Secretion of biologically active superantigens by mammalian cells

Journal of Hematotherapy and Stem Cell Research

Volumn 6, Issue 1, 1997, Pages 41-51

  Krauss, John C ^a   Shu, Suyu ^b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

SUPERANTIGEN; VIRUS DNA;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CANCER IMMUNOLOGY; EXPRESSION VECTOR; GENE TARGETING; GENE THERAPY; GENETIC TRANSFORMATION; IMMUNOREGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RETROVIRUS; T LYMPHOCYTE ACTIVATION;

EID: 0030897642     PISSN: 15258165     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.1.1997.6.41     Document Type: Article

References (35)

1. Fleischer, B. Superantigens. Acta Pathol. Microbiol. Immunol. Scand. 102:3, 1994.
2. Carlsson, R. & Sjögren, H.O. Kinetics of IL-2 and interferon-γ production, expression of IL-2 receptors, and cell proliferation in human mononuclear cells exposed to staphylococcal enterotoxin A. Cell. Immunol. 96:175, 1985.
3. Callahan, J.E., Herman, A., Kappler, J.W., et al. Stimulation of B10.BR T cells with superantigen staphylococcal toxins. J. Immunol. 144:2473, 1990.
4. Shu, S., Sussman, J. & Chang A.E. In vivo antitumor efficacy of tumor-draining lymph node cells activated with nonspecific T-cell reagents. J. Immunother. 14:279, 1993.
5. Takimoto, H., Yoshikai, Y., Kishihara, K., et al. Stimulation of all T cells bearing Vβ1, Vβ3, Vβ11 and Vβ12 by staphylococcal enterotoxin A. Eur. J. Immunol. 20:617, 1990.
6. b molecules on macrophages. Proc. Natl. Acad. Sci. USA 92:6294, 1995.
7. Lee, P.K. & Schlievert, P.M. Molecular genetics of pyrogenic exotoxin "superantigens" of group A streptocci and Staphylococcus aureus. Curr. Topics Microbiol. Immunol. 174:1, 1991.
8. Bohach, G.A. & Schlievert, P.M. Conservation of the biologically active portions of staphylococcal enterotoxins C1 and C2. Infect. Immun. 57:2249, 1989.
9. 1 in Escherichia coli. Infect. Immun. 55:428, 1987.
10. Betley, M.J. & Mekalanos, J.J. Nucleotide sequence of the type A staphylococcal enterotoxin gene. J. Bacteriol. 170:34, 1988.
11. Betley, M.J. & Mekalanos, J.J. Staphylococcal enterotoxin A is encoded by phage. Science 229:185, 1985.
12. Betley, M.J., Lofdahl, S., Kreiswirth, B.N., et al. Staphylococcal enterotoxin A gene is associated with a variable genetic element. Proc. Natl. Acad. Sci. USA 81:5179, 1984.
13. Borst, D.W. & Betley, M.J. Phage-associated differences in staphylococcal enterotoxin A gene (sea) expression correlate with sea allele class. Infect. Immun. 62:113, 1994.
14. Tepper, R.I. & Mulé, J.J. Experimental and clinical studies of cytokine gene-modified tumor cells. Hum. Gene Then 5:153, 1994.
15. Krauss, J.C., Strome, S.E., Chang, A.E., et al. Enhancement of immune reactivity in the lymph nodes draining a murine melanoma engineered to elaborate interleukin-4. J. Immunother. 16:77, 1994.
16. Area, M.J., Krauss, J.C., Atsushi, A., et al. Therapeutic efficacy of T cells derived from lymph nodes draining a poorly immunogenic tumor transduced to secrete granulocyte-macrophage colony-stimulating factor. Cancer Gene Ther. 2:1, 1996.
17. Shu, S., Krinock, R.A., Matsumura, T., et al. Stimulation of tumor-draining lymph node cells with superantigenic staphylococcal toxins leads to the generation of tumor-specific effector T cells. J. Immunol. 152:1277, 1994.
18. Inoue, M., Plautz, G.E. & Shu, S. Treatment of intracranial tumors by systemic transfer of superantigen-activated tumor-draining lymph node T cells. Cancer Res. 46:4702, 1996.
19. Dranoff, G., Jaffee, E., Lazenby A., et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting antit-tumor immunity. Proc. Natl. Acad. Sci. USA 90:3539, 1993.
20. Krauss, J.C., Mayo-Bond, L.A., Rogers, C.E., et al. An in vivo animal model of gene therapy for leukocyte adhesion deficiency. J. Clin. Invest. 88:1412, 1991.
21. Ho, S.N., Hunt, H.D., Horton, R.M., et al. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51, 1989.
22. Danos, O. & Mulligan, R.C. Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. Proc. Natl. Acad. Sci. USA 86:6460, 1988.
23. Sanbrook, J., Fritsch, E.F. & Maniatis, T. Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989.
24. Harlow E. & Lane D. Antibodies: A Laboratory Manual. Cold Spring Harbor Press, Cold Spring Harbor, NY, 1988.
25. Bill, J., Kanagawa, O., Woodland, D.L. & Palmer, E. The MHC molecule I-E is necessary but not sufficient for the clonal deletion of V beta 11-bearing T cells. J. Exp. Med. 169:1405, 1989.
26. Haskins, K., Hannum, C., White, J., et al. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J. Exp. Med. 160:452, 1984.
27. Pecceu, F., Dousset, P., Shire, D., et al. Human interleukin 1β fused to the human growth hormone signal peptide is N-glycosylated and secreted by Chinese hamster ovary cells. Gene 97:253, 1991.
28. Krauss, J.C., Cameron, M.J., Park, A.N., et al. Efficient transduction of early passage human melanoma to secrete IL-4. J. Immunol. Meth. 183:239, 1994.
29. Coley, W.B. The treatment of inoperable sarcoma by bacterial toxins (the mixed toxins of the Streptococcus erysipelas and the Bacillus prodigiosus). Proc. R. Soc. Med. 3:1, 1909-1910.
30. Carswell, E.A., Old, L.J., Kassel, R.L., et al. An endotoxin-induced serum factor that causes necrosis of tumors. Proc. Natl. Acad. Sci. USA 72:3666, 1975.
31. Herman, A., Kappler, J.W., Marrack P., et al. Superantigens: Mechanism of T-cell stimulation and role in immune responses. Annu. Rev. Immunol. 9:745, 1991.
32. Marrack, P., Blackman, M., Kushnir, E., et al. The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells. J. Exp. Med. 171:455, 1990.
33. McCormack, J.E., Kappler, J. & Marrack, P. Stimulation with specific antigen can block superantigen-mediated deletion of T cells in vivo. Proc. Natl. Acad. Sci. USA 91:2086, 1994.
34. Newell, K.A., Ellenhom, J.D.I., Bruce, D.S., et al. In vivo T-cell activation by staphylococcal enterotoxin B prevents outgrowth of a malignant tumor. Proc. Natl. Acad. Sci. USA 88:1074, 1991.
35. Yoshizawa, H., Chang, A.E. & Shu, S. Specific adoptive immunotherapy mediated by tumor-draining lymph node cells sequentially activated with anti-CD3 and IL-2. J. Immunol. 147:729, 1991.