HLA-DR 52- and 51-associated DRB1 alleles in Kenya, East Africa

Tissue Antigens

Volumn 49, Issue 4, 1997, Pages 397-402

  Dunand, V A ^a,c   Ng, C M ^b   Wade, J A ^b,c   Bwayo, J ^e   Plummer, F A ^d,e   MacDonald, K S ^a,c,e,f  

^a Pediatric Oral and Maxillofacial Surgery   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF MANITOBA   (Canada)

^e UNIVERSITY OF NAIROBI   (Kenya)

^f MOUNT SINAI HOSPITAL   (Canada)

Author keywords

DR51 allele; DR52 allele; East Africa; Genetic diversity; HLA DR; Kenya; PCR; Population genetics; SSOP

Indexed keywords

HLA DR ANTIGEN; HLA DR51 ANTIGEN; HLA DR52 ANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; BIODIVERSITY; DNA DETERMINATION; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC POLYMORPHISM; HLA TYPING; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; KENYA; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PRIORITY JOURNAL; SEROLOGY; SINGLE STRAND CONFORMATION POLYMORPHISM;

GENETTA;

EID: 0030897448     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0039.1997.tb02768.x     Document Type: Article

References (19)

1. Excoffier L, Pellegtini B, Sanchez-Mazas A, Simon C, Langaney A. Genetics and history of sub-Saharan Africa. Yrbk Phys Anthropol 1987: 30: 151-94.
2. Hill AVS, Allsopp CEM, Kwiatkowski D et al. Extensive genetic diversity in the HLA class II region of Africans, with focally predominant allele, DRB 1*1304. Proc Natl Acad Sci U S A 1992: 89: 2277-81.
3. Olerup O, Troye-Blomberg M, Schreuder GMT, Riley EM. HLA-DR and -DQ gene polymorphism in West Africans is twice as extensive as in North European Caucasians: evolutionary implications. Proc Natl Acad Sci U S A 1991: 88: 8480-84.
4. du Toit ED, MacGregor KJ, Taljaard DG, Oudshoorn M. HLA-A, B, C, DR and DQ polymorphisms in three South African population groups: South African Negroes, Cape Coloureds and South African Caucasoids. Tissue Antigens 1987: 31: 109-125.
5. du Toit ED, Taljaard DG, Marshall J, Ritchie C, Oudshoorn M. The HLA genetic constitution of the Bushmen (San). Hum Immunol 1990: 28: 406-15.
6. Shaffer AL, Falk-Wade JA, Tortorelli V et al. HLA-DRw52-associated DRB1 alleles: Identification using polymerase chain reaction-amplified DNA, sequence-specific oligonucleotide probes, and a chemilumimnescent detection system. Tissue Antigens 1992: 39: 84-90.
7. Ginsberg C, Quakyi I, Mshana R, Ngogang J and Johnson A. HLA-DR profiles in Cameroon and Ivory Coast. 22nd annual ASHI Meeting Abstracts. Hum Immunol 1996: 49(suppl 1): 48.
8. Lee TD, Lee A, Shi WX. HLA-A, -B, -DR, -DQ antigens in black North Americans. Tissue Antigens 1991: 37: 79-83.
9. Gustincich S, Manfioletti G, Del Sal G, Schneider C, Carninci P. A fast method for high-quality genomic DNA extraction from whole human blood. BioTechniques 1991: 11: 298-302.
10. Wade JA, Hurley CK, Hastings A, et al. Combinatorial diversity in DR2 haplotypes. Tissue Antigens 1993: 41: 113-18.
11. Riley E and Olerup O. HLA polymorphism and evolution. Immunol Today 1992: 13: 333-35.
12. Dard P, Sanchez-Mazas A, Tiercy J-M et al. HLA-A, -B, and -DR differentiation among North and West African populations. In: Tsuji K, Aizana M, Sasazuki T, ed. HLA 1991, vol. 1. Oxford: Oxford Science Publications, 1992: 632-36.
13. Hammond MG, du Toit ED, Sachs JA, Kaplan C, Mbayo K. HLA in southern African populations. In: Tsuji K, Aizana M, Sasazuki T, ed. HLA 1991, vol. 1. Oxford: Oxford Science Publications, 1992: 636-38.
14. Stastny P, Kalil J. HLA in North American and South American Negroids. In: Tsuji K, Aizana M, Sasazuki T, ed. HLA 1991. vol. 1. Oxford: Oxford Science Publications, 1992: 638-40.
15. Allsopp CEM, Harding RM, Taylor C et al. Interethnic geneue differentiation in Africa: HLA class I antigens in the Gambia. Am J Hum Genet 1992: 50: 411-21.
16. Excoftier L, Harding R, Sokal RR, Pellegrini B, Sanchez-Mazas A. Spatial differentiation of RH and GM haplotype frequencies in Sub-Saharan Africa and its relation to linguistic affinities. Hum Biol 1991: 63: 273-307.
17. Blanc M, Sanchez-Mazas A, Van Blyenburgh NH, Sevin A, Pison G, Langaney A. Interethnic genetic differentiation: GM polymorphism in Eastern Senegal. Am J Hum Genet 1990: 46: 383-92.
18. Hughes AL, Nei M. Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals over-dominant selection. Nature 1988: 335: 167-70.
19. Hill AVS, Allsopp CEM, Kwiatkowski D et al. Common West African HLA antigens are associated with protection from severe malaria. Nature 1991: 352: 595-600.