Functional dissection of the B'' component of RNA polymerase III transcription factor IIIB: A scaffolding protein with multiple roles in assembly and initiation of transcription

Molecular and Cellular Biology

Volumn 17, Issue 4, 1997, Pages 1868-1880

  Kumar, Ashok ^a   Kassavetis, George A ^a   Geiduschek, E Peter ^a   Hambalko, Monica ^a   Brent, Cynthia J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA DIRECTED RNA POLYMERASE III; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; COMPLEX FORMATION; DNA BINDING; DNA PROTEIN COMPLEX; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION;

SACCHAROMYCES CEREVISIAE;

EID: 0030899809     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.4.1868     Document Type: Article

References (54)

1. Aasland, R., A. F. Stewart, and T. Gibson. 1996. The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB. Trends Biochem. Sci. 21: 87-88.
2. Archambault, J., C. A. Milne, K. T. Schappert, B. Braum, J. D. Friesen, and J. Segall. 1992. The deduced sequence of the transcription factor TFIIIA from Saccharomyces cerevisiae reveals extensive divergence from Xenopus TFIIIA. J. Biol. Chem. 267:3282-3288.
3. Bartholomew, B., G. A. Kassavetis, and E. P. Geiduschek. 1991. Two components of Saccharomyces cerevisiae TFIIIB are stereospecifically located upstream of a tRNA gene and interact with the second largest subunit of TFIIIC. Mol. Cell. Biol. 11:5181-5189.
4. Bartholomew, B., G. A. Kassavetis, B. R. Braun, and E. P. Geiduschek. 1990. The subunit structure of Saccharomyces cerevisiae transcription factor IIIC probed with a novel photocrosslinking reagent. EMBO J. 9:2197-2205.
5. Braun, B. R., B. Bartholomew, G. A. Kassavetis, and E. P. Geiduschek. 1992. Topography of transcription factor complexes on the Saccharomyces cerevisiae 5S RNA gene. J. Mol. Biol. 228:1063-1077.
6. Braun, B. R., G. A. Kassavetis, and E. P. Geiduschek. 1992. Bending of the Saccharomyces cerevisiae 5S rRNA gene in transcription factor complexes. J. Biol. Chem. 267:22562-22569.
7. Braun, B. R., D. L. Riggs, G. A. Kassavetis, and E. P. Geiduschek. 1989. Multiple states of protein-DNA interaction in the assembly of transcription complexes on Saccharomyces cerevisiae 5S ribosomal RNA genes. Proc. Natl. Acad. Sci. USA 86:2530-2534.
8. Brow, D. A., and C. Guthrie. 1990. Transcription of a yeast U6 snRNA gene requires a polymerase III promoter element in a novel position. Genes Dev. 4:1345-1356.
9. Buratowski, S., and H. Zhou. 1992. A suppressor of TBP mutations encodes an RNA polymerase III transcription factor with homology with TFIIB. Cell 71:221-210.
10. Burnol, A.-F., F. Margottin, P. Schultz, M.-C. Marsolier, P. Oudet, and A. Sentenac. 1993. Basal promoter and enhancer element of yeast U6 snRNA gene. J. Mol. Biol. 233:644-658.
11. Chaussivert, N., C. Conesa, S. Shaaban, and A. Sentenac. 1995. Complex interactions between yeast TFIIIB and TFIIIC. J. Biol. Chem. 270:15353-15358.
12. Colbert, T., and S. Hahn. 1992. A yeast TFIIB-related factor involved in RNA polymerase III transcription. Genes Dev. 6:1940-1949.
13. Eschenlauer, J. B., M. W. Kaiser, V. L. Gerlach, and D. A. Brow. 1993. Architecture of a yeast U6 RNA gene promoter. Mol. Cell. Biol. 13:3015-3026.
14. Geiduschek, E. P., and G. A. Kassavetis. 1995. Comparing transcriptional initiation by RNA polymerases I and III. Curr. Opin. Cell Biol. 7:344-351.
15. Greiner, D. P., K. A. Hughes, A. H. Gunasekera, and C. F. Meares. 1996. Binding of the sigma 70 protein to the core subunits of Escherichia coli RNA polymerase, studied by iron-EDTA protein footprinting. Proc. Natl. Acad. Sci. USA 93:71-75.
