-
1
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
-
The ACCP/SCCM Consensus Conference Committee: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992; 101: 1644-1655.
-
(1992)
Chest
, vol.101
, pp. 1644-1655
-
-
-
2
-
-
34447496569
-
Increase in National Hospital Discharge Survey rates for septicemia - United States
-
Centers for Disease Control. Increase in National Hospital Discharge Survey rates for septicemia - United States. MMWR Morb Mortal Wkly Rep 1990; 39: 909-912.
-
(1990)
MMWR Morb Mortal Wkly Rep
, vol.39
, pp. 909-912
-
-
-
3
-
-
0028893025
-
The natural history of the systemic inflammatory response syndrome (SIRS)
-
Rangel-Fausto MS, Pittet D, Costigan M, Hwang T, Davis CS et al.: The natural history of the systemic inflammatory response syndrome (SIRS). JAMA 1995; 273: 117-123.
-
(1995)
JAMA
, vol.273
, pp. 117-123
-
-
Rangel-Fausto, M.S.1
Pittet, D.2
Costigan, M.3
Hwang, T.4
Davis, C.S.5
-
4
-
-
0025303027
-
Septic shock in humans: Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy
-
Parillo JE: Septic shock in humans: advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy. Ann Intern Med 1990; 113: 227-242.
-
(1990)
Ann Intern Med
, vol.113
, pp. 227-242
-
-
Parillo, J.E.1
-
5
-
-
0023239471
-
Effects of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis
-
Veterans Administration Systemic Sepsis Cooperative Study Group: Effects of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis. N Engl J Med 1987; 317: 659-665.
-
(1987)
N Engl J Med
, vol.317
, pp. 659-665
-
-
-
6
-
-
0023252009
-
A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock
-
Bone RC, Fisher CJ, Clemmer TP, Slotman GJ, Metz GA et al.: A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock. N Engl J Med 1987; 317: 653-658.
-
(1987)
N Engl J Med
, vol.317
, pp. 653-658
-
-
Bone, R.C.1
Fisher, C.J.2
Clemmer, T.P.3
Slotman, G.J.4
Metz, G.A.5
-
7
-
-
0028239555
-
Recombinant human interleukin-1 receptor antagonist in the treatment of patients with sepsis syndrome
-
Fisher CJ, Dhainaut JF, Opal SM, Pribble JP, Balk RA et al.: Recombinant human interleukin-1 receptor antagonist in the treatment of patients with sepsis syndrome. JAMA 1994; 271: 1836-1843.
-
(1994)
JAMA
, vol.271
, pp. 1836-1843
-
-
Fisher, C.J.1
Dhainaut, J.F.2
Opal, S.M.3
Pribble, J.P.4
Balk, R.A.5
-
8
-
-
0027511893
-
Secular trends in the epidemiology of nosocomial fungal infections in the United States, 1980-1990
-
Beck-Sague CM, Jarvis WR, the National Nosocomial Infections Surveillance System: Secular trends in the epidemiology of nosocomial fungal infections in the United States, 1980-1990. J Infect Dis 1993; 167: 1247-1251.
-
(1993)
J Infect Dis
, vol.167
, pp. 1247-1251
-
-
Beck-Sague, C.M.1
Jarvis, W.R.2
-
9
-
-
0024576318
-
Plasma endotoxin as a predictor of multiple organ failure and death in systemic meningococcal disease
-
Brandtzaeg P, Kierulf P, Gaustad P, Shulberg A, Bruun JM et al.: Plasma endotoxin as a predictor of multiple organ failure and death in systemic meningococcal disease. J Infect Dis 1989; 159: 195-204.
-
(1989)
J Infect Dis
, vol.159
, pp. 195-204
-
-
Brandtzaeg, P.1
Kierulf, P.2
Gaustad, P.3
Shulberg, A.4
Bruun, J.M.5
-
10
-
-
0023829270
-
Endotoxemia: An early predictor of septicaemia in febrile patients
-
van Deventer SJ, Buller HR, ten Cate JW, Sturk A, Pauw W: Endotoxemia: an early predictor of septicaemia in febrile patients. Lancet 1988/I: 605-609.
-
(1988)
Lancet
, vol.1
, pp. 605-609
-
-
Van Deventer, S.J.1
Buller, H.R.2
Ten Cate, J.W.3
Sturk, A.4
Pauw, W.5
-
11
-
-
0025367679
-
The staphylococcal enterotoxins and their relatives
-
Marrack P, Kappler J: The staphylococcal enterotoxins and their relatives. Science 1990; 248: 705-711.
