Sequelae of parenteral domoic acid administration in rats: Comparison of effects on different anatomical markers in brain

Synapse

Volumn 25, Issue 4, 1997, Pages 350-358

  Appel, Nathan M ^a,b,d   Rapoport, Stanley I ^b   O'Callaghan, James P ^c  

^a Ctr for Drug Eval and Research   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

argyrophilia; astroglia; convulsion; glial fibrillary acidic protein; gliosis; Griffonia simplicifolia; immunohistochemistry; lectin histochemistry; microglia; neurotoxicity; seizure; silver

Indexed keywords

DOMOIC ACID; GLIAL FIBRILLARY ACIDIC PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARGYROPHILIA; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MACROGLIA; MALE; MICROGLIA; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; TISSUE DISTRIBUTION;

ANIMALS; ASTROCYTES; BIOLOGICAL MARKERS; BRAIN; COLORING AGENTS; GLIAL FIBRILLARY ACIDIC PROTEIN; INJECTIONS, INTRAPERITONEAL; KAINIC ACID; MALE; MICROGLIA; NEURONS; NEUROTOXINS; ORGAN SPECIFICITY; RATS; RATS, INBRED F344;

EID: 0030898729     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(199704)25:4<350::AID-SYN6>3.0.CO;2-9     Document Type: Article

References (79)