16. Hahn, S., S. Buratowski, P. A. Sharp, and L. Guarente. 1989. Isolation of the gene encoding the yeast TATA binding protein TFIID: a gene identical to the SPT15 suppressor of Ty element insertions. Cell 58:1173-1181.
17. Hernandez, N. 1993. TBP, a universal eukaryotic transcription factor? Genes Dev. 7:1291-1308.
18. Heyduk, E., and T. Heyduk. 1994. Mapping protein domains involved in macromolecular interactions: a novel protein footprinting approach. Biochemistry 33:9643-9650.
19. Heyduk, T., E. Heyduk, K. Severinov, H. Tang, and R. H. Ebright. 1996. Determinants of RNA polymerase α subunit for interaction with β,β′, and σ subunits: hydroxyl-radical protein footprinting. Proc. Natl. Acad. Sci. USA 93:10162-10166.
20. Huet, J., C. Conesa, N. Manaud, N. Chaussivert, and A. Sentenac. 1994. Interactions between yeast TFIIIB components. Nucleic Acids Res. 22:3433-3439.
21. Huet, J., and A. Sentenac. 1992. The TATA-binding protein participates in TFIIIB assembly on tRNA genes. Nucleic Acids Res. 20:6451-6454.
22. Joazeiro, C. A., G. A. Kassavetis, and E. P. Geiduschek. 1994. Identical components of yeast transcription factor IIIB are required and sufficient for transcription of TATA box-containing and TATA-less genes. Mol. Cell. Biol. 14:2798-2808.
23. Joazeiro, C. A. P., G. A. Kassavetis, and E. P. Geiduschek. 1996. Alternative outcomes in assembly of promoter complexes: the roles of TBP and a flexible linker in placing TFIIIB on tRNA genes. Genes Dev. 10:725-739.
24. Kassavetis, G. A., S. T. Nguyen, R. Kobayashi, A. Kumar, E. P. Geiduschek, and M. Pisano. 1995. Cloning, expression and function of TFC5, the gene encoding the B″ component of the Saccharomyces cerevisiae RNA polymerase III transcription factor TFIIIB. Proc. Natl. Acad. Sci. USA 92:9786-9790.
25. Kassavetis, G. A., C. A. P. Joazeiro, M. Pisano, E. P. Geiduschek, T. Colbert, S. Hahn, and J. A. Blanco. 1992. The role of the TATA binding protein in the assembly and function of the multisubunit yeast RNA polymerase III transcription factor, TFIIIB. Cell 71:1055-1064.
26. Kassavetis, G. A., B. Bartholomew, J. A. Blanco, T. E. Johnson, and E. P. Geiduschek. 1991. Two essential components of the Saccharomyces cerevisiae transcription factor IIIB: transcription and DNA-binding properties. Proc. Natl. Acad. Sci. USA 88:7308-7312.
27. Kassavetis, G. A., B. R. Braun, L. H. Nguyen, and E. P. Geiduschek. 1990. S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III while TFIIIA and TFIIIC are assembly factors. Cell 60:235-245.
28. Kassavetis, G. A., M. Hambalko, and S. Nguyen. Unpublished data.
29. Kassavetis, G. A., D. L. Riggs, R. Negri, L. H. Nguyen, and E. P. Geiduschek. 1989. Transcription factor IIIB generates extended DNA interactions in RNA polymerase III transcription complexes on tRNA genes. Mol. Cell. Biol. 9:2551-2566.
30. Khoo, B., B. Brophy, and S. P. Jackson. 1994. Conserved functional domains of the RNA polymerase III general transcription factor BRF. Genes Dev. 8:2879-2890.
31. Kim, J. L., D. B. Nikolov, and S. K. Burley. 1993. Co-crystal structure of TBP recognizing the minor groove of a TATA element. Nature 365:520-527.
32. Kim, Y., J. H. Geiger, S. Hahn, and P. Sigler. 1993. Crystal structure of a yeast TBP/TATA box complex. Nature 365:512-520.
33. Kumar, A. Unpublished data.
34. Kunkel, T. A., J. D. Roberts, and R. A. Zakour. 1987. Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol., 154:367-382.
35. Lefèbvre, O., C. Carles, C. Conesa, R. N. Swanson, F. Bouet, M. Riva, and A. Sentenac. 1992. TFC3: gene encoding the B-block binding subunit of the yeast transcription factor IIIC. Proc. Natl. Acad. Sci. USA 89:10512-10516.
