Characterisation of γδ T cells in renal cell carcinoma patients by polymerase chain reaction analysis of T cell receptor transcripts

Cancer Immunology Immunotherapy

Volumn 44, Issue 1, 1997, Pages 27-34

  Olive, Colleen ^a   Nicol, David ^a   Falk, Michael C ^a  

^a PRINCESS ALEXANDRA HOSPITAL   (Australia)

Author keywords

T cell receptor transcripts; polymerase chain reaction; renal cell carcinoma; tumour infiltrating lymphocytes

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; KIDNEY CARCINOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOUTHERN BLOTTING; TUMOR ASSOCIATED LEUKOCYTE; TUMOR IMMUNITY;

CARCINOMA, RENAL CELL; HUMANS; KIDNEY NEOPLASMS; POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RNA, MESSENGER; T-LYMPHOCYTE SUBSETS;

EID: 0030896573     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050351     Document Type: Article

References (36)

1. Alam SM, Clark SJ, Leech V, Whitford P, George WD, Campbell AM (1992) T cell receptor γ/δ expression on lymphocyte populations of breast cancer patients. Immunol Lett 31:279
2. Alexander J, Rayman P, Edinger M, Connelly R, Tubbs R, Bukowski R, Pontes E, Finke J (1990) TIL from renal-cell carcinoma: restimulation with tumour influences proliferation and cytolytic activity. Int J Cancer 45:119
3. Alexander JP, Kudoh S, Melsop KA, Hamilton TA, Edinger MG, Tubbs RR, Sica D, Tuason L, Klein E, Bukowski RM, Finke JH (1993) T-cells infiltrating renal cell carcinoma display a poor proliferative response even though they can produce interleukin 2 and express interleukin 2 receptors. Cancer Res 53:1380
4. Bernhard H, Jager E, Maeurer MJ, Meyer zum Buschenfelde KH, Knuth A (1996) Tumour associated antigens in human renal cell carcinoma: MHC restricted recognition by cytotoxic T lymphocytes. Tissue Antigens 48:22
5. Born W, Happ MP, Dallas A, Reardon C, Kubo R, Shinnick T, Brennan P, O'Brien R (1990) Recognition of heat shock proteins and γδ cell function. Immunol Today 11:40
6. + activity. Microb Pathog 13:447
7. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156
8. Choudhary A, Davodeau F, Moreau A, Peyrat M-A, Bonneville M, Jotereau F (1995) Selective lysis of autologous tumor cells by recurrent γδ tumor-infiltrating lymphocytes from renal carcinoma. J Immunol 154:3932
9. DeKernion, Rammig K, Smith R (1978) The natural history of metastatic renal cell carcinoma: a computer analysis. J Urol 120:148
10. Falk MC, Ng G, Zhang GY, Fanning GC, Kamath KR, Knight JF (1994) Predominance of T-cell receptor Vδ3 in small bowel biopsies from coeliac disease patients. Clin Exp Immunol 98:78
11. Ferrarini M, Pupa SM, Zocchi MR, Rugarli C, Menard S (1994) Distinct pattern of HSP72 and monomeric laminin receptor expression in human lung cancers infiltrated by γ/δ T lymphocytes. Int J Cancer 57:486
12. Filgueira L, Zuber M, Merlo A, Harder F, Heberer M, Spagnoli GC (1993) Effects of different culture protocols on the expression of discrete T-cell receptor variable regions in human tumour infiltrating lymphocytes. Eur J Cancer 12:1754
13. + T cell line. J Immunother 10:1
14. Fujimoto S, Greene MI, Sehon AH (1976) Regulation of the immune response to tumor antigens II. The nature of immunosuppressor cells in tumor-bearing hosts. J Immunol 116:800
15. + αβ cells in the lamina propria but proliferation (Ki-67) of αβ and γδ cells in the epithelium. Eur J Immunol 23:505
16. Kabawat S, Bast RC, Welch WR, Knapp RC, Bhan AK (1983) Expression of major histocompatibility antigens and nature of inflammatory cellular infiltrate in ovarian neoplasms. Int J Cancer 32:547
17. Kaufmann SHE, Biu C, Yamamoto S (1993) Crosstalk between α/β T cells and γ/δ T cells in vivo: activation of α/β T cell responses alter γ/δ T cell modulation with the monoclonal antibody GL3. Proc Natl Acad Sci USA 90:9620
