메뉴 건너뛰기




Volumn 41, Issue 5, 1997, Pages 1017-1023

Removal of human immunodeficiency virus type 1 (HIV-1) protease inhibitors from preparations of immature HIV-1 virions does not result in an increase in infectivity or the appearance of mature morphology

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; KYNOSTATIN 272; POL PROTEIN; PROTEINASE INHIBITOR; SAQUINAVIR; VIRUS RNA;

EID: 0030894811     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.5.1017     Document Type: Article
Times cited : (15)

References (28)
  • 1
    • 0028122451 scopus 로고
    • Constitutive production of nonenveloped human immunodeficiency virus type 1 particles by a mammalian cell line and effects of a protease inhibitor on particle maturation
    • Babe, L. M., and C. S. Craik. 1994. Constitutive production of nonenveloped human immunodeficiency virus type 1 particles by a mammalian cell line and effects of a protease inhibitor on particle maturation. Antimicrob. Agents Chemother. 38:2430-2439.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 2430-2439
    • Babe, L.M.1    Craik, C.S.2
  • 2
    • 0028122752 scopus 로고
    • HIV protease inhibitors: Effects on viral maturation and physiologic function in macrophages
    • Bugelski, P. J., R. Kirsh, and T. K. Hart. 1994. HIV protease inhibitors: effects on viral maturation and physiologic function in macrophages. J. Leukocyte Biol. 56:374-380.
    • (1994) J. Leukocyte Biol. , vol.56 , pp. 374-380
    • Bugelski, P.J.1    Kirsh, R.2    Hart, T.K.3
  • 6
  • 8
    • 0342394457 scopus 로고
    • Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1
    • Gottlinger, H. G., J. G. Sodroski, and W. A. Haseltine. 1989. Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 86:3781-5785.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 3781-5785
    • Gottlinger, H.G.1    Sodroski, J.G.2    Haseltine, W.A.3
  • 9
    • 0342732474 scopus 로고    scopus 로고
    • A phase I trial of HIV protease inhibitor KNI-272 in patients with AIDS or symptomatic HIV infection
    • abstr. Mo.B. 1132. Vancouver, British Columbia, Canada. Transcontinental Printing. Inc., Vancouver, Canada
    • Humphrey, R., B.-Y. Nguyen, K. Wyvill, L. Shay, J. Lietzau, T. Ueno, H. Mitsuya, and R. Yarchoan. 1996. A phase I trial of HIV protease inhibitor KNI-272 in patients with AIDS or symptomatic HIV infection, abstr. Mo.B. 1132. In Abstracts of the International AIDS Meeting, Vancouver, British Columbia, Canada. Transcontinental Printing. Inc., Vancouver, Canada.
    • (1996) Abstracts of the International AIDS Meeting
    • Humphrey, R.1    Nguyen, B.-Y.2    Wyvill, K.3    Shay, L.4    Lietzau, J.5    Ueno, T.6    Mitsuya, H.7    Yarchoan, R.8
  • 10
    • 0002051756 scopus 로고
    • Quantitative assays for virus infectivity
    • A. Aldovini and B. D. Walker (ed.), Stockton Press, New York, N.Y.
    • Johnson, V. A., and R. E. Byington. 1990. Quantitative assays for virus infectivity, p. 71-76. In A. Aldovini and B. D. Walker (ed.), Techniques in HIV research. Stockton Press, New York, N.Y.
    • (1990) Techniques in HIV Research , pp. 71-76
    • Johnson, V.A.1    Byington, R.E.2
  • 13
    • 0027932364 scopus 로고
    • The activity of the protease of human immunodeficiency virus type 1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency
    • Kaplan, A., M. Manchester, and R. Swanstrom. 1994. The activity of the protease of human immunodeficiency virus type 1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency. J. Virol. 68:6782-6786.
    • (1994) J. Virol. , vol.68 , pp. 6782-6786
    • Kaplan, A.1    Manchester, M.2    Swanstrom, R.3
  • 14
    • 0025828543 scopus 로고
    • Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments
    • Kaplan, A. H., and R. Swanstrom. 1991. Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments. Proc. Natl. Acad. Sci. USA 88:4528-4532.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4528-4532
    • Kaplan, A.H.1    Swanstrom, R.2
  • 16
    • 0027205329 scopus 로고
