Insulin-induced hypoglycemia decreases uptake of 2-[F-18]fluoro-2- deoxy-D-glucose into experimental mammary carcinoma

Radiology

Volumn 203, Issue 1, 1997, Pages 169-172

  Torizuka, Tatsuo ^a   Fisher, Susan J ^a   Wahl, Richard L ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Breast neoplasms, experimental; Breast neoplasms, PET; Breast neoplasms, radionuclide studies; Fluorine; Glucose; Metabolism

Indexed keywords

FLUORODEOXYGLUCOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CARCINOMA; CANCER STAGING; CONTROLLED STUDY; DRUG INDUCED CANCER; DRUG UPTAKE; EXPERIMENTAL NEOPLASM; GLUCOSE BLOOD LEVEL; GLYCOLYSIS; HYPOGLYCEMIA; LIPID TRANSPORT; NONHUMAN; PRIORITY JOURNAL; RAT; VEIN PUNCTURE;

EID: 0030894715     PISSN: 00338419     EISSN: None     Source Type: Journal    
DOI: 10.1148/radiology.203.1.9122387     Document Type: Article

References (32)

1. Adler LP, Blair HF, Makley JT, et al. Noninvasive grading of musculoskeletal tumors using PET. J Nucl Med 1991; 32:1508-1512.
2. Wahl RL, Cody RL, Hutchins GD, Mudgett EE. Primary and metastatic breast carcinoma: initial clinical evaluation with PET with the radiolabeled glucose analogue 2-[F-18]-fluoro-2-deoxy-D-glucose. Radiology 1991; 179:765-770.
3. Hawkins RA, Hoh C, Glaspy J, et al. The role of positron emission tomography in oncology and other whole-body applications. Semin Nucl Med 1992; 22:268-284.
4. Wahl RL, Quint LE, Greenough RL, Meyer CR, White RI, Orringer MB. Staging of mediastinal non-small cell lung cancer with FDG PET, CT, and fusion images: preliminary prospective evaluation. Radiology 1994; 191:371-377.
5. Inokuma T, Tamaki N, Torizuka T, et al. Evaluation of pancreatic tumors with positron emission tomography and F-18 fluorodeoxyglucose: comparison with CT and US. Radiology 1995; 195:345-352.
6. Minn H, Zasadny KR, Quint LE, Wahl RL. Lung cancer: reproducibility of quantitative measurements for evaluating 2-[F-18]-fluoro-2-deoxy-D-glucose uptake at PET. Radiology 1995; 196:167-173.
7. Haberkorn U, Strauss LG, Dimitrakopoulou A, et al. PET studies of fluorodeoxyglucose metabolism in patients with recurrent colorectal tumors receiving radiotherapy. J Nucl Med 1991; 32:1485-1490.
8. Torizuka T, Tamaki N, Inokuma T, et al. Value of fluorine-18-FDG-PET to monitor hepatocellular carcinoma after interventional therapy. J Nucl Med 1994; 35:1965-1969.
9. Wahl RL, Zasadny K, Helvie M, Hutchins GD, Weber B, Cody R. Metabolic monitoring of breast cancer chemohormonotherapy using positron emission tomography: initial evaluation. J Clin Oncol 1993; 11:2101-2111.
10. Wahl RL, Henry CA, Ethier SP. Serum glucose: effects on tumor and normal tissue accumulation of 2-[F-18]-fluoro-2-deoxy-D-glucose in rodents with mammary carcinoma. Radiology 1992; 183:643-647.
11. Langen KJ, Braun U, Kops ER, et al. The influence of plasma glucose levels on fluorine-18-fluorodeoxyglucose uptake in bronchial carcinomas. J Nucl Med 1993; 34:355-359.
12. Lindholm P, Minn H, Leskinen-Kallio S, Bergman J, Ruotsalainen U, Joensuu H. Influence of the blood glucose concentration on FDG uptake in cancer: a PET study. J Nucl Med 1993; 34:1-6.
