Protection against light-induced retinal degeneration with naftidrofuryl (praxilene) in the rat

Journal of Ocular Pharmacology and Therapeutics

Volumn 13, Issue 1, 1997, Pages 89-94

  Safars, M ^a   Jeanny, J C ^a   Mosnier, M ^b   Courtois, Y ^a  

^a INSERM   (France)

^b Division Oberval   (France)

Author keywords

[No Author keywords available]

Indexed keywords

NAFTIDROFURYL OXALATE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ILLUMINATION; INTRAPERITONEAL DRUG ADMINISTRATION; LIGHT EXPOSURE; MALE; NONHUMAN; PHOTORECEPTOR; RAT; RETINA DEGENERATION;

EID: 0030896809     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.1997.13.89     Document Type: Article

References (14)

1. Hauw, J.J., Boutry, J.M., Guillermin, A.M., Barbe, P., and Boissonnet, P. Un nouveau promoteur de croissance nerveuse: le Naftidrofuryl. C.R. Acad. Sci. 14:543-548, 1986.
2. Louis, J.C. Effect of Naftidrofuryl on metabolism and survival of cultured neurons. Neurochem. Res. 14:1195-1201, 1989.
3. Lefebvre, P., Sraecker, H., Moonen, G., and Van De Water, T. Naftidrofuryl affects neurite regeneration by injured adult auditory neurons. Acta Otolaryngol. 113:498-501, 1993.
4. Mermoud, A. and Faggioni, R. Le traitement du glaucome a pression normale avec un antagoniste des recepteurs S2 de la serotonine, le Naftidrofuryl (Praxilene). Klin. Mbl. Augenheilk 198:332-334, 1991.
5. Faktorovitch, E.G., Steinberg, R.G., and Yasumura, D. Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor. Nature 347:83-86, 1990.
6. Faktorovitch, E.G., Steinberg, R.G., and Yasumura, D. Basic fibroblast growth factor and local injury protect photoreceptors from light damage in the rat. J. Neurosci. 12:3554-3567, 1992.
7. LaVail, M.M., Unoki, K., Yasumura, D., and Matthes, M.T. Multiple growth factors, cytokines and neurotrophins rescue photoreceptors from the damaging effects of constant light. Proc. Natl. Acad. Sci. US.A. 89:11249-11253, 1993.
8. Hicks, D., Malecaze, F., Mascarelli, F., Bugra, K., and Courtois, Y. Retinal degeneration: Fibroblast growth factor and photoreceptor-pigmented epithelium cell biology. Anderson, Hollyfield, and Lavail, eds, Plenum Press, 1991, pp. 87-99.
9. Organisciak, D.T., Darrow, R.M., Bicknell, I.R., Liang, Y.L., Pickford, M., and Blanks, J.C. Protection against retinal light damage by natural and synthetic antioxidants In Retinal Degenerations, Anderson, R.E., Hollyfield, J.G., and La Vail, M.M. eds., Boca Raton, Fla: CRC Press, Inc., 1991, pp. 189-201.
10. Szabo, M.E., Droy-Lefaix, M.T., Doly, M., and Braquet, P. Free radical-mediated effects in reperfusion injury: a histologic study with Superoxide dismutase and EGB 761 in rat retina. Ophthalmic Res. 23:225-234, 1991.
11. Goureau, O., Jeanny, J.C., Becquet, F., Hartmann, M.P., and Courtois, Y. Protection against light-induced retinal degeneration by an inhibitor of NO synthase. Neuroreport 5:223-236,1993.
12. Goureau, O., Hicks, D., and Courtois Y. Production of nitric oxide by human retinal pigmented epithelial cells in response to cytokines. Biochem. Biophys. Res. Comm. 1:120-126, 1994.
13. Reme, C.E., Braschler, U.F., Roberts, J., and Dillon, J. Light damage in the rat retina: Effect of a radioprotective agent (WR-77913) on acute rod outer segment disk disruptions. Photochem. Photobiol. 54:137-142, 1991.
14. C receptors in rat retinal bipolar cells by protein kinase C. J. Physiol. (London) 481:325-330, 1994.