Bone acidic glycoprotein-75 self-associates to form macromolecular complexes in vitro and in vivo with the potential to sequester phosphate ions

Journal of Cellular Biochemistry

Volumn 64, Issue 4, 1997, Pages 547-564

  Gorski, Jeffrey P ^a   Kremer, Edward A ^a   Chen, Yan ^a   Ryan, Steve ^a   Fullenkamp, Colleen ^a   Delviscio, John ^a   Jensen, Karen ^b   McKee, Marc D ^c  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

aggregation dependent neoepitope; bone acidic glycoprotein 75; macromolecular complexes in vivo and in vitro; self association; sequestration of phosphate ions

Indexed keywords

GLYCOPROTEIN; GLYCOPROTEIN 75; MONOCLONAL ANTIBODY; OSTEOPONTIN; PHOSPHATE; SIALOPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL ULTRASTRUCTURE; CONTROLLED STUDY; MALE; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NEWBORN; NONHUMAN; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PURIFICATION; RAT;

ANIMALS; BONE AND BONES; CRYSTALLIZATION; DIMERIZATION; EPITOPES; GLYCOPROTEINS; MACROMOLECULAR SUBSTANCES; MICROSCOPY, ELECTRON; PHOSPHATES; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030897351     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19970315)64:4<547::AID-JCB3>3.0.CO;2-R     Document Type: Article

References (53)

