Severe and prolonged jaundice in a lupus nephritis patient treated with cyclophosphamide

Nephrology Dialysis Transplantation

Volumn 12, Issue 4, 1997, Pages 793-796

  Moroni, G ^a   Maccario, M ^a   Fargion, S ^a   Ponticelli, C ^a  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

Cyclophosphamide; Hepatotoxicity; Immunosuppressive therapy; Lupus nephritis

Indexed keywords

CYCLOPHOSPHAMIDE; IMMUNOSUPPRESSIVE AGENT;

ADULT; ARTICLE; CASE REPORT; FEMALE; HUMAN; JAUNDICE; LIVER TOXICITY; LUPUS ERYTHEMATOSUS NEPHRITIS; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ADULT; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASES; BILIRUBIN; CYCLOPHOSPHAMIDE; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; JAUNDICE; LUPUS NEPHRITIS;

EID: 0030894466     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/12.4.793     Document Type: Article

References (15)

1. Ponticelli C, Passerini P. Alkylating agents and purine analogues in primary glomerulonephritis with nephrotic syndrome. Nephrol Dial Transplant 1991; 6: 381-388
2. Donadio JV, Glassock R. Immunosuppressive drug therapy in lupus nephritis. Am J Kidney Dis 1993; 21: 239-250
3. Runyon BA, LaBrecque DR, Anuras S. The spectrum of liver disease in systemic lupus erythematosus. Report of 33 histologically proved cases and review of the literature. Am J Med 1980; 69: 187-194
4. Krawitt EL. Autoimmune hepatitis. N Engl J Med 1996; 334: 897-902
5. Aubrey DA. Massive hepatic necrosis after cyclophosphamide. Br Med J 1970; 3: 588
6. Walters D, Robinson RG, Dick-Smith JB, Corrigan AB, Webb J. Poor response in two cases of juvenile rheumatoid arthritis to treatment with cyclophosphamide. Med J Aust 1972; 2: 1070
7. Bacon AM, Rosenberg SA. Cyclophosphamide hepatotoxicity in patients with systemic lupus erythematosus. Ann Intern Med 1982; 97(1): 62-63
8. Goldberg JW, Lidsky MD. Cyclophosphamide-associated hepatotoxicity. South Med J 1985; 78: 222-223
9. Shaunak S, Munro JM, Weinbren K, Walport MJ, Cox TM. Cyclophosphamide-induced liver necrosis: A possible interaction with azathioprine. Q J Med 1988; 252: 309-317
10. Arai N, Kaneko H, Umeda M, Tsukahara T, Shirai T. Non-Hodgkin's lymphoma in an elderly patient complicated by cyclophosphamide-induced allergic hepatic dysfunction. Nippon-Ronen-Igakkai-Zasshi 1992; 29: 681-685
11. Snyder LS, Heigh RI, Anderson ML. Cyclophosphamide-induced hepatotoxicity in a patient with Wegener's granulomatosis. Mayo Clin Proc 1993; 68: 1203-1204
12. Mildford DV, Butler N, Clarke R, Vaid J. Reversible hepatic dysfunction in association with cyclophosphamide therapy. Eur J Pediatr 1995; 154: 411-412
13. McDonald GB, Hinds MS, Fisher LD et al. Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: a cohort study of 355 patients. Ann Intern Med 1993; 118: 255-267
14. Honjo I, Suou T, Hirayama C. Hepatotoxicity of cyclophosphamide in man: pharmacokinetic analysis. Res Commun Chem Pathol Pharmacol 1988; 61: 149-165
15. Lee WL. Drug-induced hepatotoxicity N Engl J Med 1995; 333: 1118-1127