-
(1990)
Science
, vol.248
, pp. 705-711
-
-
Marrack, P.1
Kappler, J.2
-
12
-
-
0028501020
-
CD14 is a pattern recognition receptor
-
Pugin J, Heumann D, Tomasz A, Kravchenko UU, Akamatsu Y et al.: CD14 is a pattern recognition receptor. Immunity 1994; 1: 509-516.
-
(1994)
Immunity
, vol.1
, pp. 509-516
-
-
Pugin, J.1
Heumann, D.2
Tomasz, A.3
Kravchenko, U.U.4
Akamatsu, Y.5
-
13
-
-
34447498003
-
CD14 dependant and independant activation of monocytes stimulated by gram-positive bacterial cell wall fragments
-
New Orleans
-
Majcherczyk PA, Knaup M, Pugin J, Glauser MP, Moreillon P, Heumann D: CD14 dependant and independant activation of monocytes stimulated by gram-positive bacterial cell wall fragments [Abstract]. 36th Interscience Conference on Anti-microbial Agents and Chemotherapy. New Orleans, 1996: G51.
-
(1996)
36th Interscience Conference on Anti-microbial Agents and Chemotherapy
-
-
Majcherczyk, P.A.1
Knaup, M.2
Pugin, J.3
Glauser, M.P.4
Moreillon, P.5
Heumann, D.6
-
14
-
-
0019916532
-
Role of peptidoglycan from Staphylococcus aureus in leukopenia, thrombocytopenia, and complement activation associated with bacteremia
-
Spika JS, Peterson PK, Wilkinson BJ, Hammerschmidt DE, Verbrugh HA et al.: Role of peptidoglycan from Staphylococcus aureus in leukopenia, thrombocytopenia, and complement activation associated with bacteremia. J Infect Dis 1982; 146: 227-234.
-
(1982)
J Infect Dis
, vol.146
, pp. 227-234
-
-
Spika, J.S.1
Peterson, P.K.2
Wilkinson, B.J.3
Hammerschmidt, D.E.4
Verbrugh, H.A.5
-
15
-
-
0019816671
-
The role of activated complement and granulocytes in shock states and myocardial infarction
-
Jacobs HS: The role of activated complement and granulocytes in shock states and myocardial infarction. J Lab Clin Med 1981; 98: 645-654.
-
(1981)
J Lab Clin Med
, vol.98
, pp. 645-654
-
-
Jacobs, H.S.1
-
17
-
-
0020551581
-
Activation of purified human plasma prekallikrein triggered by cell wall fractions of Escherichia coli and Staphylococcus aureus
-
Kalter ES, van Dijk WC, Timmerman A, Verhoef J, Bouma BN: Activation of purified human plasma prekallikrein triggered by cell wall fractions of Escherichia coli and Staphylococcus aureus. J Infect Dis 1983; 148: 682-691.
-
(1983)
J Infect Dis
, vol.148
, pp. 682-691
-
-
Kalter, E.S.1
Van Dijk, W.C.2
Timmerman, A.3
Verhoef, J.4
Bouma, B.N.5
-
18
-
-
0025213938
-
Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: Effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway inhibitor activity
-
Warr TA, Mohan Rao LV, Rapaport SI: Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway inhibitor activity. Blood 1990; 75: 1481-1489.
-
(1990)
Blood
, vol.75
, pp. 1481-1489
-
-
Warr, T.A.1
Mohan Rao, L.V.2
Rapaport, S.I.3
-
19
-
-
0024524898
-
The role of plasma proteases in septic shock
-
Colman RW: The role of plasma proteases in septic shock. N Engl J Med 1989; 320: 1207-1209.
-
(1989)
N Engl J Med
, vol.320
, pp. 1207-1209
-
-
Colman, R.W.1
-
20
-
-
0025107568
-
Structure and function of lipopolysaccharide binding protein
-
Schumann RR, Leong SR, Flaggs GW, Gray PW, Wright SD et al.: Structure and function of lipopolysaccharide binding protein. Science 1990; 249: 1429-1431.
-
(1990)
Science
, vol.249
, pp. 1429-1431
-
-
Schumann, R.R.1
Leong, S.R.2
Flaggs, G.W.3
Gray, P.W.4
Wright, S.D.5
-
21
-
-
0025166114
-
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
-
Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC: CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 1990; 249: 1431-1433.
-
(1990)
Science
, vol.249
, pp. 1431-1433
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
Ulevitch, R.J.4
Mathison, J.C.5
-
22
-
-
0026552706
-
Control of lipopolysaccharide (LPS) binding and LPS-induced tumor necrosis factor secretion in human peripheral blood monocytes
-
Heumann D, Gallay P, Barras C, Zaech P, Ulevitch RJ et al.: Control of lipopolysaccharide (LPS) binding and LPS-induced tumor necrosis factor secretion in human peripheral blood monocytes. J Immunol 1992; 148: 3505-3512.
