. Kiselhorst, H. Kulin, J.R. Landis, J.K. Martel, G. Orr, and P. Smith. 1992. Determinants of bone density in young women. I. Relationships among pubertal development, total body bone mass, and total body bone density in premenarchal females. J. Clin. Endocrinol. & Metab. 75:383-387.
21. Ruiz, J.C., C. Mandel, and M. Garabedian. 1995. Influence of spontaneous calcium intake and physical exercise on the vertebral and femoral bone mineral density of children and adolescents. J. Bone Miner. Res. 10:675-682.
22. Kalzman, D.K., L.K. Bachrach, D.R. Carter, and R. Marcus. 1991. Clinical and anthropometric correlates of bone mineral acquisition in healthy adolescent girls. J. Clin. Endocrinol. Metab. 73:1332-1339.
23. Kröger, H., A. Kotaniemi, P. Vainio, and E. Alhava. 1992. Bone densitometry of the Spine and Femur in Children by Dual-Energy X-ray Absorptiometry. Bone Miner. 17:75-85.
24. Grimston, S.K., K. Morrison, J.A. Harder, and D.A. Hanley. 1992. Bone mineral density during puberty in Western Canadian children. Bone Miner. 19: 85-96.
25. Kröger, H., A. Kotaniemi, L. Kröger, and E. Alhava. 1993. Development of bone mass and bone density of the spine and femoral neck - a prospective study of 65 children and adolescents. Bone Miner. 23:171-182.
26. Young, D., J.L. Hopper, C.A. Nowson, R.M. Green, A.J. Sherwin, B. Kaymakci, M. Smid, C.S. Guest, R.G. Larkins, and J.D. Wark. 1995. Determinants of bone mass in 10- to 26-year-old females: A twin study. J. Bone Miner. Res. 10:558-567.
27. Carrié, A. L., and J. P. Bonjour. 1995. Osteoporosis as a pediatric problem. Pediatr. Clin. North Am. 42:811-824.
28. Johnston, C.C., J.Z. Miller, C.W. Slemenda, T.K. Reister, S. Hui, J.C. Christian, and M. Peacock. 1992. Calcium supplementation and increases in bone mineral density in children. N. Engl. J. Med. 327:82-87.
29. Lloyd, T., M.B. Andon, N. Rollings, J.K. Martel, J.R. Landis, L.M. Demers, D.F. Eggli, K. Kieselhorst, and H.E. Kulin. 1993. Calcium supplementation and bone mineral density in adolescent girls. JAMA. 270:841-844.
30. Lee, W.T.K., S.S.F. Leung, S.H. Wang, Y.C. Xu, W.P. Zeng, J. Lau, S.J. Oppenheimer, and J.C.Y. Cheng. 1994. Double-blind, controlled calcium supplementation and bone mineral accretion in children accustomed to a low-calcium diet. Am. J. Clin. Nutr. 60:744-750.
31. Dawson-Hughes, B., G. E. Dallal, E. A. Krall, L. Sadowski, N. Sahyoun, and S. Tannenbaum. 1990. A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women. N. Engl. J. Med. 323: 878-883.
32. Theintz, G., B. Buchs, R. Rizzoli, D. Slosman, H. Clavien, P.C. Sizonenko, and J.P. Bonjour. 1992. Longitudinal monitoring of bone mass accumulation in healthy adolescents: Evidence for a marked reduction after 16 years of age at the levels of lumbar spine and femoral neck in female subjects. J. Clin. Endocrinol. Metab. 75:1060-1065.
33. Katzman D.K., L.K. Bachrach, D.R. Carter, and R. Marcus. 1991. Clinical and anthropometric correlates of bone mineral acquisition in healthy adolescent girls. J. Clin. Endocrinol. Metab. 73:1332-1339.
34. Carter D.R., M.L. Bouxsein, and R. Marcus. 1992. New approaches for interpreting projected bone densitometric data. J. Bone Miner. Res. 7:137-145.
35. National Institutes of Health. 1994. Optimal calcium intake. NIH Consensus statement 12:1-31.
36. Gilsanz, V., T.F. Roe, J. Antunez, M. Carlson, M.L. Duarte, and W.G. Goodman. 1991. Effect of dietary calcium on bone density in growing rabbits. Am. J. Physiol. 260:471-476.
37. Holbrook T.L., E. Barrett-Connor, D.L. Wingard. 1988. Dietary calcium and risk of hip fracture: 14-year prospective population study. Lancet. ii: 1046-1049.
38. Matkovic V., D. Fontana, C. Tominac, P. Goel, C.H. Chesnut. 1990. Factors that influence peak bone mass: a study of calcium balance and the inheritance of bone mass in adolescent females. Am. J. Clin. Nutr. 52:878-888.
39. Matkovic, V., and R. P. Heaney. 1992. Calcium balance during human growth: evidence for threshold behavior. Am. J. Clin. Nutr. 55:992-996.
40. Forbes, R.M., K.E. Weingartner, H.M. Parker, R.M. Bell, and J.W. Erdman, Jr. 1979. Bioavailability to rats of zinc, magnesium and calcium in casein-, egg- and soy protein-containing diets. J. Nutr. 109:1652-1660.
41. Dawson-Hughes, B. 1991. Calcium supplementation and bone loss: a review of controlled clinical trials. Am. J. Clin. Nutr. 54:(suppl.)274-280.
42. Parfitt, A.M. 1994. The two faces of growth: Benefits and risks to bone integrity. Osteoporosis Int. 4:382-398.
43. Heaney, R.P. 1993. Nutritional factors in osteoporosis. Annu. Rev. Nutr. 13:287-316.
44. Kanis, J.A. 1994. Calcium nutrition and its implications for osteoporosis. Part I. Children and healthy adults. Eur. J. Clin. Nutr. 48:757-767.
45. Kanis, J.A. 1994. Calcium nutrition and its implications for osteoporosis. Part II. After menopause. Eur. J. Clin. Nutr. 48:833-841.
46. Chevalley, T., R. Rizzoli, V. Nydegger, D. Slosman, C.H. Rapin, J.P. Michel, H. Vasey, and J.P. Bonjour. 1994. Effects of calcium supplements on femoral bone mineral density and vertebral fracture rate in vitamin-D-replete elderly patients. Osteoporosis Int. 4:245-252.
47. Clavien H., G. Theintz, R. Rizzoli, and J.-P. Bonjour. 1996. Does puberty alter dietary habits in adolescents livins in a western society? J. Adolesc. Health. 19:68-75.