18. Kim HT, Nelson EL, Clayberger C, Sanjanwala M, Sklar J, Krensky AM (1995) γδ T cell recognition of tumour Ig peptide. J Immunol 154:1614
19. Kitayama J, Atomi Y, Nagawa H, Kuroda A, Mutoh T, Minami M, Juji T (1993) Functional analysis of TCR γδ cells in tumour-infiltrating lymphocytes (TIL) of human pancreatic cancer. Clin Exp Immunol 93:442
20. Koo AS, Tso CL, Shimabukuro T, Peyret C, Dekernion JB, Belldegrun A (1991) Autologous tumor-specific cytotoxicity of tumor-infiltrating lymphoctes derived from human renal cell carcinoma. J Immunother 10:347
21. Kowalczyk D, Skorupski W, Drews M, Nowak J (1994) Different pattern of T cell receptor δ gene rearrangement in tumour-infiltrating lymphocytes and peripheral blood in patients with solid tumours. Cancer Immunol Immunother 39:275
22. Mahvi DM, Carper SW, Storm EK, Teal SR, Sondel PM (1993) Overexpression of 27-kDa heat-shock protein in MCF-7 breast cancer cells: effects on lymphocyte-mediated killing by natural killer and γδ T cells. Cancer Immunol Immunother 37:181
23. Mancilla-Jimenez R (1976) Papillary renal cell carcinoma: a clinical, radiologic and pathologic study of 34 cases. Cancer 38:2469
24. McMenamin C, McKersey M, Kuhnlein P, Hunig T, Holt PG (1995) γδ T cells down-regulate primary IgE responses in rats to inhaled soluble protein antigens. J Immunol 154:4390
25. Mitropoulos D, Kooi S, Rodriguez-Villanueva J, Platsoucas CD (1994) Characterization of fresh (uncultured) tumour-infiltrating lymphocytes (TIL) and TIL-derived T cell lines from patients with renal cell carcinoma. Clin Exp Immunol 97:321
26. Olive C, Gatenby PA, Serjeantson SW (1992) Variable gene usage of T cell receptor γ- and δ-chain transcripts expressed in synovia and peripheral blood of patients with rheumatoid arthritis. Clin Exp Immunol 87:172
27. Pierce WC, Belldegrun A, Figlin RA (1995) Cellular therapy: scientific rationale and clinical results in the treatment of metastatic renal-cell carcinoma. Semin Oncol 22:74
28. Raulet D (1989) The structure, function, and molecular genetics of the γ/δ T cell receptor. Annu Rev Immunol 7:175
29. Schendel DJ, Gansbacher B, Oberneder R, Kriegmair M, Hofstetter A, Riethmuller G, Segurado OG (1993) Tumor-specific lysis of human renal cell carcinomas by tumor-infiltrating lymphocytes. I. HLA-A2-restricted recognition of autologous and allogeneic tumor lines. J Immunol 151:4209
30. Selin LK, Stewart S, Shen C, Mao HQ, Wilkins JA (1992) Reactivity of γδ T cells induced by the tumour cell line RPMI 8226: functional heterogeneity of clonal populations and role of GroEL heat shock proteins. Scand J Immunol 36:107
31. Seo N, Egawa K (1995) Suppression of cytotoxic T lymphocyte activity by γ/δ cells in tumour-bearing mice. Cancer Immunol Immunother 40:358
32. Tada T, Ohzeki S, Utsumi K, Takluchi H, Muramatsu M, Li X-F, Shimizu J, Fujiwara H, Hamaoka T (1991) Transforming growth factor-β-induced inhibition of T cell function: susceptibility difference in T cells of various phenotypes and functions and its relevance to immunosuppression in tumor bearing state. J Immunol 146:1077
33. + T cells by B7-transfected melanoma cells. Science 259:368
34. + T cells into human colorectal cancer: flow cytometric analysis of TCR-γδ expression in tumour-infiltrating lymphocytes. Clin Exp Immunol 102:167
35. Webb S, Morris C, Sprent J (1990) Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell 63:1249
36. Zocchi MR, Ferrarini M, Migone N, Casorati G (1994) T-cell receptor V delta gene usage by tumour reactive γδ T lymphocytes infiltrating human lung cancer. Immunology 81:234