-
1
-
-
0001776175
-
Pathways of drug metabolism
-
ed. W.B. Pratt and P. Taylor, Churchill Livingstone, New York
-
Alvares, A.P., and Pratt, W.B. (1990) Pathways of drug metabolism. In: Principles of Drug Action: The Basis of Pharmacology, ed. W.B. Pratt and P. Taylor, Churchill Livingstone, New York, pp. 365-422.
-
(1990)
Principles of Drug Action: The Basis of Pharmacology
, pp. 365-422
-
-
Alvares, A.P.A.1
Pratt, W.B.2
-
2
-
-
0024360136
-
Fen selectively and differentially decreases the density of serotonergic nerve terminals in rat brain: Evidence from immunocytochemical studies
-
Appel, N.M., Contrera, J.F., and De Souza, E.B. (1989) Fen selectively and differentially decreases the density of serotonergic nerve terminals in rat brain: Evidence from immunocytochemical studies. J. Pharmacol. Exp. Ther., 249:928-943.
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.249
, pp. 928-943
-
-
Appel, N.M.1
Contrera, J.F.2
De Souza, E.B.3
-
3
-
-
0025090790
-
Effects of high-dose fenfluramine treatment on monoamine uptake sites in rat brain: Assessment using quantitative autoradiography
-
Appel, N.M., Mitchell, W.M., Contrera, J.F., and De Souza, E.B. (1990) Effects of high-dose fenfluramine treatment on monoamine uptake sites in rat brain: Assessment using quantitative autoradiography. Synapse, 6:33-44.
-
(1990)
Synapse
, vol.6
, pp. 33-44
-
-
Appel, N.M.1
Mitchell, W.M.2
Contrera, J.F.3
De Souza, E.B.4
-
4
-
-
0027989865
-
Report on the NIH workshop on pharmacologic treatment of obesity
-
Atkinson, R.L., and Hubbard, V.S. (1994) Report on the NIH workshop on pharmacologic treatment of obesity. Am. J. Clin. Nutr., 60:153-156.
-
(1994)
Am. J. Clin. Nutr.
, vol.60
, pp. 153-156
-
-
Atkinson, R.L.1
Hubbard, V.S.2
-
6
-
-
0024159060
-
MDMA-induced neurotoxicity: Parameters of degeneration and recovery of brain serotonin neurons
-
Battaglia, G., Yeh, S.Y., and De, S.E.B. (1988) MDMA-induced neurotoxicity: Parameters of degeneration and recovery of brain serotonin neurons. Pharmacol. Biochem. Behav. 29:269-274.
-
(1988)
Pharmacol. Biochem. Behav.
, vol.29
, pp. 269-274
-
-
Battaglia, G.1
Yeh, S.Y.2
De, S.E.B.3
-
7
-
-
0026802919
-
[125]RTI-55 to dopamine and serotonin transporters in rat brain
-
[125]RTI-55 to dopamine and serotonin transporters in rat brain. Synapse, 12:27-36.
-
(1992)
Synapse
, vol.12
, pp. 27-36
-
-
Boja, J.W.1
Mitchell, W.M.2
Patel, A.3
Kopajtic, T.A.4
Carroll, F.I.5
Lewin, A.H.6
Abraham, P.7
Kuhar, M.J.8
-
8
-
-
0019968741
-
Species differences in the kinetics and metabolism of fenfluramine isomers
-
Caccia, S., Ballabio, M., Guiso, G., Rocchetti, M., and Garattini, S. (1982) Species differences in the kinetics and metabolism of fenfluramine isomers. Arch. Int. Pharmacodyn., 258:15-28.
-
(1982)
Arch. Int. Pharmacodyn.
, vol.258
, pp. 15-28
-
-
Caccia, S.1
Ballabio, M.2
Guiso, G.3
Rocchetti, M.4
Garattini, S.5
-
9
-
-
0017083601
-
Anorectic drugs: Use in general practice
-
Craddock, D. (1976) Anorectic drugs: Use in general practice. Drugs, 11:378-393.
-
(1976)
Drugs
, vol.11
, pp. 378-393
-
-
Craddock, D.1
-
10
-
-
0013909023
-
Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey and man
-
Freireich, E.J., Gehan, E.A., Rail, D.P., Schmidt, L.H., and Skipper, H.E. (1966) Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey and man. Cancer Cherother. Rep. 50:219-226.
-
(1966)
Cancer Cherother. Rep.