1. Appel, N.M., O'Callaghan, J.P., Freed, L.M., Wakabayashi, S., Rapoport, S.I., DeGeorge, J.J., and Contrera, J.F. (1993) Effects of domoic acid on brain metabolic markers and anatomy in rats. Soc. Neurosci. Abstr., 19:1347.
2. Appel, N.M., Rapoport, S.I., and O'Callaghan, J.P. (1994) Delayed consequences of parenteral domoic acid treatment in rat brain. Soc. Neurosci. Abstr., 20:1652.
3. Appel, N.M., Rapoport, S.I., O'Callaghan, J.P., Bell, J.M., and Freed, L.M. (1997) Sequelae of parenteral domoic acid administration in rats: Comparison of effects on different metabolic markers. Brain Res. in press.
4. Axt, K.J., Mamounas, L.A., and Molliver, M.E. (1994) Structural features of amphetamine neurotoxicity in the brain. In: Amphetamine and Its Analogs: Psychopharmacology, Toxicology, and Abuse. A.K. Cho and D.S. Segal, eds. Academic Press, pp. 315-367.
5. Bahn, S., Volk, B., and Wisden, W. (1994) Kainate receptor gene expression in the developing brain. J. Neurosci., 14:5525-5547.
6. Bates, J.F., Peake, L., Swearengen, E.S., Hall, T.W., and Standish, L.J. (1988) CL 218-872 pretreatment and intervention block kainate-induced convulsions and neuropathy. Behav. Neurosci., 102:84-92.
7. Ben-Ari, Y., Tremblay, E., Richie, D., and Naquet, R. (1981) Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: Metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy. Neuroscience, 6:1361-1391.
8. 3H] kainic acid receptor subtypes in the rat hippocampus. Neurosci. Lett., 39:237-242.
9. Boulter, J., Hollmann, M., O'Shea-Greenfield, A., Hartley, M., Deneris, E., Maron, C., and Heinemann, S. (1990) Molecular cloning and functional expression of glutamate receptor subunit genes. Science, 249:1033-1037.
10. Bruni, J.E., Bose, R., Pinsky, C., and Glavin, G. (1991) Circumventricular organ origin of domoic acid acid-induced neuropathology and toxicology. Brain Res. Bull., 26:419-424.
11. Cendes, F., Andermann, F., Carpenter, S., Zatorre, R.J., and Cashman, N.R. (1995) Temporal lobe epilepsy caused by domoic acid intoxication: Evidence for glutamate receptor-mediated excitotoxicity in humans. Ann. Neurol., 37:123-126.
12. Dakshinamurti, K., Sharma, S.K., Sundaram, M., and Watanabe, T. (1993) Hippocampal changes in developing postnatal mice following intrauterine exposure to domoic acid. J. Neurosci., 13:3386-4495.
13. Davis, E.J., Foster, T.D., and Thomas, W.E. (1994) Cellular forms and functions of brain microglia. Brain Res. Bull., 34:73-78.
14. de Feo, M.R., Mecarelli, O., Palladini, G., and Ricci, G.F. (1986) Long-term effects of early status epilepticus on the acquisition of conditioned avoidance behavior in rats. Epilepsia, 27:476-482.
15. de Olmos, J.S., Ebbesson, S.O.E., and Heimer, L. (1981) Silver methods for the impregnation of degenerating axoplasm. In: Neuroanatomical Tract-Tracing Methods. L. Heimer and M.J. Robards, eds. Plenum Press, New York, pp. 117-170.
16. Flaris, N.A., Densmore, T.L., Molleston, M.C., and Hickey, W.F. (1993) Characterization of microglia and macrophages in the central nervous system of rats: Definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction. Glia, 7:34-40.
17. Fujita, T., Tanaka, T., Yonemasu, Y., Cendes, F., Cashman, N.R., and Andermann, F. (1996) Electroclinical and pathological studies after parenteral administration of domoic acid in freely moving nonanesthetized rats: an animal model of excitotoxicity. J. Epilepsy, 9:87-96.
18. Gall, C., Sumikawa, K., and Lynch, G. (1990a) Regional distribution of mRNA for a putative kainate receptor in rat brain. Eur. J. Pharmacol., 189:217-221.
19. Gall, C., Sumikawa, K., and Lynch, G. (1990b) Levels of mRNA for a putative kainate receptor are affected by seizures. Proc. Natl. Acad. Sci. U. S. A., 87:7643-7647.
20. Greenamyre, J.T., Olson, J.M.M., Penney, J.B., Jr., and Young, A.B. (1985) Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate-and kainate-sensitive glutamate binding sites. J. Pharmacol. Exp. Then, 233:254-263.
21. 3H]glutamate-binding sites in rat central nervous system. J. Neurosci. 4:2133-2144.
22. Hampson, D.R., and Wenthold, R.J. (1988) Akainic acid receptor from frog brain purified using domoic acid affinity chromatography. J. Biol. Chem., 263:2500-2505.
23. Hsu, S.-M., Raine, L., and Fanger, H. (1981) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem., 29:577-580.
24. Iverson, F., Truelove, J., Nera, E., Tryphonas, L., Campbell J., and Lok, E. (1989) Domoic acid poisoning and mussel-associated intoxication: Preliminary investigations into the response of mice and rats to toxic mussel extract. Food Chem. Toxic., 27:377-384.
