Vitamin D receptor genotypes and changes of bone density in physically active German women with high calcium intake

Experimental and Clinical Endocrinology and Diabetes

Volumn 105, Issue 2, 1997, Pages 103-108

  Rauch, F ^a   Radermacher, A ^a   Danz, A ^a   Schiedermaier, U ^a   Golucke A ^a   Michalk, D ^a   Schonau E ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Bone density; Bone metabolism; Vitamin D receptor

Indexed keywords

ALKALINE PHOSPHATASE; OSTEOCALCIN; PROCOLLAGEN; VITAMIN D RECEPTOR;

ADULT; ARTICLE; BONE DENSITY; BONE METABOLISM; BONE MINERAL; BONE TURNOVER; CALCIUM INTAKE; CLINICAL ARTICLE; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LONGITUDINAL STUDY; NORMAL HUMAN; PHYSICAL ACTIVITY; POPULATION GENETICS; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL;

EID: 0030897930     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0029-1211735     Document Type: Article

References (34)

1. Akesson K, Ljunghall S, Jonsson B, Sernbo I, Johnell O, Gärdsell P, Obrant KJ: Assessment of biochemical markers of bone metabolism in relation to the occurrence of fracture: A retrospective and prospective population-based study of women. J Bone Miner Res 10: 1823-1829, 1995
2. Bergmeyer HU, Büttner H, Hillmann G, Kreutz FH, Lang H, Laue D, Pilz W, Rick W, Schmidt E, Schmidt FW, Stamm D, Szasz G: Empfehlungen der Deutschen Gesellschaft für Klinische Chemie. Standardisierung von Methoden zur Bestimmung von Enzymaktivitäten in biologischen Flüssigkeiten. Experimentelle Begründung der optimierten Standard-Bedingungen. Z Klin Chem Klin Biochem 10: 182-192, 1972
3. Cummings SR, Nevitt MC, Browner WS, Stone K, Fox KM, Ensrud KE, Cauley J, Black D, Vogt TM: Risk factors for hip fracture in white women. New Engl J Med 332: 767-773, 1995
4. Dawson-Hughes B, Harris SS, Finneran S: Calcium absorption on high and low calcium intakes in relation to vitamin D receptor genotype. J Clin Endocrinol Metab 80: 3657-3661, 1995
5. Eisman JA: Editorial. Vitamin D receptor gene alleles and osteoporosis: An affirmative view. J Bone Miner Res 10: 1289-1293, 1995
6. Ferrari SL, Rizzoli R, Chevally T, Slosman D, Eisman JA, Bonjour JP: Vitamin-D-receptor-gene polymorphisms and change in lumbar-spine bone mineral density. Lancet 345:423-424, 1995
7. Fleet JC, Harris SS, Wood RJ, Dawson-Hughes B: The Bsm I vitamin D receptor restriction fragment length polymorphism (BB) predicts low BMD in premenopausal black and white women. J Bone Miner Res 10: 985-990, 1995
8. Garnero P, Borel O, Sornay-Rendu E, Delmas PD: Vitamin D receptor gene polymorphisms do not predict peak bone turnover and bone mass in healthy premenopausal women. J Bone Miner Res 10: 1283-1288, 1995
9. Gregg EW, Cauley JA, Salamone LM, Black D, Ferell R, Epstein R: The relationship between vitamin D receptor gene polymorphisms and bone quality in pre- and perimenopausal women. J Bone Miner Res 10 (Suppl. 1): S366, 1995
10. Hustmyer FG, Peacock M, Hui S, Johnston CC, Christian J: Bone mineral density in relation to polymorphism at the vitamin D receptor gene locus. J Clin Invest 94: 2130-2134, 1994
11. Kastenbaum MA, Hoel DG: Sample size requirements: one-way analysis of variance. Biometrika 57: 421-430, 1970
12. Keen RW, Egger P, Major PJ, Spector TD, Cooper C: Polymorphisms of the vitamin D receptor, infant growth and adult bone mass. J Bone Miner Res 10 (Suppl. 1): S189, 1995
13. Kelly PJ, Hopper JL, Macaskill GT, Pocock NA, Sambrook PN, Eisman JA: Genetic factors in bone turnover. J Clin Endocrinol Metab 72: 808-813, 1992
14. Krall EA, Parry P, Lichter JB, Dawson-Hughes B: Vitamin D receptor alleles and rates of bone loss: Influences of years since menopause and calcium intake. J Bone Miner Res 10: 978-984, 1995
15. Kröger H, Mahonen A, Ryhanen S, Turumen AM, Alhava E, Maenpaa P: Vitamin D receptors and bone mineral density. Lancet 345: 1239, 1995
