Fast receptor-induced formation of glycerophosphoinositol-4-phosphate, a putative novel intracellular messenger in the Ras pathway

Molecular Biology of the Cell

Volumn 8, Issue 3, 1997, Pages 443-453

  Falasca, Marco ^a   Carvelli, Angela ^a   Iurisci, Cristiano ^a   Qiu, Rong Guo ^b   Symons, Marc H ^b   Corda, Daniela ^a,c  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b ONYX PHARMACEUTICALS   (United States)

^c Consorzio Mario Negri Sud ^*  (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCEROPHOSPHORYLINOSITOL 4 PHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITIDE; PHOSPHOTRANSFERASE; PROTEIN TYROSINE KINASE; RAS PROTEIN; WORTMANNIN;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; ENZYME KINETICS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0030899411     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.8.3.443     Document Type: Article

References (52)

1. Abbracchio, M.P., Paoletti, A.M., Luini, A., Cattabeni, F., and De Matteis, M.A. (1992). Adenosine receptors in rat basophilic leukaemia cells: transductional mechanism and effects on 5-hydroxytryptamine release. Br. J. Pharmacol. 105, 405-411.
2. Akiyama, T., Ishida, J., Nakagawa, S., Ogawara, H., Watanabe, S.i., Itoh, N., Shibuya, M., and Fukami, Y. (1987). Genistein, a specific inhibitor of tyrosine-specific protein kinase. J. Biol. Chem. 262, 5592-5595.
3. Alonso, T., Morgan, R.O., Marvizon, J.C., Zarbl, H., and Santos, E. (1988). Malignant transformation by ras and other oncogenes produces common alterations in inositol phospholipid signaling pathways. Proc. Natl. Acad. Sci. USA 85, 4271-4275.
4. Alonso, T., and Santos, E. (1990). Increased intracellular glycerophosphoinositol is a biochemical marker for transformation by membrane-associated and cytoplasmic oncogenes. Biochem. Biophys. Res. Commun. 372, 14-19.
5. Angus, W.W., and Lester, R.L. (1975). The regulated catabolism of endogenous and exogenous phosphatidylinositol by Saccharomyces cerevisiae leading to extracellular glycerophosphorylinositol and inositol. J. Biol. Chem. 250, 22-30.
6. Bender, J.L., and Neer, E.J. (1983). Properties of the adenylate cyclase catalytic unit from caudate nucleus. J. Biol. Chem. 258, 2432-2439.
7. Blumer, K.J., and Johnson, G.L. (1994). Diversity in function and regulation of MAP kinase pathways. Trends Biochem. Sci. 29, 236-240.
8. Bokoch, G.M., Vlahos, C.J., Wang, Y., Knaus, U.G., and Traynor-Kaplan, A.E. (1996). Rac GTPase interacts specifically with phosphatidylinositol 3-kinase. Biochem. J. 325, 775-779.
9. Bosch, F., Bouscarel, B., Slaton, J., Blackmore, P.F., and Exton, J.H. (1986). Epidermal growth factor mimics insulin effects in rat hepatocytes. Biochem. J. 239, 523-530.
10. Bunce, C.M., French, P.J., Allen, P., Mountford, J.C., Moor, B., Greaves, M.F., Michell, R.H., and Brown, G. (1993). Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts. Biochem. J. 289, 667-673.
11. Burgering, B.M.T., and Bos, J.L. (1995). Regulation of Ras-mediated signalling: more than one way to skin a cat. Trends Biochem. Sci. 20, 18-22.
12. Carpenter, G., and Cohen, S. (1990). Epidermal growth factor. J. Biol. Chem. 265, 7709-7712.
13. Cook, S.J., and McCormick, F. (1993). Inhibition by cAMP of rasdependent activation of raf. Science 262, 1069-1072.
14. 2 and inhibitory regulation of PLC. In: Handbook of Experimental Pharmacology, ed. B.F. Dickey and L. Birnbaumer. Berlin: Springer-Verlag, 387-400.
15. Corda, D., and Falasca, M. (1996). Glycerophosphoinositols as potential markers of ras-induced transformation and novel second messengers. Anticancer Res. 16, 1341-1350.