, vol.50
, pp. 219-226
-
-
Freireich, E.J.1
Gehan, E.A.2
Rail, D.P.3
Schmidt, L.H.4
Skipper, H.E.5
-
11
-
-
0016682258
-
Fenfluramine: Evidence for a neurotoxic action on a long-term depletion of serotonin
-
Harvey, J.A., and McMaster, S.E. (1975) Fenfluramine: Evidence for a neurotoxic action on a long-term depletion of serotonin. Psychopharmacol. Commun., 1:217-228.
-
(1975)
Psychopharmacol. Commun.
, vol.1
, pp. 217-228
-
-
Harvey, J.A.1
McMaster, S.E.2
-
12
-
-
0017729454
-
Fenfluramine: Cumulative neurotoxicity after chronic treatment with low dosages in the rat
-
Harvey, J.A. and McMaster, S.E. (1977) Fenfluramine: Cumulative neurotoxicity after chronic treatment with low dosages in the rat. Commun. Psychopharmacol., 1:3-17.
-
(1977)
Commun. Psychopharmacol.
, vol.1
, pp. 3-17
-
-
Harvey, J.A.1
McMaster, S.E.2
-
13
-
-
0017704594
-
Comparison between the neurotoxic and serotonin depleting effects of various halogenated derivatives of amphetamine in the rat
-
Harvey, J.A., McMaster, S.E., and Fuller, R.W. (1977) Comparison between the neurotoxic and serotonin depleting effects of various halogenated derivatives of amphetamine in the rat. J. Pharmacol. Exp. Ther., 202:581-589.
-
(1977)
J. Pharmacol. Exp. Ther.
, vol.202
, pp. 581-589
-
-
Harvey, J.A.1
McMaster, S.E.2
Fuller, R.W.3
-
14
-
-
0018965414
-
A rapid method for the regional dissection of the rat brain
-
Heffner, T.G., Hartman, J.A., and Seiden, L.S. (1980) A rapid method for the regional dissection of the rat brain. Pharmacol. Biochem. Behav. 13:453-456.
-
(1980)
Pharmacol. Biochem. Behav.
, vol.13
, pp. 453-456
-
-
Heffner, T.G.1
Hartman, J.A.2
Seiden, L.S.3
-
15
-
-
0028557961
-
Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ("ecstasy") to rats
-
Hewitt, K.E., and Green, A.R. (1994) Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ("ecstasy") to rats. Neuropharmacology, 33:1589-1595.
-
(1994)
Neuropharmacology
, vol.33
, pp. 1589-1595
-
-
Hewitt, K.E.1
Green, A.R.2
-
16
-
-
0024951451
-
Microdialysis studies of brain norepinephrine, serotonin, and dopamine release during ingestive behavior. Theoretical and clinical implications
-
Hoebel, B.C., Hernandez, L., Schwartz, D.H., Mark, G.P., and Hunter, G.A. (1989) Microdialysis studies of brain norepinephrine, serotonin, and dopamine release during ingestive behavior. Theoretical and clinical implications. Ann. N.Y. Acad. Sci., 575:171-191.
-
(1989)
Ann. N.Y. Acad. Sci.
, vol.575
, pp. 171-191
-
-
Hoebel, B.C.1
Hernandez, L.2
Schwartz, D.H.3
Mark, G.P.A.4
Hunter, G.A.5
-
17
-
-
0024788704
-
D-, L- and DL-fenfluramine cause long-lasting depletions of serotonin in rat brain
-
Kleven, M.S., and Seiden, L.S. (1989) D-, L- and DL-fenfluramine cause long-lasting depletions of serotonin in rat brain. Brain Res., 505:351-353.
-
(1989)
Brain Res.
, vol.505
, pp. 351-353
-
-
Kleven, M.S.1
Seiden, L.S.2
-
18
-
-
0023724530
-
Effect of depletion of brain serotonin by repeated fenfluramine on neurochemical and anorectic effects of acute fenfluramine
-
Kleven, M.S., Schuster, C.R., and Seiden, L.S. (1988) Effect of depletion of brain serotonin by repeated fenfluramine on neurochemical and anorectic effects of acute fenfluramine. J. Pharmacol. Exp. Ther. 246:822-828.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.246
, pp. 822-828
-
-
Kleven, M.S.1
Schuster, C.R.2
Seiden, L.S.3
-
19
-
-
0007397241
-
Evaluation of potential neurotoxic effects of amphetamine-related anorectic agents on brain serotonin and dopamine in the rat
-
Kleven, M.S., Woolverton, W.L., and Seiden, L.S. (1991) Evaluation of potential neurotoxic effects of amphetamine-related anorectic agents on brain serotonin and dopamine in the rat. Proc. Soc. Neurosci., 17:1488.