13. Ethier SP, Cundiff KC. Importance of extended growth potential and growth factor independence on in vivo neoplastic potential of primary rat mammary carcinoma cells. Cancer Res 1987; 47:5316-5322.
14. Stein MW. D-glucose: determination with hexokinase and glucose-6-phosphate dehydrogenase. In: Berrmever HU, ed. Methods of enzymatic analysis. New York, NY: Academic Press, 1963; 12.
15. Kubota K, Matsuzawa T, Fujiwara T, et al. Differential diagnosis of lung tumor with positron emission tomography: a prospective study. J Nucl Med 1990; 31:1927-1932.
16. Gould GW, Holman GD. The glucose transporter family: structure, function and tissue-specific expression. Biochem J 1993; 295:329-341.
17. Ismail-Beigi F. Metabolic regulation of glucose transport. J Membr Biol 1993; 135: 1-10.
18. James DE. Targeting of the insulin-regulatable glucose transporter (GLUT-4). Biochem Soc Trans 1994; 22:668-670.
19. Goodman MN, Ruderman NB. Starvation in the rat. I. Effect of age and obesity on organ weights, RNA, DNA, and protein. Am J Physiol 1980; 239:E269-E276.
20. Clarys JP, Martin AD, Drinkwater DT. Gross tissue weights in the human body by cadaver dissection. Hum Biol 1984; 56:459-473.
21. Minn H, Leskinen-Kallio S, Lindholm P, et al. [18F]fluorodeoxyglucose uptake in tumors: kinetic vs steady-state methods with reference to plasma insulin. J Comput Assist Tomogr 1993; 17:115-123.
22. Hom FG, Goodner CJ, Berrie MA. A [3H]2-deoxyglucose method for comparing rates of glucose metabolism and insulin responses among rat tissues in vivo: validation of the model and the absence of an insulin effect on brain. Diabetes 1984; 33: 141-152.
23. Ghajar JB, Plum F, Duffy TE. Cerebral oxidative metabolism and blood flow during acute hypoglycemia and recovery in unanesthetized rats. J Neurochem 1982; 38:397-109.
24. Pelligrino DA, Segil LJ, Albrecht RF. Brain glucose utilization and transport and cortical function in chronic vs acute hypoglycemia. Am J Physiol 1990; 259:E729-E735.
25. Keyes J Jr. SUV: standard uptake or silly useless value? J Nucl Med 1995; 36:1836-1839.
26. Hamberg LM, Hunter GJ, Alpert NM, Choi NC, Babich JW, Fischman AJ. The dose uptake ratio as an index of glucose metabolism: useful parameter or oversimplification? J Nucl Med 1994; 35:1308-1312.
27. Curi CM, Ribeiro EB, Zaia CT, Dolnikoff MS. Glycemic response to stress stimulation by ether exposure in adrenalectomized rats. Pharmacol Biochem Behav 1990; 37:399-403.
28. Garber AJ, Cryer PE, Santiago JV, Haymond MW, Pagliara AS, Kipnis DM. The role of adrenergic mechanisms in the substrate and hormonal response to insulin-induced hypoglycemia in man. J Clin Invest 1976: 58:7-15.
29. Torizuka T, Anaira AC, Wahl RL. Effect of hyperglycemia on in vitro rumor uptake of tritiated FDG, thymidine, L-methionine and L-leucine. J Nucl Med (in press).
30. Levin L, Gevers W. Metabolic alterations in cancer. I. Carbohydrate metabolism. S Afr Med J 1981; 59:518-521.
31. Delicado E, Torres M, Miras-Portugal MT. Effects of insulin on glucose transporters and metabolic patterns in Harding-Passey melanoma cells. Cancer Res 1986; 46:3762-3767.
32. Babia T, Denis-Pouxviel C, Murat JC, et al. Insulin controls key steps of carbohydrate metabolism in cultured HT29 colon cancer cells. Biochem J 1989; 261:175-179.