BAY-12-8039

Drugs of the Future

Volumn 22, Issue 2, 1997, Pages 109-113

  Martel, A M ^a   Leeson, P A ^a   Castaner J ^a  

^a PROUS SCIENCE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1 CYCLOPROPYL 7 (2,8 DIAZABICYCLO[4,3,0]NON 8 YL) 6 FLUORO 8 METHOXY 1,4 DIHYDRO 4 OXO 3 QUINOLINE; 1 CYCLOPROPYL 7 (2,8 DIAZABICYCLO[4.3.0]NON 8 YL) 1,4 DIHYDRO 6 FLUORO 8 METHOXY 4 OXO 3 QUINOLINECARBOXYLIC ACID; AMPICILLIN; CEFPODOXIME; CIPROFLOXACIN; CLARITHROMYCIN; MOXIFLOXACIN; OFLOXACIN; PENICILLIN G; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; CONTROLLED STUDY; DRUG SAFETY; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; HUMAN; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHOTOTOXICITY; RESPIRATORY TRACT INFECTION; SHORT SURVEY; STREPTOCOCCUS PNEUMONIAE;

EID: 0030894801     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.1997.022.02.394449     Document Type: Short Survey

References (30)

1. Petersen, U., Bremm, K.-D., Dalhoff, A., Endermann, R., Heilmann, W., Krebs, A., Schenke, T. Synthesis and in vitro activity of BAY 12-8039, a new 8-methoxy-quinolone. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F1.
2. Petersen, U., Krebs, A., Schenke, T. et al. (Bayer AG). Quinolone- and napthyridone-carboxylic acid derivs. as antibacterial agents. DE 4208789, DE 4208792, EP 550903, JP 93217229.
3. Dalhoff, A., Fischer, E., Heidtmann, M., Hesse, D. In vitro activity of BAY 12-8039, a new 8-methoxy-quinolone. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F2.
4. Bauernfeind, A., Jungwirth, R. In vitro activity of the novel quinolone Bay 12-8039 in comparison with ciprofloxacin. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F3.
5. Herrington, J.A., Federici, J.A., Painter, B.G., Remy, J.M., Barbiero, M.L., Thurberg, B.E. In vitro activity of Bay 12-8039, a new quinolone. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F4.
6. Georgopoulos, A., Buxbaum, A., Graninger, W. Activity of BAY 12-8039 against 1154 clinical isolates of Streptococcus pneumoniae. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F5.
7. Visalli, M.A., Jacobs, M.R., Appelbaum, P.C. Antipneumococcal activity of Bay 12-8039, a new quinolone, compared to 3 other quinolones and 5 β-lactams. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F6.
8. Ruckdeschel, G., Lob, S. In vitro activity of a new 8-methoxyquinolone, BAY 12-8039, against Legionella spp. in comparison to ciprofloxacin (CIP), erythromycin (ERY) and rifampicin (RIF). 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F7.
9. Felmingham, D., Robbins, M.J., Leakey, A., Salman, H., Dencer, C., Clark, S., Ridgway, G.L., Grüneberg, R.N. In vitro activity of BAY 12-8039 against bacterial respiratory tract pathogens, mycoplasmas and obligate anaerobic bacteria. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F8.
10. Renaudin, H., Bebear, C.M., Boudjadja, A., Bebear, C. In vitro activity of Bay 12-8039, a new fluoroquinolone, against mycoplasmas. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F9.
11. Wise, R., Andrews, J.M., Brenwald, N. In vitro activity of a new fluoroquinolone Bay 12-8039 in comparison with other fluoroquinolones and β-lactams against recent isolates and Chlamydia. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F10.
12. Roblin, P.M., Hammerschlag, M.R. Activity of a new quinolone, Bay 12-8039 against Chlamydia pneumoniae in vitro. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F11.
13. Kitzis, M.D., Goldstein, F.W., Miegi, M., Acar, J.F. In vitro activity of Bay 12-8039 against multiply-resistant Staphylococcus aureus, Streptococcus pneumoniae and Enterococcus faecalis. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F12.
14. Federici, J.A., Herrington, J.A., Painter, B.G., Remy, J.M., Thurberg, B.E. The bactericidal activity of Bay 12-8039 against respiratory tract pathogens. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F13.
15. Nichterlein, T., Kretschmar, M., Hof, H. BAY 12-8039, a new quinolone derivative is superior to standard therapeutics in murine salmonellosis and listeriosis. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F14.
16. Aldridge, K.E., Ashcraft, D. Bay 12-8039, a new 8-methoxy-quinolone: In vitro activity against clinically important anaerobes. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F15.
17. Thomson, K.S., Backes, S.S., Sanders, C.C. Susceptibility to BAY 12-8039 of pneumococci and staphylococci with varying levels of ciprofloxacin resistance. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F16.
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19. Woodcock, J.M., Andrews, J.M., Boswell, F.J., Brenwald, N.P., Wise, R. In vitro activity of BAY 12-8039, a new fluoroquinolone. Antimicrob Agents Chemother 1997, 41: 101-6.
20. Waterbury, K., Wang, J.J., Barbiero, M., Federici, J., Ohlin, A.C., Huguenel, E.D. Efficacy of Bay 12-8039, a potent new quinolone, in mouse models of typical and atypical respiratory infection. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F18.
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23. Vesga, O., Conklin, R., Stamstad, T., Craig, W.A. Pharmacodynamic activity of Bay 12-8039 in animal infection models. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F22.
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26. Kern, A., Kanhai, W., Fröhde, R., Karl, W., Bader, A. BAY 12-8039,a new 8-methoxy-quinolone: Metabolism in rat, monkey, and man. 36th Intersci Conf Antimicrob Agents Chemother (Sept 15-18, New Orleans) 1996, Abst F23.
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