-
(1991)
Proc. Soc. Neurosci.
, vol.17
, pp. 1488
-
-
Kleven, M.S.1
Woolverton, W.L.2
Seiden, L.S.3
-
20
-
-
0025014798
-
Anatomic evidence for a neurotoxic effect of (±)-fenfluramine upon serotonergic projections in the rat
-
Molliver, D.C., and Molliver, M.E. (1990) Anatomic evidence for a neurotoxic effect of (±)-fenfluramine upon serotonergic projections in the rat. Brain Res., 511:165-168.
-
(1990)
Brain Res.
, vol.511
, pp. 165-168
-
-
Molliver, D.C.1
Molliver, M.E.2
-
21
-
-
0019061918
-
LIGAND: A versatile approach for characterization of ligand-binding systems
-
Munson, P.J., and Rodbard, D. (1980) LIGAND: A versatile approach for characterization of ligand-binding systems. Anal. Biochem., 107:220-239.
-
(1980)
Anal. Biochem.
, vol.107
, pp. 220-239
-
-
Munson, P.J.1
Rodbard, D.2
-
22
-
-
0002538201
-
Dose-time-effect relationships
-
R.J.M. Niesink, J. de. Vries, and M.A. Hollinger, eds. CRC Press, Boca Raton, New York, London, and Tokyo
-
Musch, A. (1996) Dose-time-effect relationships. In: Toxicology: Principles and Applications. R.J.M. Niesink, J. de. Vries, and M.A. Hollinger, eds. CRC Press, Boca Raton, New York, London, and Tokyo, pp 187-237.
-
(1996)
Toxicology: Principles and Applications
, pp. 187-237
-
-
Musch, A.1
-
23
-
-
0028061499
-
Multiple serotonin receptors: Clinical and experimental aspects
-
Roth, B.L. (1994) Multiple serotonin receptors: Clinical and experimental aspects. Ann. Clin. Psychiatry, 6:67-78.
-
(1994)
Ann. Clin. Psychiatry
, vol.6
, pp. 67-78
-
-
Roth, B.L.1
-
24
-
-
10544240003
-
Fenfluramine-induced loss of serotonin transporters in baboon brain visualized with PET
-
Scheffel, U., Szabo, Z., Mathews, W.B., Finley, P.A., Yuan, J., Callahan, B., Hatzidimitriou, G., Dannals, R.F., Ravert, H.T., and Ricaurte, G.A. (1996) Fenfluramine-induced loss of serotonin transporters in baboon brain visualized with PET. Synapse, 24, 395-398.
-
(1996)
Synapse
, vol.24
, pp. 395-398
-
-
Scheffel, U.1
Szabo, Z.2
Mathews, W.B.3
Finley, P.A.4
Yuan, J.5
Callahan, B.6
Hatzidimitriou, G.7
Dannals, R.F.8
Ravert, H.T.9
Ricaurte, G.A.10
-
25
-
-
0021800026
-
Role of dopamine in the neurotoxic effects of methamphetamine
-
Schmidt, C.J., Ritter, J.K., Sonsalla, P.K., Hanson, G.R., and Gibb, J.W. (1985) Role of dopamine in the neurotoxic effects of methamphetamine. J. Pharmacol. Exp. Ther., 233:539-544.
-
(1985)
J. Pharmacol. Exp. Ther.
, vol.233
, pp. 539-544
-
-
Schmidt, C.J.1
Ritter, J.K.2
Sonsalla, P.K.3
Hanson, G.R.4
Gibb, J.W.5
-
26
-
-
0022613125
-
Fenfluramine: Neurotoxicity
-
Schuster, C.R., Lewis, M., and Seiden, L.S. (1986) Fenfluramine: Neurotoxicity. Psychopharmacol. Bull., 22:148-151.
-
(1986)
Psychopharmacol. Bull.
, vol.22
, pp. 148-151
-
-
Schuster, C.R.1
Lewis, M.2
Seiden, L.S.3
-
27
-
-
0026680624
-
Appetite suppressants. A review
-
Silverstone, T. (1992) Appetite suppressants. A review. Drugs, 43:820-836.