-
(1992)
J Immunol
, vol.148
, pp. 3505-3512
-
-
Heumann, D.1
Gallay, P.2
Barras, C.3
Zaech, P.4
Ulevitch, R.J.5
-
23
-
-
0026463120
-
Soluble CD14 participates in the response of cells to lipopolysaccharide
-
Frey EA, Miller DS, Jahr TG, Sundan A, Bazil V et al.: Soluble CD14 participates in the response of cells to lipopolysaccharide. J Immunol 1992; 176: 1665-1671.
-
(1992)
J Immunol
, vol.176
, pp. 1665-1671
-
-
Frey, E.A.1
Miller, D.S.2
Jahr, T.G.3
Sundan, A.4
Bazil, V.5
-
24
-
-
0027446922
-
Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14
-
Pugin J, Schurer-Maly CC, Leturcq D, Mariarty A, Ulevitch RJ et al.: Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. Proc Natl Acad Sci USA 1993; 90: 2744-2748.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2744-2748
-
-
Pugin, J.1
Schurer-Maly, C.C.2
Leturcq, D.3
Mariarty, A.4
Ulevitch, R.J.5
-
25
-
-
0030041949
-
Function of soluble CD14 in serum from patients with septic shock
-
Landmann R, Reber AM, Sansano S, Zimmerli W: Function of soluble CD14 in serum from patients with septic shock. J Infect Dis 1996; 173: 661-668.
-
(1996)
J Infect Dis
, vol.173
, pp. 661-668
-
-
Landmann, R.1
Reber, A.M.2
Sansano, S.3
Zimmerli, W.4
-
26
-
-
0025152660
-
The role of cytokine mediators in septic shock
-
Tracey KJ, Lowry SF: The role of cytokine mediators in septic shock. Adv Surg 1990; 23: 21-26.
-
(1990)
Adv Surg
, vol.23
, pp. 21-26
-
-
Tracey, K.J.1
Lowry, S.F.2
-
27
-
-
0023491364
-
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteremia
-
Tracey KJ, Fong Y, Hesse DG, Manogue KR, Lee AT et al.: Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteremia. Nature 1987; 330: 662-664.
-
(1987)
Nature
, vol.330
, pp. 662-664
-
-
Tracey, K.J.1
Fong, Y.2
Hesse, D.G.3
Manogue, K.R.4
Lee, A.T.5
-
28
-
-
0023884204
-
Participation of tumor necrosis factor in the mediation of bacterial lipopolysaccharide-induced injury in rabbits
-
Mathison FC, Wolfson E, Ulevitch RJ: Participation of tumor necrosis factor in the mediation of bacterial lipopolysaccharide-induced injury in rabbits. J Clin Invest 1988; 81: 1925-1937.
-
(1988)
J Clin Invest
, vol.81
, pp. 1925-1937
-
-
Mathison, F.C.1
Wolfson, E.2
Ulevitch, R.J.3
-
29
-
-
0022411888
-
Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin
-
Beutler B, Milsark IW, Cerami A: Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 1985; 229: 869-871.
-
(1985)
Science
, vol.229
, pp. 869-871
-
-
Beutler, B.1
Milsark, I.W.2
Cerami, A.3
-
30
-
-
0025333163
-
Prophylactic and therapeutic effects of a monoclonal antibody to tumor necrosis factor-a in experimental gram-negative shock
-
Silva AT, Bayston KF, Cohen J: Prophylactic and therapeutic effects of a monoclonal antibody to tumor necrosis factor-a in experimental gram-negative shock. J Infect Dis 1990; 162: 421-427.
-
(1990)
J Infect Dis
, vol.162
, pp. 421-427
-
-
Silva, A.T.1
Bayston, K.F.2
Cohen, J.3
-
31
-
-
0026079224
-
Divergent efficacy of antibody to tumor necrosis factor-a in intravascular and peritonitis models of sepsis
-
Bagby GJ, Plessala KJ, Wilson LA, Thompson KJ, Nelson S: Divergent efficacy of antibody to tumor necrosis factor-a in intravascular and peritonitis models of sepsis. J Infect Dis 1990; 163: 83-88.
-
(1990)
J Infect Dis
, vol.163
, pp. 83-88
-
-
Bagby, G.J.1
Plessala, K.J.2
Wilson, L.A.3
Thompson, K.J.4
Nelson, S.5
-
32
-
-
0025258906
-
Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis
-
Echtenacher B, Falk W, Männel DN, Krammer PH: Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis. J Immunol 1990; 145: 3762-3766.
