The effect of serum albumin on the radiolysis of DNA studied by constant field electrophoresis and compared to alterations caused by low molecular weight OH. scavengers

International Journal of Radiation Biology

Volumn 71, Issue 4, 1997, Pages 401-412

  Distel, L V R ^a   Schuessler, H ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; DIMETHYL SULFOXIDE; DNA; HYDROXYL RADICAL; SERUM ALBUMIN; TERT BUTYL ALCOHOL;

ARTICLE; CONTROLLED STUDY; ELECTROPHORESIS; PRIORITY JOURNAL; RADIOLYSIS; SCAVENGING SYSTEM;

LETHRINIDAE;

EID: 0030894932     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530097144012     Document Type: Article

References (33)

1. -) in aqueous solution. Journal of Physical and Chemical Reference Data, 17, 513-886.
2. CARTER, D. C. and HO, J. X., 1994, Structure of serum albumin. Advances in Protein Chemistry, 45, 153-203.
3. DAHM-DAPHI J. and DIKOMEY E., 1996, Rejoining of DNA double-strand breaks in X-irradiated CHO cells studied by constant- and graded-field gel electrophoresis. International Journal of Radiation Biology, 69, 615-621.
4. DISTEL, L. V.R., 1991, Messung von strahleninduzierten Protein-DNA-Quervernetzungen mit Nitrocellulosefilter. Thesis, University of Erlangen-Nürnberg (Germany) pp. 103.
5. HAGEN, U., 1967, Bestimmung von Einzel- und Doppelstrangbrüchen in bestrahlter Desoxyribonucleinsäure durch die Molekulargewichtsverteilung. Biochimica et biophysica acta, 134, 45-58.
6. HELD, K. D., 1986, Role of free radicals in radiation protection of DNA. In Free Radicals, Aging and Degenerative Diseases edited by Johnson, E. J. and Walford, R. (New York: Alan R. Liss), pp. 527-568.
7. HOWARD-FLANDERS, P., 1960, Effect of oxygen on the radiosensitivity of bacteriophage in the presence of sulfhydryl compounds. Nature, 186, 485-487.
8. HUTCHINSON, F., 1961, Sufhydryl groups and the oxygen effect on irradiated dilute solutions of enzymes and nucleic acids. Radiation Research, 14, 721-731.
9. JONES, G. D. D. and NEILL, P. O., 1991, Kinetics of radiation induced strand break formation in single stranded pyrimidine polynucleotides in the presence and absence of oxygen: a time resolved light scattering study. International Journal of Radiation Biology, 59, 1127-1145.
10. LAFLEUR, M. V. M., VAN HENVEL, M., WOLDHUIS, J. and LOMAN, H., 1978, Alkali-labile sites and post-irradiation effects in single stranded DNA induced by H radicals. International Journal of Radiation Biology, 33, 273-281.
11. LAFLEUR, M. V. M. and LOMAN, H., 1986, Radiation damage to ΦX174 DNA and biological effects. Radiation and Environmental Biophysics, 25, 159-173.
12. LINDENAU, D., HAGEN, U., and SCHNABEL, W., 1976. On the dynamics of DNA in aqueous solution. Pulse radiolysis studies using light scattering detection method. Radiation and Environmental Biophysics, 13, 287-294.
13. LIPHARD, M., BOTHE, E. and SCHULTE-FROHLINDE, 1990, The influence of glutathione on single-strand breakage in single-stranded DNA irradiated in aqueous solution in the absence and presence of oxygen. International Journal of Radiation Biology, 58, 589-602.
14. LLOYD, R. S., HAIDLE, C. W. and ROBERSON, D. L., 1978, Bleomycin specific fragmentation of double-stranded DNA. Biochemistry, 17, 1890-1896.
15. MCMENAMY, R. H., 1977, Albumin Binding Sites in Albumin Structure, Function and Uses. Edited by V. M. Rosenoer, M. Oratz and M. A. Rothschild (Oxford: Pergamon Press).