-
(1992)
Drugs
, vol.43
, pp. 820-836
-
-
Silverstone, T.1
-
28
-
-
0026593859
-
Long-term weight control study: Conclusions
-
Weintraub, M.D., (1992) Long-term weight control study: Conclusions. Clin. Pharmacol. Ther., 51:642-646.
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 642-646
-
-
Weintraub, M.D.1
-
29
-
-
0021242404
-
A double-blind clinical trial in weight control. Use of fenfluramine and phentermine alone and in combination
-
Weintraub, M.D., Hasday, J.D., Mushlin, A.I., and Lockwood, D.H. (1984) A double-blind clinical trial in weight control. Use of fenfluramine and phentermine alone and in combination. Arch. Intern. Med., 144:1143-1148.
-
(1984)
Arch. Intern. Med.
, vol.144
, pp. 1143-1148
-
-
Weintraub, M.D.1
Hasday, J.D.2
Mushlin, A.I.3
Lockwood, D.H.4
-
30
-
-
0026518794
-
Long-term weight control study. I (weeks 0 to 34). The enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placebo
-
Weintraub, M.D., Sundaresan, P.R., Madan, M., Schuster, B., Balder, A., Lasagna, L., and Cox. C. (1992a) Long-term weight control study. I (weeks 0 to 34). The enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placebo. Clin. Pharmacol. Ther., 51:586-594.
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 586-594
-
-
Weintraub, M.D.1
Sundaresan, P.R.2
Madan, M.3
Schuster, B.4
Balder, A.5
Lasagna, L.6
Cox, C.7
-
31
-
-
0026589037
-
Long-term weight control study. V (weeks 190 to 210). Follow-up of participants after cessation of medication
-
Weintraub, M.D., Sundaresan, P.R., Schuster, B., Averbuch, M., Stein, E.C., and Byrne, L. (1992b) Long-term weight control study. V (weeks 190 to 210). Follow-up of participants after cessation of medication. Clin. Pharmacol. Ther., 51:615-618.
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 615-618
-
-
Weintraub, M.D.1
Sundaresan, P.R.2
Schuster, B.3
Averbuch, M.4
Stein, E.C.5
Byrne, L.6
-
32
-
-
0026544763
-
Long-term weight control study. IV (weeks 156 to 190). The second double-blind phase
-
Weintraub, M.D., Sundaresan, P.R., Schuster, B., Averbuch, M., Stein, E.C., Cox, C., and Byrne. L. (1992c) Long-term weight control study. IV (weeks 156 to 190). The second double-blind phase. Clin. Pharmacol. Ther. 51:608-614.
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 608-614
-
-
Weintraub, M.D.1
Sundaresan, P.R.2
Schuster, B.3
Averbuch, M.4
Stein, E.C.5
Cox, C.6
Byrne, L.7
-
33
-
-
0026593857
-
Long-term weight control study. II (weeks 34 to 104). An open-label study of continuous fenfluramine plus phentermine versus targeted intermittent medication as adjuncts to behavior modification, caloric restriction, and exercise
-
Weintraub, M.D., Sundaresan, P.R., Schuster, B., Ginsberg, G., Madan, M., Balder, A., Stein, E.C., and Byrne, L. (1992d) Long-term weight control study. II (weeks 34 to 104). An open-label study of continuous fenfluramine plus phentermine versus targeted intermittent medication as adjuncts to behavior modification, caloric restriction, and exercise. Clin. Pharmacol. Ther. 51:595-601.
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 595-601
-
-
Weintraub, M.D.1
Sundaresan, P.R.2
Schuster, B.3
Ginsberg, G.4
Madan, M.5
Balder, A.6
Stein, E.C.7
Byrne, L.8
-
34
-
-
0026531965
-
Long-term weight control study. III (weeks 104 to 156). An open-label study of dose adjustment of fenfluramine and phentermine
-
Weintraub, M.D., Sundaresan, P.R., Schuster, B., Moscucci, M., and Stein, B.C. (1992e) Long-term weight control study. III (weeks 104 to 156). An open-label study of dose adjustment of fenfluramine and phentermine. Clin. Pharmacol. Ther. 51:602-607.
-
(1992)
Clin. Pharmacol. Ther.
, vol.51
, pp. 602-607
-
-
Weintraub, M.D.1
Sundaresan, P.R.2
Schuster, B.3
Moscucci, M.4
Stein, B.C.5
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