Aldose reductase as dihydrodiol dehydrogenase: Naphthoquinone formation by rat lens aldose reductase

Advances in Experimental Medicine and Biology

Volumn 414, Issue , 1997, Pages 499-505

  Sato, Sanai ^a   Sugiyama, Katsumi ^a   Carper, Deborah ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; DIHYDRODIOL DEHYDROGENASE; IMIRESTAT; NAPHTHOQUINONE; PONALRESTAT; SORBINIL; TOLRESTAT;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; CATARACTOGENESIS; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME INHIBITOR INTERACTION; ENZYME METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LENS; NONHUMAN; PRIORITY JOURNAL; RAT; SPECTRAL SENSITIVITY;

EID: 0030897253     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (14)

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2. Hara, A., Nakayama, T., Harada, T., Kanazu, T., Shinoda, M., Deyashiki, Y., and Sawada, H.: Distribution and characterization of dihydrodiol dehydrogenases in mammalian ocular tissues. Biochem. J.275 (1991) 113-119.
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8. Sato, S.: Aldose reductase the major protein associated with naphthalene dihydrodiol dehydrogenase activity in rat lens. Invest. Ophthalmol. Vis. Sci. 34 (1993) 3172-3178.
9. Smithgall, T.E., Harvey, R.G., and Penning, T.M.: Spectroscopic identification of ortho-quinones as the products of polycyclic aromatic trans-dihydrodiol oxidation catalyzed by dihydrodiol dehydrogenase. A potential route of proximate carcinogen metabolism. J. Biol. Chem. 263 (1988) 1814-1820.
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