Expression of wild-type p53 tumor suppressor gene and its possible involvement in the apoptosis of thyroid tumors

Surgery Today

Volumn 27, Issue 3, 1997, Pages 226-233

  Kikuchi, Shoichi ^a   Hiraide, Hoshio ^a   Tamakuma, Shoetsu ^a   Yamamoto, Mikio ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

apoptosis; papillary carcinoma of the thyroid; wild type p53

Indexed keywords

PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER SURVIVAL; HUMAN; HUMAN TISSUE; PAPILLARY CARCINOMA; THYROID CARCINOMA; THYROID TUMOR; TUMOR SUPPRESSOR GENE;

APOPTOSIS; BASE SEQUENCE; CARCINOMA, PAPILLARY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENES, P53; GENES, TUMOR SUPPRESSOR; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; PROGNOSIS; THYROID NEOPLASMS;

EID: 0030897880     PISSN: 09411291     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00941650     Document Type: Article

References (44)

1. George SL (1986) Nodular goiter and benign and malignant neoplasms of the thyroid. In: Sabiston DC (ed) Textbook of surgery, vol 1. Saunders, Philadelphia, pp 595-610
2. Raff MC (1992) Social controls on cell survival and cell death. Nature 356:397-400
3. Williams GT (1991) Programmed cell death: apoptosis and oncogenesis. Cell 65:1097-1098
4. Marx J (1993) Cell death studies yield cancer clues. Science 259:760-761
5. Kerr JFR, Wyllie AH, Currie AR (1972) Apoptosis: A basic-biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-245
6. Kerr JFR, Winterford CM, Harmon BV (1994) Apoptosis. Cancer 73:2013-2026
7. Hollstein M, Sidransky D, Vogelstein B, Harris CC (1991) p53 mutations in human cancers. Science 252:49-53
8. Levine AJ, Momand J, Finlay CA (1991) The p53 tumour suppressor gene. Nature 351:453-456
9. Varda R, Miron P (1991) p53 and human malignancies. Adv Cancer Res 57:257-272
10. Oren M, Reich NC, Levine AJ (1982) Regulation of the p53 tumor antigen in teratocarcinoma cells and their differentiated progeny. Mol Cell Biol 2:443-449
11. Mercer WE, Avignolo C, Baserga R (1984) Role of the p53 protein in cell proliferation as studied by microinjection of monoclonal antibodies. Mol Cell Biol 4:276-281
12. Finlay CA, Hinds PW, Tan TH, Eliyahu D, Oren M, Levine AJ (1988) Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half life. Mol Cell Biol 8:531-539
13. Fritsche M, Haessler C, Brandner G (1993) Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene 8:307-318
14. Lane DP (1992) p53, guardian of the genome. Nature 358: 15-16
15. Shaw P, Bovery R, Tardy S, Sahli R, Sordat B, Costa J (1992) Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. Proc Natl Acad Sci USA 89:4495-4499
16. Fujiwara T, Grimm EA, Mukhopadhyay T, Zhang WW, Owen-Schaub LB, Roth JA (1994) Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene. Cancer Res 54:2287-2291
17. Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T (1993) p53 is required for radiation-induced apoptosis in mouse thymoeytes. Nature 362:847-848
18. Barry MA, Behnke CA, Eastman A (1990) Activation of programmed cell death by cisplatin. other anticancer drugs, toxins and hyperthermia. Biochem Pharmacol 40:2353-2362
19. Chomezynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
20. Wakatsuki T, Kimura K, Kimura F, Shinomiya N, Ohtsubo M, Ishizawa M, Yamamoto M (1995) A distinct mRNA encoding a soluble form of ICAM-1 molecule expressed in human tissues. Cell Adh Commun 3:283-292
21. Hsu SM, Rainel L, Fanger H (1981) A comparative study of the peroxidase-antiperoxidase method and an avidin-biotin complex method for studying peptide hormones with radioimmunoassay antibodies. Am J Clin Pathol 75:734-738
22. y antigen expression is correlated with apoptosis (programmed cell death). Glycobiology 3:381-390
23. Oren M (1992) p53: the ultimate tumor suppressor gene? FASEB J 6:169-176
24. Ginsberg D, Michael-Miehalovitz D, Ginsberg D, Pren M (1991) Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein. Mol Cell Biol 11:582-585
25. Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hosteller R, Cleary K, Biggner SH, Davidson N, Baylin S, Devilee P, Glover T, Collins FS, Weston A, Modali R, Harris CC, Vogelstein B (1989) Mutations in the p53 gene occur in diverse human tumour types. Nature 342:705-708
26. Harris CC, Hollstein M (1993) Clinical implications of the p53 tumor suppressor gene. N Engl J Med 329:1318-1327
27. Greenblatt MS, Bennet WP, Hollstein M, Harris CC (1994) Mutations in the p53 tumor suppressor gene; clue to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878
28. Van Meri EG, Polverini PJ (1994) Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cell. Nature Genet 8:171-176
29. Bedi A, Pasricha PJ, Akhtas AJ, Barber JP, Bedi GC, Giardiella FM, Zehnbader BA, Hamilton SR, Jones RJ (1995) Inhibition of apoptosis during development of colorectal cancer. Cancer Res 55:1811-1816
30. Miyashita T, Krajewski S, Krajierska M, Wang HG, Lin HK, Liebermann DA, Hoffman B, Read JC (1994) Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and vivo. Oncogene 9:1799-1805
31. Miyashita T, Reed JC (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293-299
32. Fasin JA (1992) Genetic basis of endocrine disease 3: molecular defects in thyroid gland neoplasia. J Clin Endocrinol Metab 75:1398-1400
33. Fasin JA (1993) High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J Clin Invest 91:179-184
34. Shimizu T (1993) Proliferative activity of human thyroid tumors evaluated by proliferating cell nuclear antigen/cyclin immunohistochemical studies. Cancer 71:2807-2812
35. Haugen DFR, Akslen LA, Varhaug JE, Lillehaug JR (1992) Expression of c-erbB2 protein in papillary thyroid carcinomas. Br J Cancer 65:832-837
36. Aasland R, Lillehaug JR, Male R, Josendal O, Varhaug JE, Kleppe K (1988) Expression of oncogenes in thyroid tumors: Coexpression of c-erbB2/neu and c-erbB. Br J Cancer 57:358-363
37. Hsu H, Xiong J, Goeddel DV (1995) The TNF receptor 1-associated protein TRADD signals cell death and NF-kB activation. Cell 81:495-504
38. Nagata S, Golstein P (1995) The Fas death factor. Science 267:1449-1456
39. Cheng J, Zhou T, Liu C, Shanpiro JP, Brauer MJ, Kiefer MC, Barr PJ, Mountz JD (1994) Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science 263:1759-1762
40. Hockenbery DM, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ (1990) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-336
41. Fanidi A, Harrington EA, Evan GI (1992) Cooperative interaction between c-myc and bcl-2 and proto-oncogenes. Nature 359:554-556
42. Frank A (1995) bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis. Cancer Res 55:237-241
43. Pilotti S, Collini P, Rilke F, Cattoretti G, Bo RD, Pierotti MA (1994) Bcl-2 protein expression in carcinomas originating from the follicular epithelium of the thyroid gland. J Pathol 172:337-342
44. Tanimoto C, Hirakawa S, Kawasaki H, Hayakawa N. Ota Z (1995) Apoptosis in thyroid disease; A histochemical study. Endocrine J 42:193-201