16. Lander ES, Schork NJ: Genetic dissection of complex traits. Science 265: 2037-2048, 1994
17. Lehmann R, Wapniarz M, Kvasnicka HM, Baedeker S, Klein K, Allolio B: Reproducibility of measurements of bone mineral density of the distal radius with a special-purpose computed tomography scanner. Radiologe 32: 177-181, 1992
18. Lim SK, Park YS, Park JM, Song YD, Lee EJ, Kim KR, Lee HC, Huh KB. Lack of association between vitamin D receptor genotypes and osteoporosis in Koreans. J Clin Endocrinol Metab 80: 3677-3681, 1995
19. Looney JE, Yoon HK, Fischer M, Farley SM, Farley JR, Weredal JE, Baylink DJ: Lack of a high prevalence of the BB vitamin D receptor genotype in severely osteoporotic women. J Clin Endocrinol Metab 80: 2158-2162, 1995
20. Morrison NA, Qi JC, Tokita A, Kelly PJ, Crofts L, Nguyen TV, Sambrook PN, Eisman JA: Prediction of BMD from vitamin D receptor alleles. Nature 367: 284-287, 1994
21. Morrison NA, Yeoman R, Kelly PJ, Eisman JA: Contribution of trans-acting factor alleles to normal physiological variability: Vitamin D receptor gene polymorphisms and circulating osteocalcin. Proc Natl Acad Sci USA 89: 6665-6669, 1992
22. Peacock M: Editorial. Vitamin D receptor gene alleles and osteoporosis: A contrasting view. J Bone Miner Res 10: 1294-1297, 1995
23. Riggs BL, Nauyen TV, Melton LJ, Morrison NA, O'Fallow WM, Kelly PJ, Egan KS, Sambrook PN, Muhs JM. Eisman JA: The contribution of vitamin D receptor gene alleles to the determination of bone mineral density in normal and osteoporotic women. J Bone Miner Res 10: 991-996, 1995
24. Risteli J, Elomaa I, Niemi S, Novamo A, Risteli L: Radioimmunoassay for the pyridinoline cross-links carboxyterminal telopeptide of type I collagen: A new serum marker of bone collagen degradation. Clin Chem 39: 635-640, 1993
25. Salamone LM, Ferrell R, Black DM, Epstein RS, Petro N, Steadman N, Kuller LH, Cauley JA: The association between vitamin D receptor gene polymorphisms and bone mineral density at the spine, hip and whole-body in premenopausal women. Osteoporosis Int 6: 63-68, 1996
26. Schneider P, Börner W: Periphere quantitative Computer-tomographie zur Knochenmineralmessung mit einem neuen speziellen QCT-Scanner. ROFO 154: 292-299, 1991
27. Schøller J, Jørgensen HL, Sand JC, Jensen M, Hassager C, Christiansen C: The impact of common allelic variation at the vitamin D receptor locus on bone mass is not clinically relevant. J Bone Miner Res 10 (Suppl. 1): S161, 1995
28. a) Schönau E, Radermacher A, Wentzlik U, Klein K, Michalk D: The determination of ultrasound velocity in the os calcis, thumb and patella during childhood. Eur J Pediatr 153: 252-256, 1994
29. b) Schönau E, Wentzlik U, Radermacher A, Keuth B, Michalk D, Scheidhauer K: Measurement of density and structure in bones. Lancet 343: 1635-1636, 1994
30. Seeman E, Hopper JL, Bach LA, Cooper ME, Parkinson E, McKay J, Jerums G: Reduced bone mass in daughters of women with osteoporosis. N Engl J Med 320: 554-558, 1989
31. Smith DM, Nance WE, Kang KW, Christian JC, Johnston CC: Genetic factors in determining bone mass. J Clin Invest 52: 2800-2808, 1973
32. Spector TD, Keen RW, Arden NK, Morrison NA, Major PJ, Nguyen TV, Kelly PJ, Baker JR, Sambrook PN, Lanchbury JS, Eisman JA: Influence of vitamin D receptor genotype on bone mineral density in postmenopausal women: a twin study in Britain. BMJ 310: 1357-1360, 1995
33. Tokita A, Kelly PJ, Nguyen TV, Qi JC, Morrison NA, Risteli L, Risteli J, Sambrook PN, Eisman JA: Genetic influences on type I collagen synthesis and degradation: Further evidence for genetic regulation of bone turnover. J Clin Endocrinol Metab 78: 1461-1466, 1994
34. Tokita A, Tawa T, Miura Y, Yabuta K, Matsumoto H, Miura M, Watanabe T, Morrison NA, Eisman JA: Vitamin D receptor alleles, bone mineral density and bone turnover in Japanese. J Bone Miner Res 10 (Suppl. 1): S185, 1995