-
(1990)
J Immunol
, vol.145
, pp. 3762-3766
-
-
Echtenacher, B.1
Falk, W.2
Männel, D.N.3
Krammer, P.H.4
-
33
-
-
0026568118
-
Cytokine production after intravenous or peritoneal gram-negative bacterial challenge in mice. Comparative protective efficacy of antibodies to tumor necrosis factor-alpha and to lipopolysaccharide
-
Zanetti G, Heumann D, Gerain J, Kohler J, Abbet P et al.: Cytokine production after intravenous or peritoneal gram-negative bacterial challenge in mice. Comparative protective efficacy of antibodies to tumor necrosis factor-alpha and to lipopolysaccharide. J Immunol 1992; 148: 1890-1897.
-
(1992)
J Immunol
, vol.148
, pp. 1890-1897
-
-
Zanetti, G.1
Heumann, D.2
Gerain, J.3
Kohler, J.4
Abbet, P.5
-
34
-
-
0025777448
-
Interleukin-1 and interleukin-1 antagonism
-
Dinarello CA: Interleukin-1 and interleukin-1 antagonism. Blood 1991; 77: 1627-1652.
-
(1991)
Blood
, vol.77
, pp. 1627-1652
-
-
Dinarello, C.A.1
-
35
-
-
0023758635
-
Interleukin-1 potentiates the lethal effect of tumor necrosis factor-alpha/cachectin in mice
-
Waage A, Espevik T: Interleukin-1 potentiates the lethal effect of tumor necrosis factor-alpha/cachectin in mice. J Exp Med 1988; 167: 1987-1992.
-
(1988)
J Exp Med
, vol.167
, pp. 1987-1992
-
-
Waage, A.1
Espevik, T.2
-
36
-
-
0023749693
-
Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura
-
Girardin E, Grau GE, Dayer JM, Roux-Lombard P, Lambert PH: Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura. N Engl J Med 1988; 319: 397-400.
-
(1988)
N Engl J Med
, vol.319
, pp. 397-400
-
-
Girardin, E.1
Grau, G.E.2
Dayer, J.M.3
Roux-Lombard, P.4
Lambert, P.H.5
-
37
-
-
0023094408
-
Association between tumor necrosis factor in serum and fatal outcome in patients with meningococcal disease
-
Waage A, Halstensen A, Espevik T: Association between tumor necrosis factor in serum and fatal outcome in patients with meningococcal disease. Lancet 1987; 1: 355-357.
-
(1987)
Lancet
, vol.1
, pp. 355-357
-
-
Waage, A.1
Halstensen, A.2
Espevik, T.3
-
38
-
-
0025266645
-
Prognosis values of tumor necrosis factor/cachectin, interleukin-1, interferon-alpha and interferon-gamma in the serum of patients with septic shock
-
Calandra T, Baumgartner JD, Grau GE, Wu MM, Lambert PH et al.: Prognosis values of tumor necrosis factor/cachectin, interleukin-1, interferon-alpha and interferon-gamma in the serum of patients with septic shock. J Infect Dis 1990; 161: 982-987.
-
(1990)
J Infect Dis
, vol.161
, pp. 982-987
-
-
Calandra, T.1
Baumgartner, J.D.2
Grau, G.E.3
Wu, M.M.4
Lambert, P.H.5
-
39
-
-
0025757275
-
Inhibition of interleukin-1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 receptor antagonist and anti-IL-1 receptor monoclonal antibody
-
McIntyre KW, Stepan GJ, Kolinsky KD, Benjamin WR, Plocinski JM et al.: Inhibition of interleukin-1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 receptor antagonist and anti-IL-1 receptor monoclonal antibody. J Exp Med 1991; 173: 931-939.
-
(1991)
J Exp Med
, vol.173
, pp. 931-939
-
-
McIntyre, K.W.1
Stepan, G.J.2
Kolinsky, K.D.3
Benjamin, W.R.4
Plocinski, J.M.5
-
40
-
-
0025852720
-
A specific receptor antagonist to interleukin-1 prevents Escherichia coli-induced shock in rabbits
-
Wakabayashi G, Gelfand JA, Burke JF, Thompson RC, Dinarello CA: A specific receptor antagonist to interleukin-1 prevents Escherichia coli-induced shock in rabbits. FASEB J 1991; 5: 338-343.