    • Analysis of protein expression and virus-like particle formation in mammalian cell lines stably expressing HIV-1 gag and env gene products with or without active HIV proteinase
    • Krausslich, H.-G., C. Ochsenbauer, A.-M. Traenckner, K. Mergener, M. Facke, H. Gelderblom, and V. Bosch. 1993. Analysis of protein expression and virus-like particle formation in mammalian cell lines stably expressing HIV-1 gag and env gene products with or without active HIV proteinase. Virology 192:605-617.
    • (1993) Virology , vol.192 , pp. 605-617
    • Krausslich, H.-G.1    Ochsenbauer, C.2    Traenckner, A.-M.3    Mergener, K.4    Facke, M.5    Gelderblom, H.6    Bosch, V.7
  • 20
    • 0025857537 scopus 로고
    • Ro 31-8959/003
    • Martin, J. 1991. Ro 31-8959/003. Drugs future. 16:210-212.
    • (1991) Drugs Future , vol.16 , pp. 210-212
    • Martin, J.1
  • 21
    • 0026585458 scopus 로고
    • Analysis of HIV particle formation using transient expression of subviral constructs in mammalian cells
    • Mergener, K., M. Facke, R. Welker, V. Brinkmann, H. R. Gelderblom, and H. G. Krausslich. 1992. Analysis of HIV particle formation using transient expression of subviral constructs in mammalian cells. Virology 186:25-39.
    • (1992) Virology , vol.186 , pp. 25-39
    • Mergener, K.1    Facke, M.2    Welker, R.3    Brinkmann, V.4    Gelderblom, H.R.5    Krausslich, H.G.6
  • 22
    • 0026793703 scopus 로고
    • Kynostantin (KNI)-227 and -272, highly potent anti-HIV agents: Conformationally constrained tripeptide inhibitors of HIV protease containing allophenylnorstatine
    • Mimoto, T., J. Imai, S. Kisanuki, H. Enomoto, N. Hattori, K. Akaji, and Y. Kiso. 1992. Kynostantin (KNI)-227 and -272, highly potent anti-HIV agents: conformationally constrained tripeptide inhibitors of HIV protease containing allophenylnorstatine. Chem. Pharm. Bull. 40:2251-2253.
    • (1992) Chem. Pharm. Bull. , vol.40 , pp. 2251-2253
    • Mimoto, T.1    Imai, J.2    Kisanuki, S.3    Enomoto, H.4    Hattori, N.5    Akaji, K.6    Kiso, Y.7
  • 23
    • 0025005828 scopus 로고
    • Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity
    • Page, K. A., N. R. Landau, and D. R. Littman. 1990. Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity. J. Virol. 64:5270-5276.
    • (1990) J. Virol. , vol.64 , pp. 5270-5276
    • Page, K.A.1    Landau, N.R.2    Littman, D.R.3
  • 24
    • 0028232645 scopus 로고
    • DMP 323, a nonpeptide cyclic urea inhibitor of human immunodeficiency virus (HIV) protease, specifically and persistently blocks intracellular processing of HIV gag polyprotein
    • Rayner, M. M., B. C. Cordova, R. P. Meade, P. E. Aldrich, P. K. Jadhav, Y. Ru, and P. Y. S. Lam. 1994. DMP 323, a nonpeptide cyclic urea inhibitor of human immunodeficiency virus (HIV) protease, specifically and persistently blocks intracellular processing of HIV gag polyprotein. Antimicrob. Agents Chemother. 38:1635-1640.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 1635-1640
    • Rayner, M.M.1    Cordova, B.C.2    Meade, R.P.3    Aldrich, P.E.4    Jadhav, P.K.5    Ru, Y.6    Lam, P.Y.S.7
  • 26
    • 0026086220 scopus 로고
    • Mutagenesis of protease cleavage sites in the human immunodeficiency virus type 1 gag polyprotein
    • Tritch, R. J., Y. E. Cheng, F. H. Yin, and S. Erickson-Viitanen. 1991. Mutagenesis of protease cleavage sites in the human immunodeficiency virus type 1 gag polyprotein. J. Virol. 65:922-930.
    • (1991) J. Virol. , vol.65 , pp. 922-930
    • Tritch, R.J.1    Cheng, Y.E.2    Yin, F.H.3    Erickson-Viitanen, S.4
  • 28
    • 0018097388 scopus 로고
    • Relationship of retrovirus polyprotein cleavages to virion maturation studied with temperature-sensitive murine leukemia virus mutants
    • Witte, O. N., and D. Baltimore. 1978. Relationship of retrovirus polyprotein cleavages to virion maturation studied with temperature-sensitive murine leukemia virus mutants. J. Virol. 26:750-761.
    • (1978) J. Virol. , vol.26 , pp. 750-761
    • Witte, O.N.1    Baltimore, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.