Treatment of oropharyngeal candidiasis in immunocompetent infants: A randomized multicenter study of miconazole gel vs. nystatin suspension

Pediatric Infectious Disease Journal

Volumn 16, Issue 3, 1997, Pages 288-293

  Hoppe, Jörg E ^a   Burr, R ^b   Ebeling, H ^b   Hirschbrunn, P ^b   Hoepner, H ^b   Holder, H ^b   Holzgraefe, E ^b   Kneppo, K ^b   Koch, F ^b   Lange, H ^b   Langer, M ^b   Mangelsdorf Taxis, R ^b   Maurer, L ^b   Moll, E ^b   Preuss, G ^b   Renz, A ^b   Rossius, H ^b   Sandbrink, H ^b   Schlunk, P ^b   Schmidt Riese, U ^b   Scholz, H P ^b   Schoyerer, R ^b   Steinki, J ^b   Tjhen, K Y ^b   Van De Kamp, B ^b   Wartha, R ^b   Zimmer, J ^b   more..

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b NONE

Author keywords

Candida albicans; Candidiasis; miconazole; nystatin

Indexed keywords

INFECTOSOOR; MICONAZOLE; NYSTATIN; TROPFEN; UNCLASSIFIED DRUG;

ARTICLE; CANDIDA; CANDIDA ALBICANS; CANDIDA PARAPSILOSIS; CANDIDIASIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG EFFICACY; DRUG SAFETY; DRUG SCREENING; FEMALE; HUMAN; IMMUNOCOMPETENCE; INFANT; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PATIENT COMPLIANCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RELAPSE; THRUSH; VOMITING;

ANTIFUNGAL AGENTS; CANDIDIASIS, ORAL; FEMALE; GELS; HUMANS; IMMUNOCOMPETENCE; INFANT; MALE; MICONAZOLE; NYSTATIN; PROSPECTIVE STUDIES; SUSPENSIONS;

EID: 0030896755     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006454-199703000-00007     Document Type: Article

References (23)

1. Kozinn PJ, Taschdjian CL, Dragutsky D, Minsky A. Therapy of oral thrush: a comparative evaluation of gentian violet, mycostatin, and amphotericin B. In: Monographs on therapy, vol 2. New Brunswick, NJ: Squibb Institute for Medical Research, 1957:16-24.
2. Flynn PM, Cunningham CK, Kerkering T, et al. Oropharyngeal candidiasis in immunocompromised children: a randomized, multicenter study of orally administered fluconazole suspension versus nystatin. J Pediatr 1995;127:322-8.
3. Mansour A, Gelfand EW. A new approach to the use of antifungal agents in infants with persistent oral candidiasis. J Pediatr 1981;98:161-2.
4. Hughes WT. Candidiasis. In: Feigin RD, Cherry JD, eds. Textbook of pediatric infectious diseases. 3rd ed. Philadelphia: Saunders, 1992:1907-16.
5. Buchner SJ. Persistent thrush in young infants [Letter]. Pediatr Infect Dis J 1987;6:1074.
6. Boon JMM, Lafeber HN, t'Mannetje AH, et al. Comparison of ketoconazole suspension and nystatin in the treatment of newborns and infants with oral candidosis. Mycoses 1989;32: 312-5.
7. Grossman ER. Treatment of thrush [Letter]. Pediatr Infect Dis J 1988;7:303.
8. Van Cutsem JM, Thienpont D. Miconazole, a broad-spectrum antimycotic agent with antibacterial activity. Chemotherapy 1972;17:392-404.
9. Holmberg K. Oral mycoses and antifungal agents. Swed Dent J 1980;4:53-61.
10. Botter AA. Miconazole gel for the treatment of oral thrush in adult patients. Mykosen 1980;23:574-9.
11. Casneuf J, de Loore F, Dhondt F, et al. Oral thrush in children treated with miconazole gel. Mykosen 1980;23:75-8.
12. Reading JH, Clifford PD, Coles RW, Rajagopalan N. An open assessment of miconazole oral gel in the treatment of paediatric oral candidosis in general practice. Curr Ther Res 1981;30:605-10.
13. Hoppe JE, Moosmann K. Vergleich von Miconazol-Gel und Nystatin-Hydroxyethylcellulose-Gel zur Behandlung des Mundsoors bei Säuglingen. Monatsschr Kinderheilkd 1994;142:285-7.
14. Hoppe JE, Hahn H, Antimycotics Study Group. Randomized comparison of two nystatin oral gels with miconazole oral gel for treatment of oral thrush in infants. Infection 1996;24:136-9.
15. Schaad UB, Bachmann D. Prospektiver Vergleich von Miconazol-Gel und Nystatin-Suspension in der Therapie des Mundsoors. Schweiz Med Wochenschr 1983;113:1356-62.
16. Freitag V, Schumacher G, Sternowsky HJ. Soor im Mundund Windelbereich: Behandlung mit Miconazol oder Nystatin. Kinderarzt 1983;14:177-8.
17. Rousselle P, Freydiere A, Couillerot PJ, de Montclos H, Gille Y. Rapid identification of Candida albicans by using Albicans ID and Fluoroplate agar plates. J Clin Microbiol 1994;32: 3034-6.
18. Mintz AA, Tengg NE. The management of oral moniliasis (thrush) in a pediatric clinic. Clin Med 1965;72:992-1000.
19. Wainer S, Cooper PA, Funk E, Bental RY, Sandler DA, Patel J. Prophylactic miconazole oral gel for the prevention of neonatal fungal rectal colonization and systemic infection. Pediatr Infect Dis J 1992;11:713-6.
20. Roed-Petersen B. Miconazole in the treatment of oral candidosis. Int J Oral Surg 1978;7:558-63.
21. Goodman Gilman A, Goodman LS, Gilman A. The pharmacological basis of therapeutics. 6th ed. New York: MacMillan, 1980:1232-3.
22. Schwarze R, Blaschke-Hellmessen R, Pappisch M. Orale Applikation von Nystatin und Amphotericin B zur Prophylaxe und Therapie von Candidamykosen bei Risikoneugeborenen. In: Sitzmann FC (ed.) Infektionen mit Parasiten und Pilzen im Kindesalter, Munich: H. Marseille, 1995:199-210.
23. Dhondt F, Ninane J, de Beule K, Dhondt A, Cauwenbergh G. Oral candidosis: treatment with absorbable and non-absorbable antifungal agents in children. Mycoses 1992;35:1-8.