-
(1991)
FASEB J
, vol.5
, pp. 338-343
-
-
Wakabayashi, G.1
Gelfand, J.A.2
Burke, J.F.3
Thompson, R.C.4
Dinarello, C.A.5
-
41
-
-
0025904893
-
A recombinant human receptor antagonist to interleukin-1 improves survival after lethal endotoxinemia in mice
-
Alexander HR, Doherty GM, Buresh CM, Venzon DJ, Norton JA: A recombinant human receptor antagonist to interleukin-1 improves survival after lethal endotoxinemia in mice. J Exp Med 1991; 173: 1029-1032.
-
(1991)
J Exp Med
, vol.173
, pp. 1029-1032
-
-
Alexander, H.R.1
Doherty, G.M.2
Buresh, C.M.3
Venzon, D.J.4
Norton, J.A.5
-
42
-
-
0025871289
-
High circulating levels of interleukin-6 in patients with septic shock: Evolution during sepsis, prognostic value, and interplay with other cytokines
-
Calandra T, Gerain J, Heumann D, Baumgartner JD, Glauser MP, The Swiss-Dutch J5 Immunoglobulin Study Group: High circulating levels of interleukin-6 in patients with septic shock: evolution during sepsis, prognostic value, and interplay with other cytokines. Am J Med 1991; 91: 23-29.
-
(1991)
Am J Med
, vol.91
, pp. 23-29
-
-
Calandra, T.1
Gerain, J.2
Heumann, D.3
Baumgartner, J.D.4
Glauser, M.P.5
-
43
-
-
0025943512
-
Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality
-
Lesslauer W, Tabuchi H, Gentz R, Brockhaus M, Schlaeger EJ et al.: Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality. Eur J Immunol 1991; 21: 2883-2886.
-
(1991)
Eur J Immunol
, vol.21
, pp. 2883-2886
-
-
Lesslauer, W.1
Tabuchi, H.2
Gentz, R.3
Brockhaus, M.4
Schlaeger, E.J.5
-
44
-
-
0026761609
-
Endotoxin, septic shock and acute lung injury: Neutrophils, macrophages, and inflammatory mediators
-
Welbourn CRB, Young Y: Endotoxin, septic shock and acute lung injury: neutrophils, macrophages, and inflammatory mediators. Br J Surg 1992; 79: 998-1003.
-
(1992)
Br J Surg
, vol.79
, pp. 998-1003
-
-
Welbourn, C.R.B.1
Young, Y.2
-
45
-
-
0026006260
-
The pro-inflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome
-
Dinarello CA: The pro-inflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome. J Infect Dis 1991; 163: 1177-1184.
-
(1991)
J Infect Dis
, vol.163
, pp. 1177-1184
-
-
Dinarello, C.A.1
-
46
-
-
0024518299
-
Effects of cytokines on vascular endothelium: Their role in vascular and immune injury
-
Cotran RS, Pober JS: Effects of cytokines on vascular endothelium: their role in vascular and immune injury. Kidney Int 1989; 35: 969-975.
-
(1989)
Kidney Int
, vol.35
, pp. 969-975
-
-
Cotran, R.S.1
Pober, J.S.2
-
47
-
-
34447496020
-
Platelet activating factor mediates hemodynamic changes and lung injury in endotoxin-treated rats
-
Chang SW, Fedderson CO, Henson PM, Voelkel NF: Platelet activating factor mediates hemodynamic changes and lung injury in endotoxin-treated rats. J Clin Invest 1990; 171: 439-448.
-
(1990)
J Clin Invest
, vol.171
, pp. 439-448
-
-
Chang, S.W.1
Fedderson, C.O.2
Henson, P.M.3
Voelkel, N.F.4
-
48
-
-
0025334367
-
Regulatory functions of the vascular endothelium
-
Vane JR, Angaard EE, Botting RM: Regulatory functions of the vascular endothelium. N Engl J Med 1990; 323: 27-36.
-
(1990)
N Engl J Med
, vol.323
, pp. 27-36
-
-
Vane, J.R.1
Angaard, E.E.2
Botting, R.M.3
-
49
-
-
0026571689
-
Inhibition of NO synthesis in septic shock
-
Hotchkiss RS, Parker JL, Adams HR: Inhibition of NO synthesis in septic shock. Lancet 1992; 339: 434-435.
-
(1992)
Lancet
, vol.339
, pp. 434-435
-
-
Hotchkiss, R.S.1
Parker, J.L.2
Adams, H.R.3
-
50
-
-
0027055199
-
Inhibition of nitric oxide synthesis improves survival in a murine peritonitis model of sepsis that is not cured by antibiotics alone
-
Teale DM, Atkinson AM: Inhibition of nitric oxide synthesis improves survival in a murine peritonitis model of sepsis that is not cured by antibiotics alone. J Antimicrob Chemother 1992; 30: 839-842.