1. Aeschlimann D, Wetterwald A, Fleisch H, Paulsson M (1993): Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes. J Cell Biol 120:1461-1470.
2. Arias AL, Fernandez MS, Dennis JE, Caplan AI (1991): Collagens of the chicken eggshell membranes. Connect Tissue Res 26:37-45.
3. Barlett GR (1959): Phosphorus assay in column chromatography. J Biol Chem 234:466-468.
4. Baron R (1993): Anatomy and Ultrastructure of Bone. In Favus MJ (ed): "Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism." New York: Raven Press, pp 3-9.
5. Bendayan M (1989): Protein A-gold and protein G-gold postembedding immunoelectron microscopy. In Hayat MA (ed): "Colloidal Gold: Principles, Methods, and Applications," Vol 1. New York: Academic Press, pp 33-94.
6. Beninati S, Senger DR, Cordella Miele E, Mukherjee AB, Chackalaparampil I, Shanmugam V, Singh K, Mukherjee BB (1994): Osteopontin: Its tranglutaminase-catalyzed posttranslational modifications and cross-linking to fibronectin. J Biochem 115:675-682.
7. Bianco P, Riminucci M, Silvestrini G, Bonucci E, Termine JD, Fisher LW, Gehron Robey P (1993): Localization of bone sialoprotein (BSP) to Golgi and post-Golgi secretory structures in osteoblasts and to discrete sites in early bone matrix. J Histochem Cytochem 41:193-203.
8. Bonucci E (1967): Fine structure of early cartilage calcification. J Ultrastruct Res 20:33-50.
9. Bonucci E, Silvestrini G, Di Grezia R (1988): The ultrastructure of the organic phase associated with the inorganic substance in calcified tissues. Clin Ortho Rel Res 233:243-261.
10. Boskey AL (1995): Osteopontin and related phosphorylated sialoproteins: Effects on mineralization. Ann N Y Acad Sci 760:249-256.
11. Boskey AL, Maresca M, Ullrich W, Doty SB, Butler WT, Prince CW (1993): Osteopontin-hydroxyapatite interactions in vitro: Inhibition of hydroxyapaptite formation and growth in a gelatin-gel. Bone Miner 22:147-159.
12. Bumol TF, Walker LE, Reisfeld RA (1984): Biosynthetic studies of proteoglycans in human melanoma cells with a monoclonal antibody to a core glycoprotein of chondroitin sulfate proteoglycans. J Biol Chem 259:12733-12741.
13. Chen Y, Bhajanit BS, Gorski JP (1992): Calcium and collagen binding properties of osteopontin, bone sialoprotein, and bone acidic glycoprotein-75 from bone. J Biol Chem 267:24871-24878.
14. Fazekas de St Groth S, Scheidegger D (1980): Production of monoclonal antibodies: strategy and tactics. J Immunol Methods 35:1-21.
15. Fisher LW, McBride OW, Termine JD, Young MF (1990): Human bone sialoprotein: Deduced protein sequence and chromosomal localization. J Biol Chem 265:2347-2351.
16. Gerstenfeld LC, Gotoh Y, McKee MD, Nanci A, Landis WJ, Glimcher MJ (1990): Expression and ultrastructural localization of a major 66 kDa phosphoprotein synthesized by chicken osteoblasts during in vitro mineralization. Anat Rec 228:93-103.
17. Glimcher MJ (1989): Mechanisms of calcification: Role of collagen fibrils and collagen-phosphoprotein complexes in vitro and in vivo. Anat Rec 224:139-153.
18. Gorski JP (1992): Acidic phosphoproteins from bone matrix: A structural rationalization of their role in biomineralization. Calcif Tissue Int 50:391-396.
19. Gorski JP, Shimizu K (1988): Isolation of new phosphorylated glycoprotein from mineralized phase of bone that exhibits limited homology to adhesive protein osteopontin. J Biol Chem 263:15938-15945.
20. Gorski JP, Griffin D, Dudley G, Stanford C, Thomas R, Huang C, Lai E, Karr B, Solursh M (1990): Bone acidic glycoprotein-75 is a major synthetic product of osteoblastic cells and localized as 75-and/or 50-kDa forms in mineralized phases of bone and growth plate and in serum. J Biol Chem 265:14956-14963.
21. Gorski JP, Kremer E, Ruiz-Perez J, Wise GE, Artigues A (1995): Conformational analyses on soluble and surface bound osteopontin. Ann N Y Acad Sci 760:12-23.
22. Gorski JP, Kremer E, Chen Y (1996): Bone acidic glycoprotein-75 self-associates to form large macromolecular complexes. Connect Tissue Res 35:136-144.
23. Gotoh Y, Pierschbacher MD, Grzesiak JJ, Gerstenfeld L, Glimcher MJ (1990): Comparison of two phosphoproteins in chicken bone and their similarities to the mammalian bone proteins, osteopontin and bone sialoprotein II. Biochem Biophys Res Commun 173:471-479.
24. Groot CG (1982): An electron microscopic examination for the presence of acid groups in the organic matrix of mineralization nodules in foetal bone. Metab Bone Dis Rel Res 4:77-84.
25. Helfrich MH, Nesbitt SA, Dorey EL, Horton MA (1992): Rat osteoclasts adhere to a wide range of RGD peptide-containing proteins, including the bone sialoproteins and fibronectin, via a beta-3 integrin. J Bone Miner Res 7:335-343.
