Completion of the Saccharomyces cerevisiae genome sequence allows identification of KTR5, KTR6 and KTR7 and definition of the nine-membered KRE2/MNT1 mannosyltransferase gene family in this organism

Yeast

Volumn 13, Issue 3, 1997, Pages 267-274

  Lussier, Marc ^a   Sdicu, Anne Marie ^a   Winnett, Elaine ^a   Vo, Dahn H ^a   Sheraton, Jane ^a   Düsterhöft, Andreas ^b   Storms, Reginald K ^c   Bussey, Howard ^a  

^a MCGILL UNIVERSITY   (Canada)

^b QIAGEN GMBH   (Germany)

^c Gina Cody School of Engineering and Computer Science   (Canada)

Author keywords

cell wall; gene family; mannosyltransferase; protein glycosylation

Indexed keywords

MANNOSYLTRANSFERASE;

ARTICLE; CELL WALL; CHROMOSOME 14; CONTROLLED STUDY; DNA SEQUENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; SACCHAROMYCES CEREVISIAE;

AMINO ACID SEQUENCE; CELL WALL; CHROMOSOMES, FUNGAL; CLONING, MOLECULAR; DNA, FUNGAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, FUNGAL; GENOME, FUNGAL; MANNOSYLTRANSFERASES; MOLECULAR SEQUENCE DATA; MYCOTOXINS; OPEN READING FRAMES; PHYLOGENY; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0030896248     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0061(19970315)13:3<267::AID-YEA72>3.0.CO;2-K     Document Type: Article

References (21)

1. Altschul, S. F., Miller, W., Myers, E. W. and Lipman, D. J. (1990). Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
2. Baudin, A., Ozier-Kalogeropoulos, O., Denouel, A., Lacroute, F. and Cullin, C. (1993). A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae. Nucl. Acids Res. 21, 3329-3330.
3. Brown, J. L., Roemer, T., Lussier, M., Sdicu, A.-M. and Bussey, H. (1994). The K1 killer toxin: molecular and genetic applications to secretion and cell surface assembly. In Johnston, J. R. (Ed.), Molecular Genetics of Yeast: A Practical Approach. IRL Press, Oxford University Press, UK, pp. 217-231.
4. Bussey, H. (1991). K1 killer toxin, a pore-forming protein from yeast. Mol. Microbiol. 5, 2339-2343.
5. Chalfie, M., Tu, Y., Euskirchen, G., Ward, W. W. and Prasher, D. C. (1994). Green fluorescent protein as a marker for gene expression. Science 263, 802-805.
6. Gietz, R. D., Schiestl, R. H., Willems, A. R. and Woods, R. A. (1995). Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure. Yeast 11, 355-360.
7. Häusler, A. and Robbins, P. W. (1992). Glycosylation in Saccharomyces cerevisiae: cloning and characterization of an α-1,2-mannosyltransferase structural gene. Glycobiology 2, 77-84.
8. Häusler, A., Ballou, L., Ballou, C. E. and Robbins, P. W. (1992). Yeast glycoprotein biosynthesis: MNT1 encodes an α-1,2-mannosyltransferase involved in O-glycosylation. Proc. Natl. Acad. Sci. USA 89, 6846-6850.
9. Herscovics, A. and Orlean, P. (1993). Glycoprotein biosynthesis in yeast. FASEB J. 7, 540-550.
10. Hill, K., Boone, C., Goebl, M., Puccia, R., Sdicu, A.-M. and Bussey, H. (1992). Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins. Genetics 130, 273-283.
11. Kleene, R. and Berger, E. G. (1993). The molecular and cell biology of glycosyltransferases. Biochim. Biophys. Acta 1154, 283-325.
12. Lussier, M., Camirand, A., Sdicu, A.-M. and Bussey, H. (1993). KTR2: a new member of the KRE2 mannosyltransferase gene family. Yeast 9, 1057-1063.
13. Lussier, M., Sdicu, A.-M., Ketela, T. and Bussey, H. (1995). Localization and targeting of the Saccharomyces cerevisiae Kre2p/Mnt1p α1,2-mannosyltransferase to a medial Golgi compartment. J. Cell Biol. 131, 913-927.
14. Lussier, M., Sdicu, A.-M., Camirand, A. and Bussey, H. (1996). Functional characterization of the YUR1, KTR1 and KTR2 genes as members of the KRE2/ MNT1 mannosyltransferase gene family. J. Biol. Chem. 271, 11001-11008.
15. Mallet, L., Bussereau, F. and Jacquet, M. (1994). Nucleotide sequence analysis of an 11·7 kb fragment of yeast chromosome II including BEM1, a new gene of the WD-40 repeat family and a new member of the KRE2/MNT1 family. Yeast 10, 819-831.
16. Nei, M. (1987). Molecular Evolutionary Genetics. Columbia University Press, New York, NY, pp. 293-298.
17. Pryer, N. K., Wuestehube, L. J. and Schekman, R. (1992). Vesicle-mediated protein sorting. Ann. Rev. Biochem. 61, 471-516.
18. Ram, A. F., Wolters, A., Ten Hoopen, R. and Klis, F. M. (1994). A new approach for isolating cell wall mutants in Saccharomyces cerevisiae by screening for hypersensitivity to calcofluor white. Yeast 10, 1019-1030.
19. Rothstein, R. (1991). Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol. 194, 281-301
20. Shaper, J. H. and Shaper, N. L. (1992). Enzymes associated with glycosylation. Curr. Opin. Struct Biol. 2, 701-709.
21. Wach, A., Brachat, A., Pohlmann, R. and Philippsen, P. (1994). New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast 10, 1793-1808.