Blockade of protein kinase C is involved in the inhibition by cycloheterophyllin of neutrophil superoxide anion generation

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 355, Issue 5, 1997, Pages 551-558

  Wang, J P ^a   Raung, S L ^a   Tsao, L T ^a   Hsu, M F ^b   Lin, C N ^c  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cycloheterophyllin; Inositol trisphosphate; Intracellular Ca2+ concentration; NADPH oxidase; Neutrophil (rat); Protein kinase C; Superoxide anion

Indexed keywords

CALCIUM; FLAVONE DERIVATIVE; INOSITOL TRISPHOSPHATE; PROTEIN KINASE C; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STAUROSPORINE; SUPEROXIDE;

ANIMAL CELL; ARTICLE; BRAIN; CONTROLLED STUDY; ENZYME INHIBITION; NEUTROPHIL; NONHUMAN; RAT;

ANIMALS; ARACHIDONIC ACID; CARCINOGENS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLAVONOIDS; INOSITOL 1,4,5-TRISPHOSPHATE; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NADPH OXIDASE; NEUTROPHIL ACTIVATION; NEUTROPHILS; PHORBOL 12,13-DIBUTYRATE; PROTEIN KINASE C; RATS; STAUROSPORINE; SUPEROXIDES; TETRADECANOYLPHORBOL ACETATE;

EID: 0030899931     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00004982     Document Type: Article

References (40)