-
(1992)
J Antimicrob Chemother
, vol.30
, pp. 839-842
-
-
Teale, D.M.1
Atkinson, A.M.2
-
51
-
-
0026674684
-
N omega amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality in awake canines challenged with endotoxin
-
Cobb JP, Natanson C, Hoffman WD, Lodato RF, Banks S et al.: N omega amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality in awake canines challenged with endotoxin. J Exp Med 1992; 176: 1175-1182.
-
(1992)
J Exp Med
, vol.176
, pp. 1175-1182
-
-
Cobb, J.P.1
Natanson, C.2
Hoffman, W.D.3
Lodato, R.F.4
Banks, S.5
-
52
-
-
0026346162
-
Effect of nitric oxide synthetase inhibitors on hypotension in patients with septic shock
-
Petros A, Bennett D, Vallance P: Effect of nitric oxide synthetase inhibitors on hypotension in patients with septic shock. Lancet 1991; 338: 1557-1558.
-
(1991)
Lancet
, vol.338
, pp. 1557-1558
-
-
Petros, A.1
Bennett, D.2
Vallance, P.3
-
53
-
-
0029035476
-
Altered immune response in mice lacking inducible nitric oxide synthase
-
Wei XQ, Charles IG, Smith A, Ure J, Feng GJ et al.: Altered immune response in mice lacking inducible nitric oxide synthase. Nature 1995; 375: 408-411.
-
(1995)
Nature
, vol.375
, pp. 408-411
-
-
Wei, X.Q.1
Charles, I.G.2
Smith, A.3
Ure, J.4
Feng, G.J.5
-
54
-
-
0019986518
-
Plasma thromboxane concentrations are raised in patients dying with septic shock
-
Reines HD, Halushka PV, Cook JA, Wise WC, Rambo W: Plasma thromboxane concentrations are raised in patients dying with septic shock. Lancet 1982; 2: 174-175.
-
(1982)
Lancet
, vol.2
, pp. 174-175
-
-
Reines, H.D.1
Halushka, P.V.2
Cook, J.A.3
Wise, W.C.4
Rambo, W.5
-
56
-
-
0020791999
-
Analysis of 1186 episodes of gram-negative bacteremia in non-university hospitals: The effects of antimicrobial therapy
-
Bryan CS, Reynold KL, Brenner ER: Analysis of 1186 episodes of gram-negative bacteremia in non-university hospitals: the effects of antimicrobial therapy. Rev Infect Dis 1983; 5: 629-638.
-
(1983)
Rev Infect Dis
, vol.5
, pp. 629-638
-
-
Bryan, C.S.1
Reynold, K.L.2
Brenner, E.R.3
-
58
-
-
0020515919
-
Prospective randomized trial of piperacilline monotherapy versus carboxypenicillin-aminoglycoside combination regimens in the empirical treatment of serious bacterial infections
-
Gribble MJ, Chow AW, Naiman SC, Smith JA, Bowie WR et al.: Prospective randomized trial of piperacilline monotherapy versus carboxypenicillin-aminoglycoside combination regimens in the empirical treatment of serious bacterial infections. Antimicrob Agents Chemother 1983; 24: 388-393.
-
(1983)
Antimicrob Agents Chemother
, vol.24
, pp. 388-393
-
-
Gribble, M.J.1
Chow, A.W.2
Naiman, S.C.3
Smith, J.A.4
Bowie, W.R.5
-
59
-
-
0028287227
-
Prospective randomized comparison of imipenem monotherapy with imipenem plus netilmicin for treatment of severe infections in non-neutropenic patients
-
Cometta A, Baumgartner JD, Lew D, Zimmerli W, Pittet D et al.: Prospective randomized comparison of imipenem monotherapy with imipenem plus netilmicin for treatment of severe infections in non-neutropenic patients. Antimicrob Agents Chemother 1994; 38: 1309-1313.
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 1309-1313
-
-
Cometta, A.1
Baumgartner, J.D.2
Lew, D.3
Zimmerli, W.4
Pittet, D.5
-
60
-
-
0030014727
-
Use of aminoglycosides: The Swiss consensus
-
Zimmerli W, Lew DP, The Swiss Society of Infectious Diseases: Use of aminoglycosides: the Swiss consensus. Schweiz Med Wochenschr 1996; 126 (Suppl. 76): 5S-8S.
-
(1996)
Schweiz Med Wochenschr
, vol.126
, Issue.76 SUPPL.