26. Heinegard D, Oldberg A (1989): Structure and biology of cartilage and bone matrix noncollagenous macromolecules. FASEB J 3:2042-2051.
27. Hunter GK, Goldberg HA (1994): Modulation of crystal formation by bone phosphoproteins: role of glutamic acid-rich sequences in the nucleation of hydroxyapatite by bone sialoprotein. Biochem J 302:175-179.
28. Hunter GK, Holmyard DP, Pritzker KP (1993): Calcification of chick verbebral chondrocytes grown in agarose gels: A biochemical and ultrastructural study. J Cell Sci 104:1031-1038.
29. Hunter GK, Kyle CL, Goldberg HA (1994): Modulation of crystal formation by bone phosphoproteins: Structural specificity of the osteopontin-mediated inhibition of hydroxyapatite formation. Biochem J 300:723-728.
30. Ingram RT, Clarke BL, Fisher LW, Fitzpatrick LA (1993): Distribution of noncollagenous proteins in the matrix of adult human bone: Evidence of anatomic and functional heterogeneity. J Bone Miner Res 8:1019-1029.
31. Jee, WSS (1983): The skeletal tissues. In Weiss L (ed): "Histology: Cell and Tissue Biology." New York: Elsevier Biomedical, pp 200-255.
32. Lee KL, Aubin JE, Heersche JN (1992): Beta-glycerol phosphate induced mineralization of osteoid cells does not alter expression of extracellular matrix components in fetal rat calvarial cultures. J Bone Miner Res 7:1211-1219.
33. Lowenstam A, Weiner S (1989): Biomineralization processes. In: "On Biomineralization." London: Oxford University Press, pp 25-49.
34. Magnuson SK, Booth R, Porter S, Gorski JP (1997): Bilateral tibial marrow ablation induces a transient hypercalcemia arising from a wave of systemic bone resorption inhibitable with methylprednisolone or deflazacort. J Bone Miner Res 12.
35. McKee MD, Nanci A, Landis WJ, Gotoh Y, Gerstenfeld LC, Glimcher MJ (1990): Developmental appearance and ultrastructural immunolocalization of a major 66 kDa phosphoprotein in embryonic and post-natal chicken bone Anat Rec 228:77-92.
36. McKee MD, Nanci A (1993): Ultrastructural, cytochemical and immunocytochemical studies on bone and its interfaces. Cells Mater 3:219-243.
37. 2HS-glycoprotein) proteins in rat bone. J Bone Miner Res 8:485-496.
38. McKee MD, Nanci A (1995): Postembedding colloidal-gold immunocytochemistry of non-collagenous extracellular matrix proteins in mineralized tissues. Microsc Res Tech 31:44-62.
39. Mitrovic N, Dorries U, Schachner U (1994): Expression of the extracellular matrix glycoprotein tenascin in the somatosensory cortex of the mouse during postnatal development: An immunocytochemical and in situ hybridization analysis. J Neurocytol 23:364-378.
40. Oldberg A, Franzen A, Heinegard D (1986): Cloning and sequence analysis of a rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell binding sequence. Proc Natl Acad Sci U S A 83:8819-8823.
41. Oldberg A, Franzen A, Heinegard D (1988a): The primary structure of a cell-binding bone sialoprotein. J Biol Chem 263:19430-19432.
42. Oldberg A, Franzen A, Heinegard D, Pierschbacher M, Ruoslahti E (1988b): Identification of a bone sialoprotein receptor in osteosarcoma cells. J Biol Chem 263:19433-19436.
43. 2+-binding capacity of canine cortical bone extracts. Am J Physiol 255:H101-H110.
44. Prince CW, Dickie D, Krumdieck CL (1991): Osteopontin, a substrate for transglutaminase and factor XIII activity. Biochem Biophys Res Commun 177:1205-1210.
45. Ritter MN, Farach-Carson MC, Butler WT (1992): Evidence for the formation of a complex between osteopontin and osteocalcin. J Bone Miner Res 7:877-885.
46. 3 potentiate bone resorption. J Biol Chem 268:9901-9907.
47. Sato, M. Grasser W, Harms S, Fullenkamp C, Gorski JP (1992): Bone acidic glycoprotein-75 inhibits resorption activity of isolated rat and chicken osteoclasts. FASEB J 6:2966-2976
48. Solursh M, Meier S (1972): The requirement for RNA synthesis in the differentiation of cultured chick chrondocytes. J Exp Zool 181:253-262.
49. Somerman MJ, Fisher LW, Foster RA, Sauk JJ (1988): Human bone sialoprotein I and II enhance fibroblast attachment in vitro. Calcif Tissue Int 43:50-53.
50. Sorensen ES, Rasmussen LK, Moller L, Jensen PH, Hojrup P, Petersen TE (1994): Localization of transglutaminase-reactive glutamine residues in bovine osteopontin. Biochem J 304:13-16.
51. Takagi M, Parmley RT, Toda Y, Denys FR (1983): Ultrastructural cytochemistry of complex carbohydrates in osteoblasts, osteoid, and bone matrix. Calcif Tissue Int 35:309-319.
52. Weiner S, Traub W (1992): Bone structure: From angstroms to microns. FASEB J 6:879-885.
53. Zhang Q, Domenicucci C, Goldberg H, Wrana JL, Sodek J (1990): Characterization of fetal porcine bone sialoproteins, secreted phosphoprotein I (SPP1, osteopontin), bone sialoprotein, and a 23 kDa glycoprotein. J BiolChem 265:7583-7589.