16. 2. In: GTPase-controlled Molecular Machines, ed. D. Corda, H. Hamm, and A. Luini, Rome: Ares Serono Symposia Publications, 79-91.
17. Cruz-Rivera, M., Bennet, C.F., and Crooke, S.T. (1990). Glycerol-3-phospho-D-myo-inositol 4-phosphate (Gro-PIP) is an inhibitor of phosphoinositide-specific phospholipase C. Biochim. Biophys. Acta 1042, 113-118.
18. D'Arcangelo, D., Silletta, M.G., Di Francesco, A.L., Bonfitto, N., Di Cerbo, A., Falasca, M., and Corda, D. (1995). Physiological concentrations of thyrotropin increase cytosolic calcium levels in primary cultures of human thyroid cells. J. Clin. Endocrinol. Metab. 80, 1136-1143.
19. De Matteis, M.A., Di Tullio, G., Buccione, R., and Luini, A. (1991). Characterization of calcium-triggered secretion in permeabilized rat basophilic leukemia cells. Possible role of vectorially acting G proteins. J. Biol. Chem. 266, 10452-10460.
20. Di Girolamo, M., D'Arcangelo, D., Bizzarri, C., and Corda, D. (1991). Muscarinic regulation of phospholipase A2 and iodide fluxes in FRTL-5 thyroid cells. Acta Endocrinol. 225, 192-200.
21. Dumont, J.E., Jauniaux, J.-C, and Roger, P.P. (1989). The cyclic AMP-mediated stimulation of cell proliferation. Trends Biochem. Sci. 14, 67-71.
22. Falasca, M., and Corda, D. (1994). Elevated levels and mitogenic activity of lysophosphatidylinositol in k-ras-transformed epithelial cells. Eur. J. Biochem. 222, 383-389.
23. Falasca, M., Marino, M., Carvelli, A., Iurisci, C., Leoni, S., and Corda, D. (1996). Changes in the levels of glycerophosphoinositols during differentiation of hepatic and neuronal cells. Eur. J. Biochem. 242, 386-392.
24. Falasca, M., Silletta, M.G., Carvelli, A., Di Francesco, A.L., Fusco, A., Ramakrishna, V., and Corda, D. (1995). Signalling pathways involved in the mitogenic action of lysophosphatidylinositol. Oncogene 20, 2113-2124.
25. Faure, M., and Bourne, H.R. (1995). Differential effects of cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass raf-1. Mol. Biol. Cell 6, 1025-1035.
26. Frödin, M., Peraldi, P., and Van Obberghen, E. (1994). Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells. J. Biol. Chem. 269, 6207-6214.
27. Greene, L.A., Sobeih, M.M., and Teng, K.K. (1991). 9 methodologies for the culture and experimental use of the PC12 rat pheochromocytoma cell line. In: Culturing Nerve Cells, ed. G. Banker and K. Goslin, Cambridge: MIT Press, 207-226.
28. Hawkins, P.T., Eguinoa, A., Qiu, R.-G., Stokoe, D., Cooke, F.T, Walters, R., Wennström, S., Claesson-Welsh, L., Evans, T., Symons, M., and Stephens, L. (1995). PDGF stimulates an increase in GTP-rac via activation of phosphoinositide 3-kinase. Curr. Biol. 5, 393-403.
29. Hawkins, P.T., Stephens, L.R., and Piggot, J.R. (1993). Analysis of inositol metabolites produced by Saccharomyces cerevisiae in response to glucose stimulation. J. Biol. Chem. 268, 3374-3383.
30. Iacovelli, L., Falasca, M., Valitutti, S., D'Arcangelo, D., and Corda D. (1993). Glycerophosphoinositol 4-phosphate, a putative endogenous inhibitor of adenylylcyclase. J. Biol. Chem. 268, 20402-20407.
31. Irvine, R.F. (1989). Functions of inositol phosphates. In: Inositol Lipids in Cell Signalling, ed. R.H. Michell, A.H. Drummond, and C.P. Downes, London: Academic Press, 135-161.
32. Johnson, R.M., and Garrison, J.C. (1987). Epidermal growth factor and angiotensin II stimulate formation of inositol 1,4,5-and inositol 1,3,4-trisphosphate in hepatocytes. Differential inhibition by pertussis toxin and phorbol 12-myristate 13-acetate. J. Biol. Chem. 262, 17285-17293.