-
-
Zimmerli, W.1
Lew, D.P.2
-
61
-
-
0025350856
-
Association between protective efficacy of anti-lipopolysaccharide (LPS) antibodies and suppression of LPS-induced tumor necrosis factor-a and interleukin-6. Comparison of O side chain-specific antibodies with core LPS antibodies
-
Baumgartner JD, Heumann D, Gerain J, Weinbreck P, Grau GE et al.: Association between protective efficacy of anti-lipopolysaccharide (LPS) antibodies and suppression of LPS-induced tumor necrosis factor-a and interleukin-6. Comparison of O side chain-specific antibodies with core LPS antibodies. J Exp Med 1990; 171: 889-896.
-
(1990)
J Exp Med
, vol.171
, pp. 889-896
-
-
Baumgartner, J.D.1
Heumann, D.2
Gerain, J.3
Weinbreck, P.4
Grau, G.E.5
-
62
-
-
0019906260
-
Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli
-
Ziegler EJ, McCutchan JA, Fierer J, Glauser MP, Sadoff JC et al.: Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli. N Engl J Med 1982; 307: 1225-1230.
-
(1982)
N Engl J Med
, vol.307
, pp. 1225-1230
-
-
Ziegler, E.J.1
McCutchan, J.A.2
Fierer, J.3
Glauser, M.P.4
Sadoff, J.C.5
-
63
-
-
0021843019
-
Prevention of gram-negative shock and death in surgical patients by prophylactic antibody to endotoxin core glycolipid
-
Baumgartner JD, Glauser MP, McCutchan JA, Ziegler EJ, van Melle G et al.: Prevention of gram-negative shock and death in surgical patients by prophylactic antibody to endotoxin core glycolipid. Lancet 1985; 2: 59-63.
-
(1985)
Lancet
, vol.2
, pp. 59-63
-
-
Baumgartner, J.D.1
Glauser, M.P.2
McCutchan, J.A.3
Ziegler, E.J.4
Van Melle, G.5
-
64
-
-
0026780301
-
Treatment of severe infectious purpura in children with human plasma from donors immunized with Escherichia coli J5: A prospective double-blind study
-
J5 Study Group: Treatment of severe infectious purpura in children with human plasma from donors immunized with Escherichia coli J5: a prospective double-blind study. J Infect Dis 1992; 165: 695-701.
-
(1992)
J Infect Dis
, vol.165
, pp. 695-701
-
-
-
65
-
-
0025917510
-
A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis
-
Greenman RL, Schein RM, Martin MA, Wenzel RP, McIntyre HR et al.: A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group. JAMA 1991; 266: 1097-1102.
-
(1991)
JAMA
, vol.266
, pp. 1097-1102
-
-
Greenman, R.L.1
Schein, R.M.2
Martin, M.A.3
Wenzel, R.P.4
McIntyre, H.R.5
-
66
-
-
0026016470
-
Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial
-
Ziegler EJ, Fisher CJ, Sprung CL, Straube RC, Sadoff JC et al.: Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. N Engl J Med 1991; 324: 429-436.
-
(1991)
N Engl J Med
, vol.324
, pp. 429-436
-
-
Ziegler, E.J.1
Fisher, C.J.2
Sprung, C.L.3
Straube, R.C.4
Sadoff, J.C.5
-
67
-
-
0028557981
-
Treatment of septic shock with human monoclonal antibody HA-IA. A randomized, double-blind, placebo-controlled trial
-
CHESS Trial Study Group
-
Mc Closkey RV, Strauber RC, Sanders C, Smith SM, Smith CR: Treatment of septic shock with human monoclonal antibody HA-IA. A randomized, double-blind, placebo-controlled trial. CHESS Trial Study Group. Ann Intern Med 1994; 121: 1-5.
-
(1994)
Ann Intern Med
, vol.121
, pp. 1-5
-
-
Mc Closkey, R.V.1
Strauber, R.C.2
Sanders, C.3
Smith, S.M.4
Smith, C.R.5
-
68
-
-
0029043636
-
A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: Results of a prospective, multicenter, randomized, controlled trial
-
Bone RC, Balk RA, Fein AM, Perl TM, Wenzel RP et al.: A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: results of a prospective, multicenter, randomized, controlled trial. Crit Care Med 1995; 23: 994-1006.