25. Johannesson, J.N. (1993) Markers of Neuronal Injury and Degeneration. New York Academy of Sciences. New York. 432 pp.
26. Kadar, T., Cohen, G., Sahar, R., Alkalai, D., and Shapira, S. (1992) Long-term study of brain lesions following soman, in comparison to DFP and metrazol poisoning. Hum. Exp. Toxicol., 11:517-523.
27. Kasof, G.M., Mandelzys, A., Maika, S.D., Hammer, R.E., Curran, T., and Morgan, J.I. (1995) Kainic acid-induced neuronal damage is associated with DNA damage and a unique immediate-early gene response in c-fos-lacZ transgenic rats. J. Neurosci., 15:4238-4249.
28. Kharazia, V., and Weinberg, R.J. (1994) Glutamate in thalamic fibers terminating in layer IV of primary sensory cortex. J. Neurosci., 14:6021-6032.
29. Loewy, A.D. (1990) Central autonomic pathways. In: Central Regulation of Autonomic Function. A.D. Loewy and K.M. Spyer, eds. Oxford University Press, New York, pp. 88-103.
30. 4 isolectin. Proc. Natl. Acad. Sci. U. S. A., 79:166-170.
31. Martin, P.M., and O'Callaghan, J.P. (1995) A direct comparison of GFAP immunocytochemistry and GFAP concentration in various regions of ethanol-fixed rat and mouse brain. J. Neurosci. Methods, 58:181-192.
32. Marty, S., Dusart, I., and Peschanski, M. (1991) Glial changes following an excitotoxic lesion in the CNS-I. Microglia/macrophages. Neuroscience, 45:529-539.
33. 3H]kainic acid binding sites in rat CNS as determined by autoradiography. Brain Res., 252:91-100.
34. 3H]glutamate-binding sites in rat brain. J. Neurosci., 5:2909-2019.
35. 3H-L-glutamate binding sites. Nature, 306:176-179.
36. Montgomery, D.L. (1994) Astrocytes: Form, functions, and roles in disease. Vet. Pathol., 31:145-167.
37. Nadler, J.V., Perry, B.W., and Cotman, C.W. (1978) Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells. Nature, 271:676-677.
38. Norenberg, M.D. (1994) Astrocyte responses to CNS injury. J. Neuropathol. Exp. Neurol., 53:213-220.
39. Norton, W.T., Aquino, D.A., Hozumi, A.I., Chiu, F.-C., and Brosnan, C.F. (1992) Quantitative aspects of gliosis: A review. Neurochem. Res., 17:877-885.
40. O'Callaghan, J.P. (1993) Quantitative features of reactive gliosis following toxicant-induced damage of the CNS. Ann. N. Y. Acad. Sci., 679:195-210.
41. O'Callaghan, J.P. (1991) Quantification of glial fibrillary acidic protein: Comparison of slot-immunoblotting assays with a novel sandwich ELISA. Neurotoxicol. Teratol., 13:275-281.
42. O'Callaghan, J.P., and Jensen, K.F. (1992) Enhanced expression of glial fibrillary acidic protein and the cupric silver degeneration reaction can be used as sensitive and early indicators of neurotoxicity. Neurotoxicology, 13:113-122.
43. O'Callaghan, J.P., Jensen, K.F., and Miller, D.B. (1995) Quantitative aspects of drug and toxicant-induced astrogliosis. Neurochem. Int., 26:115-124.
44. Okazaki, M.M., and Nadler, J.V. (1988) Protective effects of mossy fiber lesions against kainic acid-induced seizures and neuronal degeneration. Neuroscience, 26:763-781.
45. Olney, J.W., Rhee, V., and Ho, O.L. (1974) Kainic acid: A powerful neurotoxic analogue of glutamate. Brain Res., 77:507-512.
46. 3H]kainic acid binding sites in the rat brain: In vivo and in vitro receptor autoradiography. Neurosci. Lett., 70:301-307.
47. Peng, Y.G., and Ramsdell, J.S. (1996) Brain Fos induction is a sensitive biomarker for the lowest observed neuroexcitatory effects of domoic acid. Fundam. Appl. Toxicol., 31:162-169.
48. Peng, Y.G., Taylor, T.B., Finch, R.E., Switzer, R.C., and Ramsdell, J.S. (1994) Neuroexcitatory and neurotoxic actions of the amnesic shellfish poison, domoic acid. Neuroreport, 5:981-985.
49. Perl, T., Bédard, L., Remis, R., Kosatsky, T., Hoey, J., and Massé, R. (1987) Intoxication following mussel ingestion in Montreal. Can. Dis. Wkly. Rep., 12:224-226.
50. Perl, T.M., Bédard, L., Kosatsky, T., Hockin, J.C., Todd, E.C.D., and Remis, R.S. (1990) An outbreak of toxic encephalophy caused by eating mussels contaminated with domoic acid. N. Engl. J. Med., 322:1775-1780.
51. Perry, V.H., and Gordon, S. (1988) Macrophages and microglia in the nervous system. Trends Neurosci., 11:273-277.
52. Petralia, R.S., Wang, Y.-X., and Wenthold, R.J. (1994) Histological and ultrastructural localization of kainate receptor subunits, KA2 and GluR6/7, in the rat nervous system using selective antipeptide antibodies. J. Comp. Neurol., 349:85-110.
53. Piani, D., Constam, D.B., Frei, K., and Fontana, A. (1994) Macrophages in the brain: Friends or enemies? NIPS, 9:80-84.
