Rejection of islets differing by a single antigen is dependent on donor MHC

Diabetes

Volumn 46, Issue 5, 1997, Pages 765-769

  Vigneau Hermellin, Murielle ^a   Vitali, Letizia ^b   Tardivel, Isabelle ^a   Rabaud, Myriam ^a   Holers, Michael V ^c   Carel, Jean Claude ^a  

^a HÔPITAL SAINT VINCENT DE PAUL   (France)

^b UNIVERSITY OF PAVIA   (Italy)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; MAJOR HISTOCOMPATIBILITY ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; GRAFT REJECTION; GRAFT SURVIVAL; HISTOCOMPATIBILITY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; STREPTOZOCIN DIABETES; TRANSGENIC MOUSE;

EID: 0030899170     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.46.5.765     Document Type: Article

References (25)

1. Kaufman DL, Clare-Salzler M, Tian J, Forsthuber T, Ting GSP, Robinson P, Atkinson MA, Sercarz EE, Tobin AJ, Lehmann PV: Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature 366:69-72, 1993
2. Tisch R, Yang X-D, Singer SM, Liblau RS, Fugger L, McDevitt HO: Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature 366:72-75, 1993
3. Morrow CE, Sutherland DER, Steffes MW, Najarian JS, Bach FH: H-2 antigen class: effect on mouse islet allograft rejection. Science 219:1337-1339, 1983
4. Hiller WFA, Steininger B, Klempnauer J: The role of histocompatibility antigens in transplantation of isolated islets of Langerhans in the rat. Diabetes 42:90-97, 1993
5. Holers VM, Hollis GF, Schwartz BD, Evans RJ, Strauss-Schoenberger J, Carel J-C, Barney DL, Li B, Stafford-Hollis J, Lacy PE: Induction of peri-insulitis but not diabetes in islet transplants expressing a single foreign antigen: a multistage model of disease. J Immunol 151:5041-5052, 1993
6. Hourcade D, Holers VM, Atkinson JP: The regulators of complement activation (RCA) gene cluster. Adv Immunol 45:381-416, 1989
7. Molina HD, Kinoshita T, Inoue K, Carel J-C, Holers VM: A molecular and immunochemical characterization of mouse CR2: evidence for a single gene model of mouse complement receptor 1 and 2. J Immunol 147:2974-2983, 1990
8. Lipes MA, Eisenbarth GS: Perspectives in diabetes: transgenic mouse models of type 1 diabetes. Diabetes 39:879-884, 1990
9. Lacy PE, Kostianovsky M: A method for the islolation of intact islets of Langerhans from the rat pancreas. Diabetes 16:35-39, 1967
10. Carel J-C, Holers VM, Chick WL, Littmann DR, Lacy PE: Expression of a functional human Epstein-Barr virus/C3d receptor (CR2/CD21) on an insulinoma cell line induces tumor rejection but not diabetes in syngenic rats. Diabetes 40:809-814, 1991
11. Rosenberg AS: Skin allograft rejection. In Current Protocols in Immunology. Coligan JE, Krusibeek AM, Margulies DH, Shevach EM, Strober W, Eds. New York, Wiley, 1991, p. 4.4.1-4.4.12
12. Gupta S, Chowdhury NR, Jagtiani R, Gustin K, Aragona E, Shafritz DA, Chowdhury JR, Burk RD: A novel system for transplantation of isolated hepatocytes utilizing HBsAg-producing transgenic donor cells. Transplantation 50:472-475, 1990
13. Markmann JF, Lo D, Naji A, Palmiter RD, Brinster RL, Heber-Katz E: Antigen presenting function of class II MHC expressing pancreatic beta-cells. Nature 336:476-479, 1988
14. Rosay P, Hergueux J, Benoist C, Mathis D: Graft rejection across transgene-encoded MHC class II molecules. C R Acad Sci Paris 317:639-643, 1994
15. Campbell IL, Wong GHW, Schrader JW, Harrison LC: Interferon-gamma enhances the expression of the major histocompatibility class I antigens on mouse pancreatic beta cells. Diabetes 34:1205-1209, 1985
16. Carbone FR, Bevan MJ: Major histocompatibility complex control of T cell recognition. In Fundamental Immunology. 2nd ed. Paul WE, Ed. New York, Raven, 1989, p. 541-567
17. Bevan MJ: Antigen presentation to cytotoxic T lymphocytes in vivo. J Exp Med 182:639-641, 1995
18. Pfeifer JD, Wick MJ, Roberts RL, Findlay K, Normark SJ, Harding CV: Phagocytic processing of bacterial antigens for class I MHC presentation to T cells. Nature 361:359-362, 1993
19. Kovacsovics-Bankowski M, Clark K, Benacerraf B, Rock KL: Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc Natl Acad Sci USA 90:4942-4946, 1993
20. Huang AYC, Golumbek P, Ahmadzadeh M, Jaffee E, Pardoll D, Levitsky H: Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science 264:961-965, 1994
21. + T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol Today 16:34-38, 1995
22. Nickerson P, Steurer W, Steiger J, Zheng X, Steele AW, Strom TB: Cytokines and the Th1/Th2 paradigm in transplantation. Curr Opin Immunol 6:757-764, 1994
23. Anderson JT, Cornelius JG, Jarpe AJ, Winter WE, Peck AB: Insulin-dependent diabetes in the NOD mouse model II: b-cell destruction in autoimmune diabetes is a TH2 and not aTH1 mediated event Autoimmunity 15:113-122, 1993
24. Wogensen L, Lee MS, Sarvetnick N: Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice. J Exp Med 179:1379-1384, 1994
25. Gray D, Skarvall H: B cell memory is short-lived in the absence of antigen. Nature 336:70-73, 1988