1. Badwey JA, Karnovsky ML (1980) Active oxygen species and the functions of phagocytic leukocytes. Annu Rev Biochem 49:695-726
2. Baehner R L, Murrmann SK, Davis J, Johnston RB Jr (1975) The role of superoxide anion and hydrogen peroxide in phagocytosis-associated oxidative metabolic reactions. J Clin Invest 56:571-576
3. Bellavite P, Corso F, Dusi S, Grzeskowiak M, Della Bianca V, Rossi F (1988) Activation of NADPH-dependent superoxide production in plasma membrane extracts of pig neutrophils by phosphatidic acid. J Biol Chem 263:8210-8214
4. Bellavite P, Serra MC, Davoli A, Bannister JV, Rossi F (1983) The NADPH oxidase of guinea pig polymorphonuclear leukocytes. Properties of the deoxycholate extracted enzyme. Mol Cell Biochem 52:17-25
5. Castagna M, Takai Y, Kaibuchi K, Sano K, Kikkawa U, Nishizuka Y (1982) Direct activation of calcium activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J Biol Chem 257:7847-7851
6. Cox JA, Jeng AY. Blumberg PM, Tauber AI (1987) Comparison of subcellular activation of the human neutrophil NADPH-oxidase by arachidonic acid, sodium dodecyl sulfate (SDS), and phorbol myristate acetate (PMA). J Immunol 138:1884-1888
7. 2+ concentration. Biochem J 229:361-367
8. Downes CP, Michell RH (1981) The polyphosphoinositide phosphodiesterase of erythrocyte membranes. Biochem J 198:133-140
9. Go M, Koumoto J, Kikkawa U, Nishizuka Y (1987) Protein kinase C purification by high-performance liquid chromatography: an improved method. Methods Enzymol 141:424-428
10. Goldberg B, Stern A (1977) The role of the superoxide anion as a toxic species in the erythrocyte. Arch Biochem Biophys 178:218-225
11. 2+ indicator with greatly improved fluorescence properties. J Biol Chem 260:3440-3450
12. Halliwell B, Gutteridge JM (1990) Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol 186:1-85
13. Hannun YA, Loomis CR, Merrill AH Jr, Bell RM (1986) Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. J Biol Chem 261:12604-12609
14. Hano Y, Aida M, Shiina M, Nomura T, Kawai T, Ohe H, Kagei K (1989) Artonins A and B, two new prenylflavones from the root bark of Artocarpus heterophyllus LAMK. Heterocycles 29:1447-1453
15. Inoue M, Kishimoto A, Takai Y, Nishizuka Y (1977) Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain. J Biol Chem 252:7610-7616
16. Jin W, Lo TM. Loh HH, Thayer SA (1994) U73122 inhibits phospholipase C-dependent calcium mobilization in neuronal cells. Brain Res 642:237-243
17. Kase H, Iwahashi K, Nakanishi S, Matsuda Y, Yamada K, Takahashi M, Murakata C, Sato A, Kaneko M (1987) K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem Biophys Res Commun 142:436-440
18. Kramer IM, Verhoeven AJ, Van Der Bend RL, Weening RS, Roos D (1988) Purified protein kinase C phosphorylates a 47-kDa protein in control neutrophil cytoplasts but not in neutrophil cytoplasts from patients with the autosomal form of chronic granulomatous disease. J Biol Chem 263:2352-2357
19. 2+-handling by non-muscle cells: studies in human neutrophils and HL-60 cells. Cell Calcium 10:351-361
20. Lee MH, Bell RM (1986) The lipid binding, regulatory domain of protein kinase C. A 32-kDa fragment contains the calcium- and phosphatidylserine-dependent phorbol diester binding activity. J Biol Chem 261:14867-14870
21. Lehmeyer JE, Snyderman R, Johnston RB Jr (1979) Stimulation of neutrophil oxidativc metabolism by chemotactic peptides: influence of calcium ion concentration and cytochalasin B and comparison with stimulation by phorbol myristate acetate. Blood 54:35-45
22. Lin CN, Lu CM, Huang PL (1995) Flavonoids from Artocarpus heterophyllus. Phytochemistry 39:1447-1451
23. Majumdar S, Rossi MW, Fujiki T, Phillips WA, Disa S, Queen CF, Johnston RB Jr, Rosen OM, Corkey BE, Korchak HM (1991) Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent β-protein kinase C and a novel calcium-independent, phospholipid-dependent protein kinase which is inhibited by long chain fatty acyl coenzyme A. J Biol Chem 266:9285-9294
24. Matsumoto H, Sasaki Y (1989) Staurosporine. a protein kinase C inhibitor interferes with proliferation of arterial smooth muscle cells. Biochem Biophys Res Commun 158:105-109
25. 2+ influx following receptor activation. Trends Pharmacol Sci 12:289-292
26. Newton AC (1995) Protein kinase C: structure, function, and regulation. J Biol Chem 270:28495-28498
27. Nishizuka Y (1986) Studies and perspectives of protein kinase C. Science 233:305-312
28. 2+ mobilization in guinea pig neutrophils. J Biol Chem 260:15771-15780
29. Reddy GR, Ueda N, Hada T, Sackeyfio AC, Yamamoto S, Hano Y, Aida M, Nomura T (1991) A prenylflavone, artonin E, as arachidonate 5-lipoxygenase inhibitor. Biochem Pharmacol 41:115-118
30. Robinson JM, Badwey JA, Karnovsky ML, Karnovsky MJ (1984) Superoxide release by neutrophils: synergistic effects of a phorbol ester and a calcium ionophore. Biochem Biophys Res Commun 122:734-739
31. Roskoski R Jr (1983) Assays of protein kinase. Methods Enzymol 99:3-6
32. ++orming NADPH oxidase of the phagocytes: nature, mechanisms of action and function. Biochem Biophys Acta 853:65-89
33. Segal AW, Abo A (1993) The biochemical basis of the NADPH oxidase of phagocytes. Trends Biochem Sci 18:43-47
34. Smith RJ, Sam LM, Justen JM, Bundy GL, Bala GA, Bleasdale JE (1990) Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness. J Pharmacol Exp Ther 253:688- 697
35. Tallarida RJ, Murray RB (1987) Analysis of the regression line. In: Tallarida RJ, Murray RB (eds) Manual of pharmacological calculations with computer programs. Springer, Berlin Heidelberg New York, pp 16-18
36. ++ dependent protein kinase. Biochem Biophys Res Commun 135:397-402
37. Tanaka Y, Miyake R, Kikkawa U, Nishizuka Y (1986) Rapid assay of binding of tumor-promoting phorbol esters to protein kinase C. J Biochem 99:257-261
38. Wang JP, Raung SL, Hsu MF, Chen CC (1994) Inhibition by gomisin C (a lignan from Schizandra chinensis) of the respiratory burst of rat neutrophils. Br J Pharmacol 113:945-953
39. Wang JP, Raung SL, Kuo YH, Teng CM (1995) Daphnoretin-indced respiratory burst in rat neutrophils is, probably, mainly through protein kinase C activation. Eur J Pharmacol 288:341-348
40. Wolfson M, McPhail LC, Nasrallah VN, Snyderman R (1985) Phorbol myristate acetate mediates redistribution of protein kinase C in human neutrophils: potential role in the activation of the respiratory burst enzyme. J Immunol 135:2057-2062