54. Poirier, J., Gray, F., Escourolle, R., Gherardi, R.K., and Hauw, J.-J. (1990) Manual of Basic Neuropathology. W.B. Saunders, Philadelphia, pp. 1-16.
55. Pont, P., Collet, A., and Lallement, G. (1995) Early and transient increase of rat hippocampal blood-brain barrier permeability to amino acids during kainic acid-induced seizures. Neurosci. Lett., 184:52-54.
56. Preston, E., and Hynie, I. (1991) Transfer constants for blood-brain barrier permeation of the neuroexcitatory shellfish toxin, domoic acid. Can. J. Neurol. Sci., 18:39-44.
57. Robertson, H., Renton, K., Kohn, J., and White, T. (1992) Patterns of Fos expression suggest similar mechanisms of action for the excitotoxins domoic and kainic acid. Ann. N. Y. Acad. Sci., 648:330-334.
58. Saija, A., Princi, P., Pisani, A., Santoro, G., De Pasquale, R., Massi, M., and Costa, G. (1992) Blood-brain barrier dysfunctions following systemic injection of kainic acid in the rat. Life Sci., 51:467-477.
59. Scallet, A.C., Binienda, Z., Caputo, F.A., Hall, S., Paule, M.G., Rountree, R.L., Schmued, L., Sobotka, T., and Slikker, W., Jr. (1993) Domoic acid-treated cynomolgus monkeys (M. fascicularis): Effects of dose on hippocampal neuronal terminal degeneration. Brain Res., 627:307-313.
60. Schmued, L.C., Scallet, A.C., and Slikker, W. Jr. (1995) Domoic acid-induced neuronal degeneration in the primary forebram revealed by degeneration specific histochemistry. Brain Res., 695: 64-70.
61. Schwarcz, R., Scholz, D., and Coyle, J.T. (1978) Structure-activity relations for the neurotoxicity of kainic acid derivatives and glutamate analogues. Neuropharmacology, 17:145-151.
62. Schwob, J.E., Fuller, T., Price, J.L., and Olney, J.W. (1980) Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: a histological study. Neuroscience, 5:991-1014.
63. 3H]kainic acid. Brain Res., 265:169-172.
64. 4 as a marker for the line. Anat. Rec., 232:520-526.
65. Stewart, G.R., Zorumski, C.F., Price, M.Y., and Olney, J.W. (1990) Domoic acid: A dementia-inducing excitotoxic food poison with kainic acid receptor specificity. Exp. Neurol., 110:127-138.
66. Strain, S.M., and Tasker, R.A.R. (1991) Hippocampal damage produced by systemic injections of domoic acid in mice. Neuroscience, 44:343-352.
67. 4). J. Histochem. Cytochem., 38:1683-1686.
68. Streit, W.J., and Kreutzberg, G.W. (1987) Lectin binding by resting and reactive microglia. J. Neurocytol., 16:249-260.
69. Takemoto, T. (1978) Isolation and structural identification of naturally occurring excitatory amino acids. In: Kainic Acid as a Tool in Neurobiology. E.G. McGeer, J.W. Olney, and P.L. McGeer, eds. Raven Press, New York, pp. 1-15.
70. Tasker, A., and Strain, S.M. (1992) Morphine differentially affects domoic acid and kainic acid toxicity in vivo. Neuroreport, 3:789-792.
71. Tasker, R.A.R., Connell, B.J., and Strain, S.M. (1991) Pharmacology of systemically administered domoic acid in mice. Can. J. Physiol. Pharmacol., 69:378-382.
72. Teitelbaum, J.S., Zatorre, R.J., Carpenter, S., Gendron, D., Evans, A.C., Gjedde, A., and Cashman, N.R. (1990) Neurologic sequelae of domoic acid intoxication due to the ingestion of contaminated mussels. N. Engl. J. Med., 322:1781-1787.
73. Tilson, H.A., and Mitchell, C.L. (1992) Neurotoxicology. Raven Press, New York.
74. Truelove, J., and Iverson, F. (1994) Serum domoic acid clearance and clinical observations in the cynomolgus monkey and Sprague-Dawley rat following a single IV dose. Bull. Environ. Contam. Toxicol., 52:479-486.
75. Tryphonas, L., Truelove, J., and Iverson, F. (1990a) Acute parenteral neurotoxicity of domoic acid in cynomolgus monkeys (M. fascicularis). Toxicol. Pathol., 18:297-303.
76. Tryphonas, L., Truelove, J., Nera, E., and Iverson, F. (1990b) Acute neurotoxicity of domoic acid in the rat. Toxicol. Pathol., 18:1-9.
77. Wright J.L.C., Boyd, R.K., de Freitas, A.S.W., Falk, M., Foxall, R.A., Jamieson, W.D., Laycock, M.V., McCulloch, A.W., McInnes, A.G., Odense, P., Pathak, V.P., Quilliam, M.A., Ragan, M.A., Sim, P.G., Thibault, P., Walter, J.A., Bilgan, M., Richare, D.J.A., and Dewar, D. (1989) Identification of domoic acid, a neuroexcitatory amino acid, in toxic mussels from eastern Prince Edward Island. Can. J. Chem., 67:481-190.
78. Zaczek, R., and Coyle, J.T. (1982) Excitatory amino acid analogues: Neurotoxicity and seizures. Neuropharmacology, 21:15-26.
79. Zucker, D.K., Wooten, G.F., and Lothman, E.W. (1983) Blood-brain barrier changes with kainic acid-induced limbic seizures. Exp. Neurol., 79:422-433, 1983.