Intracellular disposal of incompletely folded human α1-antitrypsin involves release from calnexin and post-translational trimming of asparagine- linked oligosaccharides

Journal of Biological Chemistry

Volumn 272, Issue 12, 1997, Pages 7946-7951

  Liu, Yan ^a   Choudhury, Priya ^a   Cabral, Christopher M ^a   Sifers, Richard N ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; CALNEXIN; OLIGOSACCHARIDE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; ENZYME CONFORMATION; ENZYME RELEASE; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROCESSING;

1-DEOXYNOJIRIMYCIN; ALPHA 1-ANTITRYPSIN; ANIMALS; ASPARAGINE; CALCIUM-BINDING PROTEINS; CALNEXIN; GLUCOSE; HUMANS; MICE; OLIGOSACCHARIDES; PROTEIN FOLDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; TUMOR CELLS, CULTURED;

EID: 0030898233     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.12.7946     Document Type: Article

References (26)

1. Gething, M. J., and Sambrook, J. (1992) Nature 355, 33-45
2. Walter, P., Gilmore, R., and Blobel, G. (1984) Cell 38, 5-8
3. Klausner, R. D., and Sitia, R. (1990) Cell 62, 611-614
4. Hurtley, S. M., and Helenius, A. (1989) Annu. Rev. Cell Biol. 5, 277-307
5. Wada, I., Rindress, D., Cameron, P. H., Ou, W.-J., Doherty, J. J., II, Louvard, D., Bell, A. W., Dignard, D., Thomas, D. Y., and Bergeron, J. J. M. (1991) J. Biol. Chem. 266, 19599-19610
6. Ou, W.-J., Cameron, P. H., Thomas, D. Y., and Bergeron, J. M. (1993) Nature 364, 771-776
7. Hammond, C., Braakman, I., and Helenius, A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 913-917
8. Wada, I., Ou, W.-J., Liu, M.-C., and Scheele, G. (1994) J. Biol. Chem. 269, 7464-7472
9. Pind, S., Riordan, J. R., and Williams, D. B. (1994) J. Biol. Chem. 269, 12784-12788
10. Jackson, M. R., Cohen-Doyle, M. F., Peterson, P. A., and Williams, D. B. (1994) Science 263, 384-387
11. Hammond, C., and Helenius, A. (1994) Science 266, 456-458
12. Tector, M., and Salter, R. D. (1995) J. Biol. Chem. 270, 19638-19642
13. Kim, P. S., and Arvan, P. (1995) J. Cell Biol. 128, 29-38
14. van Leeuwen, J. E. M., and Kearse, K. P. (1996) J. Biol. Chem. 271, 9660-9665
15. Ware, F. E., Vassilakos, A., Peterson, P. A., Jackson, M. R., Lehrman, M. A., and Williams, D. B. (1995) J. Biol. Chem. 270, 4697-4704
16. Kornfeld, R., and Kornfeld, S. (1985) Annu. Rev. Biochem. 54, 631-664
17. Trombetta, S., Bosch, M., and Parodi, A. J. (1989) Biochemistry 28, 8108-8116
18. Sousa, M. C., Ferrero-Garcia, M. A., and Parodi, A. J. (1992) Biochemistry 31, 97-105
19. Trombetta, S. E, Ganan, S. and Parodi, A. J. (1991) Glycobiology 1, 155-161
20. Moore, S. E. H., and Spiro, R. G. (1993) J. Biol. Chem. 268, 3809-3812
21. Kearse, K P., Williams, D. B., and Singer, A. (1994) EMBO J. 13, 3678-3686
22. Hebert, D. N., Foellmer, B., and Helenius, A. (1995) Cell 81, 425-433
23. Ora, A., and Helenius, A. (1995) J. Biol. Chem. 270, 26060-26062
24. Sifers, R. N., Finegold, M. J., and Woo, S. L. C. (1989) Am. J. Respir. Cell Mol. Biol. 1, 341-345
25. Sifers, R. N., Finegold, M. J., and Woo, S. L. C. (1994) in The Liver: Biology and Pathobiology (Arias, I. M., Boyer, J. L., Fausto, N., Jakoby, W. B., Schachter, D. A., and Shafritz, D. A., eds) 3rd Ed., pp. 1357-1365, Raven Press, Ltd., New York
26. Carrell, R. W., and Boswell, D. R. (1986) in Proteinase Inhibitors (Barrett, A. J., and Salvesen, G., eds) pp. 403-420, Elsevier Science Publishers B. V., Amsterdam