-
(1995)
Crit Care Med
, vol.23
, pp. 994-1006
-
-
Bone, R.C.1
Balk, R.A.2
Fein, A.M.3
Perl, T.M.4
Wenzel, R.P.5
-
69
-
-
0026265606
-
Lipid A analogs aimed at preventing the detrimental effects of endotoxin
-
Young LS, Glauser MP (eds): Philadelphia: WB Saunders
-
Stütz P, Liehl E: Lipid A analogs aimed at preventing the detrimental effects of endotoxin. In: Young LS, Glauser MP (eds): Gram-negative septicemia and septic shock. Philadelphia: WB Saunders, 1991: 847-874.
-
(1991)
Gram-negative Septicemia and Septic Shock
, pp. 847-874
-
-
Stütz, P.1
Liehl, E.2
-
70
-
-
9344246862
-
Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock: A multicenter, randomized, placebo-controlled, dose-ranging study
-
Reinhart K, Wiegand-Löhnert C, Grimminger F, Kaul M, Withington S et al.: Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock: a multicenter, randomized, placebo-controlled, dose-ranging study. Crit Care Med 1996; 24: 733-742.
-
(1996)
Crit Care Med
, vol.24
, pp. 733-742
-
-
Reinhart, K.1
Wiegand-Löhnert, C.2
Grimminger, F.3
Kaul, M.4
Withington, S.5
-
71
-
-
0028957549
-
Efficacy and safety of monoclonal antibody to human tumor necrosis factor-a in patients with sepsis syndrome
-
Abraham E, Wunderink R, Silverman H, Perl TM, Nasraway S et al.: Efficacy and safety of monoclonal antibody to human tumor necrosis factor-a in patients with sepsis syndrome. JAMA 1995; 273: 934-941.
-
(1995)
JAMA
, vol.273
, pp. 934-941
-
-
Abraham, E.1
Wunderink, R.2
Silverman, H.3
Perl, T.M.4
Nasraway, S.5
-
72
-
-
0029835023
-
Intersept: An international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-a in patients with sepsis
-
Cohen J, Carlet J, The Intersept Study Group: Intersept: an international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-a in patients with sepsis. Crit Care Med 1996; 24: 1431-1440.
-
(1996)
Crit Care Med
, vol.24
, pp. 1431-1440
-
-
Cohen, J.1
Carlet, J.2
-
73
-
-
0025721017
-
Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin
-
Ashkenazi A, Masters SA, Capon DJ: Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin. Proc Natl Acad Sci USA 1991; 88: 10535-10539.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 10535-10539
-
-
Ashkenazi, A.1
Masters, S.A.2
Capon, D.J.3
-
74
-
-
0025827590
-
A tumor necrosis factor receptor-IgG heavy chain chimeric protein as a bivalent-antagonist of TNF activity
-
Peppel K, Crawford D, Beutler B: A tumor necrosis factor receptor-IgG heavy chain chimeric protein as a bivalent-antagonist of TNF activity. J Exp Med 1991; 174: 1484-1488.
-
(1991)
J Exp Med
, vol.174
, pp. 1484-1488
-
-
Peppel, K.1
Crawford, D.2
Beutler, B.3
-
75
-
-
0029900294
-
Treatment of septic shock with the tumor necrosis factor receptor: Fc fusion protein
-
Fisher CJ, Agosti JM, Opal SM, Lowry SF, Balk RA et al.: Treatment of septic shock with the tumor necrosis factor receptor: Fc fusion protein. N Engl J Med 1996; 334: 1697-1702.
-
(1996)
N Engl J Med
, vol.334
, pp. 1697-1702
-
-
Fisher, C.J.1
Agosti, J.M.2
Opal, S.M.3
Lowry, S.F.4
Balk, R.A.5
-
76
-
-
34447496031
-
Ro 45-2081 (TNFR55-IgG1) in the treatment of patients with severe sepsis/septic shock: Preliminary results
-
Dauville, France
-
Abraham E, Glauser MP, Gelmont D, Kudsk K, Lew D et al: Ro 45-2081 (TNFR55-IgG1) in the treatment of patients with severe sepsis/septic shock: preliminary results. 3rd Annual Autumnal Sepsis Meeting, Dauville, France, 1995.
-
(1995)
3rd Annual Autumnal Sepsis Meeting
-
-
Abraham, E.1
Glauser, M.P.2
Gelmont, D.3
Kudsk, K.4
Lew, D.5
-
77
-
-
0028018567
-
Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: A randomized, open-label, placebo-controlled multicenter trial
-
Fisher CJ, Slotman GJ, Opal SM, Pribble JP, Bove RC et al.: Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial. Crit Care Med 1994; 22: 12-21.
-
(1994)
Crit Care Med
, vol.22
, pp. 12-21
-
-
Fisher, C.J.1
Slotman, G.J.2
Opal, S.M.3
Pribble, J.P.4
Bove, R.C.5
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