33. Kobayashi, E., Nakano, H., Morimoto, M., and Tamaoki, T. (1989). Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 159, 548-553.
34. Lin, L.-L., Wartmann, M., Lin, A.Y., Knopf, J.L., Seth, A., and Davis, R.J. (1993). cPLA2 is phosphorylated and activated by MAP kinase Cell 72, 269-278.
35. Luciani, S., Antolini, M., Bova, S., Cargnelli, G., Cusinato, G., Debetto, P., Trevisi, L., and Varotto R. (1995). Inhibition of cardiac sarcolemmal sodium-calcium exchanger by glycerophosphoinositol 4-phosphate and glycerophosphoinositol 4-5-bisphosphate. Biochem. Biophys. Res. Commun. 206, 674-680.
36. McHugh Sutkowski, E., Tang, W.-J., Broome, C.W., Robbins, J.D., and Seamon, K.B. (1994). Regulation of forskolin interactions with type I, II, V, and VI adenylyl cyclases by Gsα. Biochemistry 33, 12852-12859.
37. Moolenaar, W.H. (1995). Lysophosphatidic acid, a multifunctional phospholipid messenger. J. Biol. Chem. 270, 12949-12952.
38. Mountford, J.C., Bunce, C.M., French, P.J., Michell, R.H., and Brown, G. (1994). Intracellular concentrations of inositol, glycerophosphoinositol and inositol pentakisphosphate increase during haemopoietic cell differentiation. Biochem. Biophys. Acta 1222, 101-108.
39. Neary, J.T., Rathbone, M.P., Cattabeni, F., Abbracchio, M.P., and Burnstock, G. (1996). Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells. Trends Neurosci. 39, 13-18.
40. Neary, J.T., and Zhu, Q. (1994). Signaling by ATP receptors in astrocytes. Neuroreport 5, 1617-1620.
41. 3H]-forskolin to human platelet membranes. J. Biol. Chem. 261, 13469-13473.
42. Nemenoff, R.A., Winitz, S., Qian, N.-X., Van Putten, V., Johnson, G.L., and Heasley, L.E. (1993). Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtuble-associated protein 2 kinase and protein kinase C. J. Biol. Chem. 268, 1960-1964.
43. Pang, L., Sawada, T., Decker, S.J., and Saltiel, A.R. (1995). Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J. Biol. Chem. 270, 13585-13588.
44. Parker, P.J. (1995). Intracellular signalling. PI 3-kinase puts GTP on the rac. Curr. Biol. 5, 577-579.
45. Patton, J.L., Pessoa-Brandao, L., and Henry, S.A. (1995). Production and reutilization of an extracellular phosphatidylinositol catabolite, glycerophosphoinositol, by Saccharomyces cerevisiae. J. Bacteriol. 177, 3379-3385.
46. Peppelenbosch, M.P., Qiu, R.-G., de Vries-Smits, A.M.M., Tertoolen, L.G.J., de Laat, S.W., McCormick, F., Hall, A., Symons, M.H., and Bos, J.L. (1995). Rac mediates growth factor-induced arachidonic acid release. Cell 81, 849-856.
47. Qiu, R.-G., Chen, J., Kirn, D., McCormick, F., and Symons, M. (1995). An essential role for rac in ras transformation. Nature 374, 457-459.
48. Saunier, B., Tournier, Jacquemin, C., C., and Pierre, M. (1995). Stimulation of mitogen-activated protein kinase by thyrotropin in primary cultured human thyroid follicles. J. Biol. Chem. 270, 3693-3697.
49. Spiegel, S. (1989). Inhibition of protein kinase C-dependent cellular proliferation by interaction of endogenous ganglioside GM1 with the B subunit of cholera toxin. J. Biol. Chem. 264, 16512-16517.
50. Tornquist, K., Ekokoski, E., and Dugué, B. (1996). Purinergic agonist ATP is a comitogen in thyroid FRTL-5 cells. J. Cell. Physiol. 166, 241-248.
51. 2 activity, glycerophosphoinositol production and phosphoinositide synthesis in thyroid cells. Cell. Signal. 3, 321-332.
52. Wu, J., Dent, P., Jelinek, T., Wolfman, A., Weber, M.J., and Sturgill, T.W. (1993). Inhibition of the EGF-activated MAP kinase signalling pathway by adenosine 3′,5′-monophosphate. Science 262, 1065-1069.