16. MILLIGAN, J. R., AGUILERA, J. A. and WARD, J. F., 1993, Variation of single-strand break yield with scavenger concentration for plasmid DNA irradiated in aqueous solution. Radiation Research, 133, 151-157.
17. MILLIGAN, J. R. and WARD, J. F., 1994, Yield of single-strand breaks due to attack on DNA by scavenger-derived radicals. Radiation Research, 137, 295-299.
18. NABBEN, F. J., VAN DER STROM, H. A. and LOMAN, H., 1983, Inactivation of biological active DNA by isopropanol and formate radicals. International Journal of Radiation Biology, 43, 495-504.
19. VAN RIJN, K., MAYER, T., BLOK, J., VERBERNE, J. B. and LOMAN, H., 1985, Reaction rate of OH radicals with ΦX174 DNA: influence of salt and scavengers. International Journal of Radiation Biology, 47, 309-317.
20. SCHNEIDER, M., TAUCHER-SCHOLZ, G., HEILMANN, J. and KRAFT, G., 1994, Combination of static-field gel electrophoresis and densitometric scanning for the determination of radiation-induced DNA double-strand breaks in CHO cells. Radiation and Environmental Biophysics, 33, 125-139.
21. SCHUESSLER, H. and DAVIES, J. V., 1983, Radiation-induced reduction reactions with bovine serum albumin. International Journal of Radiation Biology, 43, 291-301.
22. SCHUESSLER, H., GEIGER, A., HARTMANN, H. and STEINHEBER, J., 1987, The effect of protein on the radiolysis of DNA studied by gel filtration. International Journal of Radiation Biology, 51, 455-466.
23. SCHUESSLER, H. and HARTMANN, H., 1987, The effect of a protein on the radiolysis of DNA studied by HPLC and pulse radiolysis. International Journal of Radiation Biology, 52, 269-279.
24. SCHUESSLER, H. and JUNG, E., 1989, Protein-DNA crosslinks induced by primary and secondary radicals. International Journal of Radiation Biology, 56, 423-435.
25. SCHUESSLER, H., and SIEBER, R., 1993, Radiolysis of DNA studied by HPL-gelchromatography. International Journal of Radiation Biology, 63, 437-444.
26. SIDDIQI, M. A. AND BOTHE, E., 1987, Single- and double-strand break formation in DNA irradiated in aqueous solution: dependence on dose and OH radical scavenger concentration. Radiation Research, 112, 449-463.
27. SONNTAG, C. VON, 1987, The Chemical Basis of Radiation Biology (London: Taylor & Francis).
28. SONNTAG C, VON, HAGEN U., SCHÖN-BOPP A. and SCHULTE FROHLINDE D., 1981, Radiation-induced strand breaks in DNA: Chemical and enzymatic analysis of end groups and mechanistic aspects. Advances in Radiation Biology, 9, 109-142.
29. SPOTHEIM-MAURIZOT, M., FRANCHET, J., SABATTIER, R. and CHARLIER, M., 1991, DNA radiolysis by fast neutrons II. Oxygen, thiols and ionic strength effects. International Journal of Radiation Biology, 59, 1313-1324.
30. UDOVICIC L., MARK F., BOTHE E. and SCHULTE-FROHLINDE D., 1991, Non-homogeneous kinetics in the competition of single stranded calf-thymus DNA and low-molecular weight scavengers for OH radicals: a comparison of experimental data and theoretical models. International Journal of Radiation Biology, 59, 677-697.
31. WLODEK, D., BANATH, J. and OLIVE, P. L., 1991, Comparison between pulsed-field and constant-field gel electrophoresis for measurement of DNA double-strand breaks in irradiated Chinese hamster ovary cells. International Journal of Radiation Biology, 60, 779-790.
32. YAMAMOTO, O., OGAWA, M. and HOSKI, M., 1982, Comparison of the electrophoretic method with the sedimentation method for the analysis of DNA strand breaks. Radiation Research, 23, 385-398.
33. 2O-saturated solutions. Journal of Physical Chemistry, 86, 2078-2084.