36. Léveillard, T., G. A. Kassavetis, and E. P. Geiduschek. 1993. Repression and redirection of S. cerevisiae tRNA synthesis from upstream of the transcription start site. J. Biol. Chem. 268:3594-3603.
37. Gln gene. J. Biol. Chem. 266:5162-5168.
38. López-de-Léon, A., M. Librizzi, K. Puglia, and I. Willis. 1992. PCF4 encodes an RNA polymerase III transcription factor with homology to TFIIB. Cell 71:211-220.
39. Marck, C., O. Lefèbvre, C. Carles, M. Riva, N. Chaussivert, A. Ruet, and A. Sentenac. 1993. The TFIIIB-assembling subunit of yeast transcription factor TFIIIC has both tetratricopeptide repeats and basic helix-loop-helix motifs. Proc. Natl. Acad. Sci. USA 90:4027-4031.
40. Margottin, F., G. Dujardin, M. Gérard, J. M. Egly, J. Huet, and A. Sentenac. 1991. Participation of the TATA factor in transcription of the yeast U6 gene by RNA polymerase C. Science 251:424-426.
41. Matsuzaki, H., G. A. Kassavetis, and E. P. Geiduschek. 1994. An analysis of RNA chain elongation and termination by S. cerevisiae RNA polymerase III. J. Mol. Biol. 235:1173-1192.
42. Parsons, M. C., and P. A. Weil. 1992. Cloning of TFC1, the Saccharomyces cerevisiae gene encoding the 95-kDa subunit of transcription factor TFIIIC. J. Biol. Chem. 267:2894-2901.
43. Rameau, G., K. Puglia, A. Crowe, I. Sethy, and I. Willis. 1994. A mutation in the second largest subunit of TFIIIC increases a rate-limiting step in transcription by RNA polymerase III. Mol. Cell. Biol. 14:822-830.
44. Roberts, S., S. J. Miller, W. S. Lane, S. Lee, and S. Hahn. 1996. Cloning and functional characterization of the gene encoding the TFIIIB90 subunit of RNA polymerase III transcription factor TFIIIB. J. Biol. Chem. 271:14903-14909.
45. Roberts, S., T. Colbert, and S. Hahn. 1995. TFIIIC determines RNA polymerase III specificity at the TATA-containing yeast U6 promoter. Genes Dev. 9:832-842.
46. Rüth, J., C. Conesa, G. Dieci, O. Lefebvre, A. Düsterhöft, S. Ottonello, and A. Sentenac. 1996. A suppressor of mutations in the class III transcription system encodes a component of yeast TFIIIB. EMBO J. 15:1941-1949.
47. Schultz, P., N. Marzouki, C. Marck, A. Ruet, P. Oudet, and A. Sentenac. 1989. The two DNA-binding domains of yeast transcription factor τ as observed by scanning transmission electron microscopy. EMBO J. 8:3815-3824.
48. Sentenac, A. Personal communication.
49. Spolar, R. S., and M. T. Record, Jr. 1994. Coupling of local folding to site-specific binding of proteins to DNA. Science 263:777-784.
50. Starr, D. B., B. C. Hoopes, and D. K. Hawley. 1995. DNA bending is an important component of site-specific recognition by the TATA binding protein. J. Mol. Biol. 250:434-446.
51. Swanson, R. N., C. Conesa, O. Lefèbvre, C. Carles, A. Ruet, E. Quemeneur, J. Gagnon, and A. Sentenac. 1991. Isolation of TFC1, a gene encoding one of two DNA-binding subunits of yeast transcription factor τ (TFIIIC). Proc. Natl. Acad. Sci. USA 88:4887-4891.
52. Werner, M., N. Chaussivert, I. M. Willis, and A. Sentenac. 1993. Interaction between a complex of RNA polymerase III subunits and the 70-kDa component of transcription factor IIIB. J. Biol. Chem. 268:20721-20724.
53. White, R. J. 1994. RNA polymerase III transcription. Molecular Biology Intelligence Unit, R. G. Landes Company, Austin, Tex.
54. Whitehall, S., G. A. Kassavetis, and E. P. Geiduschek. 1995. The symmetry of the yeast U6 RNA gene's TATA box, and the orientation of the TATA-binding protein in yeast TFIIIB. Genes Dev. 9:2974-2985.